The Consequences of Multiple Simultaneous C-Type Lectin–Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN

CNS myelin induces regulatory functions of DC-SIGN–expressing, antigen-presenting cells via cognate interaction with MOG

(2014) J.J. García-Vallejo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DCIR interacts with ligands from both endogenous and pathogenic origin

(2013) Karien Bloem et al.   IMMUNOLOGY LETTERS

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion

(2013) Sandra J. van Vliet et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain

(2013) Karien Bloem et al.   PLoS One

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Signaling by Myeloid C-Type Lectin Receptors in Immunity and Homeostasis

(2012) David Sancho et al.   Annual Review of Immunology

Antibodies and carbohydrate ligands binding to DC-SIGN differentially modulate receptor trafficking

(2012) Paul J. Tacken et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation

(2012) Chiara Napoletano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

(2012) Wendy W.J. Unger et al.   JOURNAL OF CONTROLLED RELEASE

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+T cells

(2012) Dapeng Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells

(2012) Juan J. García-Vallejo et al.   MOLECULAR IMMUNOLOGY

Lymph node homing of T cells and dendritic cells via afferent lymphatics

(2012) Reinhold Förster et al.   TRENDS IN IMMUNOLOGY

Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation

(2011) P. J. Tacken et al.   BLOOD

DCIR-mediated enhancement of HIV-1 infection requires the ITIM-associated signal transduction pathway

(2011) A. A. Lambert et al.   BLOOD

Antigen cross-presentation: extending recent laboratory findings to therapeutic intervention

(2011) T. W. H. Flinsenberg et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization

(2011) Satwinder Kaur Singh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

(2010) E. Klechevsky et al.   BLOOD

CD22 Is a Recycling Receptor That Can Shuttle Cargo between the Cell Surface and Endosomal Compartments of B Cells

(2010) M. K. O'Reilly et al.   JOURNAL OF IMMUNOLOGY

Mature dendritic cells use endocytic receptors to capture and present antigens

(2010) C. D. Platt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells

(2008) Abul K. Azad et al.   JOURNAL OF LEUKOCYTE BIOLOGY

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production

(2008) Friederike Meyer-Wentrup et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY