The Known Unknowns of the Human Dendritic Cell Network

Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow

(2015) Jaeyop Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating precursors of human CD1c+and CD141+dendritic cells

(2015) Gaëlle Breton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human blood BDCA-1 dendritic cells differentiate into Langerhans-like cells with thymic stromal lymphopoietin and TGF- 

(2014) C. Martinez-Cingolani et al.   BLOOD

CD1c+ blood dendritic cells have Langerhans cell potential

(2014) P. Milne et al.   BLOOD

pDCs efficiently process synthetic long peptides to induce functional virus- and tumour-specific T-cell responses

(2014) Caroline Aspord et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Dermal CD14 + Cells Are a Transient Population of Monocyte-Derived Macrophages

(2014) Naomi McGovern et al.   IMMUNITY

Human blood dendritic cell subsets exhibit discriminative pattern recognition receptor profiles

(2014) Kristina Lundberg et al.   IMMUNOLOGY

BDCA1-Positive Dendritic Cells (DCs) Represent a Unique Human Myeloid DC Subset That Induces Innate and Adaptive Immune Responses to Staphylococcus aureus Infection

(2014) Jun-O Jin et al.   INFECTION AND IMMUNITY

Human CD141+Dendritic Cells Induce CD4+T Cells To Produce Type 2 Cytokines

(2014) Chun I. Yu et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells Engagement by Influenza Vaccine as a Surrogate Strategy for Driving T-Helper Type 1 Responses in Human Neonatal Settings

(2014) Xiaoming Zhang et al.   JOURNAL OF INFECTIOUS DISEASES

Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines

(2014) Romain Banchereau et al.   Nature Communications

Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments

(2014) Dorothée Duluc et al.   Genome Medicine

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

CD141+ dendritic cells produce prominent amounts of IFN-  after dsRNA recognition and can be targeted via DEC-205 in humanized mice

(2013) S. Meixlsperger et al.   BLOOD

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

(2013) G. Nizzoli et al.   BLOOD

Measles Virus Vaccine-Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells

(2013) J.-B. Guillerme et al.   CLINICAL CANCER RESEARCH

Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation

(2013) Elodie Segura et al.   IMMUNITY

Human CD1c+ Dendritic Cells Drive the Differentiation of CD103+ CD8+ Mucosal Effector T Cells via the Cytokine TGF-β

(2013) Chun I. Yu et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Cross-presentation by human dendritic cell subsets

(2013) Elodie Segura et al.   IMMUNOLOGY LETTERS

Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ–resident dendritic cells

(2013) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+dendritic cells at cross presentation

(2013) Lillian Cohn et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of Human Afferent Lymph Dendritic Cells from Seroma Fluids

(2013) B. Morandi et al.   JOURNAL OF IMMUNOLOGY

Langerhans Cells Favor Skin Flora Tolerance through Limited Presentation of Bacterial Antigens and Induction of Regulatory T Cells

(2013) Angelic M.G. van der Aar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness

(2013) Caroline Hémont et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

Transcriptional Profiling of Human Dendritic Cell Populations and Models - Unique Profiles of In Vitro Dendritic Cells and Implications on Functionality and Applicability

(2013) Kristina Lundberg et al.   PLoS One

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

(2012) G. Schreibelt et al.   BLOOD

Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets

(2012) J. Tel et al.   BLOOD

The differential production of cytokines by human Langerhans cells and dermal CD14+ DCs controls CTL priming

(2012) J. Banchereau et al.   BLOOD

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

(2012) L. F. Poulin et al.   BLOOD

The equivalents of human blood and spleen dendritic cell subtypes can be generated in vitro from human CD34+ stem cells in the presence of fms-like tyrosine kinase 3 ligand and thrombopoietin

(2012) AI Proietto et al.   Cellular & Molecular Immunology

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli

(2012) Andrew J. Kassianos et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Type 2 Myeloid Dendritic Cells Produce Interferon-λ and Amplify Interferon-α in Response to Hepatitis C Virus Infection

(2012) Shuye Zhang et al.   GASTROENTEROLOGY

Human blood dendritic cell antigen 3 (BDCA3)+dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

(2012) Sachiyo Yoshio et al.   HEPATOLOGY

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

(2012) Julien Seneschal et al.   IMMUNITY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

Characterization of resident and migratory dendritic cells in human lymph nodes

(2012) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resident CD141 (BDCA3)+dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

(2012) Chung-Ching Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells

(2012) A. N. Harman et al.   JOURNAL OF IMMUNOLOGY

CD70–CD27 Interaction Augments CD8+ T-Cell Activation by Human Epidermal Langerhans Cells

(2012) Marta E. Polak et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Functional diversity of human vaginal APC subsets in directing T-cell responses

(2012) D Duluc et al.   Mucosal Immunology

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

Differential Capacity of Human Skin Dendritic Cells to Polarize CD4+T Cells into IL-17, IL-21 and IL-22 Producing Cells

(2012) Karine Penel-Sotirakis et al.   PLoS One

Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance

(2011) Oscar Palomares et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency

(2011) Venetia Bigley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Dendritic Cell Subsets from Spleen and Blood Are Similar in Phenotype and Function but Modified by Donor Health Status

(2011) D. Mittag et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Virus Selectively Primes Human Langerhans Cells for CD70 Expression Promoting CD8+ T Cell Responses

(2011) A. M. G. van der Aar et al.   JOURNAL OF IMMUNOLOGY

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

(2010) E. Klechevsky et al.   BLOOD

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Self-renewal capacity of human epidermal Langerhans cells: observations made on a composite tissue allograft

(2010) Jean Kanitakis et al.   EXPERIMENTAL DERMATOLOGY

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+dendritic cells

(2010) Karine Crozat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mouse CD8α+DCs and human BDCA3+DCs are major producers of IFN-λ in response to poly IC

(2010) Henning Lauterbach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Intestinal Lamina Propria CD1c+ Dendritic Cells Display an Activated Phenotype at Steady State and Produce IL-23 in Response to TLR7/8 Stimulation

(2010) S. M. Dillon et al.   JOURNAL OF IMMUNOLOGY

Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation

(2009) Muzlifah Haniffa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Liver Dendritic Cells Promote T Cell Hyporesponsiveness

(2009) Z. M. Bamboat et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells Capture and Cross-Present Viral Antigens from Influenza-Virus Exposed Cells

(2009) Gabrielle Lui et al.   PLoS One

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

(2009) H. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive localization of antigen-presenting cells in human lymph nodes

(2008) C. E. Angel et al.   BLOOD

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B

(2008) Maho Nagasawa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Functional Specializations of Human Epidermal Langerhans Cells and CD14+ Dermal Dendritic Cells

(2008) Eynav Klechevsky et al.   IMMUNITY

Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: differential activation states suggest distinct functions

(2008) Saskia J. A. M. Santegoets et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I

(2008) Tiziana Di Pucchio et al.   NATURE IMMUNOLOGY

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

(2008) Scott H Robbins et al.   GENOME BIOLOGY

Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells

(2007) Jean-Pierre Allam et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY