Review
Nursing
Suzana Aparecida da Costa Ferreira, Carol Viviana Serna Gonzalez, Magali Thum, Adriane Aparecida da Costa Faresin, Kevin Woo, Vera Lucia Conceicao de Gouveia Santos
Summary: A scoping review was conducted to examine the existing literature on topical therapies for malignant fungating wounds pain management. The results showed that most of the studies included non-systematic reviews and case studies, with only a few clinical trials. Further primary studies are needed to inform evidence-based practice.
JOURNAL OF CLINICAL NURSING
(2023)
Editorial Material
Health Care Sciences & Services
Haruka Harano, Ryo Matsunuma, Yukako Tanaka-Yagi, Madoka Ito, Junichi Tasaki, Aki Egawa, Takashi Yamaguchi
Summary: Metronidazole gel or ointment is recommended for treating malodour in malignant fungating wounds, but may not work well in oral lesions due to discomfort and being washed out by saliva. Here we report a case where malodour caused by an oral lesion was effectively controlled with sprayed metronidazole.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2023)
Article
Oncology
Koichi Okajima, Hiroshi Kobayashi, Tomotake Okuma, Sho Arai, Liuzhe Zhang, Toshihide Hirai, Yuki Ishibashi, Masachika Ikegami, Yusuke Shinoda, Toru Akiyama, Takahiro Goto, Sakae Tanaka
Summary: Malignant fungating wounds in soft tissue sarcoma are associated with a poor prognosis, but the incidence of surgical complications and local recurrence after limb-salvage surgery is comparable to general soft tissue sarcoma cases.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Nursing
Miaoning You, Shiyi Zhang, Xiaoxiao Ma, Huimin Liu, Yuhan Lu, Yue Li
Summary: The article summarizes the nursing experience of a patient with non-Hodgkin's lymphoma complicated with a facial malignant wound, including chemotherapy, wound management, and psychological care. Ultimately, the patient's wound symptoms were well controlled and the wound healed completely.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2021)
Article
Dermatology
Agata Janowska, Giulia Davini, Valentina Dini, Michela Iannone, Riccardo Morganti, Marco Romanelli
Summary: The study aimed to optimize the local management and dressing of malignant fungating wounds (MFWs) through a standardized 4-step approach called the PEBO method, resulting in improved Quality of Life (QoL) for most patients but some experienced deterioration in their clinical conditions.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2021)
Review
Biochemistry & Molecular Biology
Beatriz G. Bernardes, Pasquale Del Gaudio, Paulo Alves, Raquel Costa, Carlos A. Garcia-Gonzalez, Ana Leite Oliveira
Summary: Wounds should be managed based on the healing phase and condition, with excessive exudate production posing challenges. Aerogels, especially bio-based ones, offer potential in promoting wound healing and regeneration through their unique properties and nanostructure.
Article
Health Care Sciences & Services
Jeanna M. Qiu, Mary-Jo DelVecchio Good
Summary: This qualitative study explored the experiences and roles of clinicians treating patients with malignant fungating wounds from a multidisciplinary perspective. Three themes emerged: optimizing fragmented care, collaboration between oncology and wound care, and transitioning from curative to palliative care. The study highlights the importance of recognizing when collaboration between specialties is essential for providing the best care for patients.
PALLIATIVE MEDICINE
(2021)
Article
Chemistry, Physical
Wei Zhang, Xue Guan, Xiao Qiu, Tonghuan Gao, Wanying Yu, Mengyuan Zhang, Liru Song, Dan Liu, Jidong Dong, Zaixing Jiang, Dawei Zhang
Summary: In this study, skin-inspired multilayer Janus composite nanofibrous membranes were designed and prepared as wound dressings with superhydrophilicity and superhydrophobicity. The membranes were investigated for their wettability, morphology, in-vitro release, cytotoxicity, antimicrobial activity, and healing effect. Results from animal experiments and histological analysis demonstrated that the composite membranes were more effective in improving the healing of full-thickness defect wounds and promoting the growth of collagen fibers and collagen deposition. The composite membranes consisted of a drug-loading layer with a superhydrophilic surface for self-pumping and drugs backflow, a hydrophobic polyvinylidene fluoride layer for delaying exudates loss, and a superhydrophobic coating with self-cleaning properties for avoiding the adhesion of foreign microorganisms.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Zhenyou Ge, Wenshang Guo, Ye Tao, Haoxiu Sun, Xiangyu Meng, Liangyu Cao, Shanguo Zhang, Weiyu Liu, Muhammad Luqman Akhtar, Yu Li, Yukun Ren
Summary: This article introduces a wearable intelligent wound dressing (IWD) that integrates functions such as wound exudate management, sensor monitoring, closed-loop therapy, and flexible circuit modules to achieve synergy in wound treatment. The dressing can monitor the state of the wound and release drugs as needed, accelerating wound healing.
ADVANCED MATERIALS
(2023)
Review
Nursing
Charles P. Tilley, Mei R. Fu, Jeanna M. Qiu, Christopher Comfort, Brooke L. Crocilla, Zujun Li, Deborah Axelrod
Summary: This systematic review evaluated the relationship between microbiome and symptoms of MFWs, finding that symptom occurrence increased with the number of bacteria species and the presence of anaerobes. Cancer wound-derived odor was associated with specific chemical compounds.
JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING
(2021)
Review
Dermatology
Kevin Woo, Caroline Dowsett, Ben Costa, Stephen Ebohon, Emma J. Woodmansey, Matthew Malone
Summary: The study summarizes the clinical effectiveness of cadexomer iodine in the treatment of chronic wounds, promoting wound bed preparation and healing process by removing barriers to healing.
INTERNATIONAL WOUND JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Zhan Xu, Jialiang Fan, Weiguo Tian, Xin Ji, Yuqian Cui, Qinying Nan, Feifei Sun, Jun Zhang
Summary: This study proposes a multifunctional dressing for the management of diabetic wounds. The dressing has rapid moisture-drained and non-adhesive properties, as well as pH-responsive and antibacterial capabilities. Wound monitoring can be easily conducted using a smartphone integrated with Python-RGB programs. Experimental results show that the dressing has a superior pro-healing rate, collagen deposition, and angiogenesis compared to commercial gauze.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Review
Dermatology
G. Gethin, A. Vellinga, C. McIntosh, D. Sezgin, S. Probst, L. Murphy, P. Carr, J. Ivory, S. Cunningham, A. M. Oommen, Lokesh Joshi, C. Ffrench
Summary: Chronic wounds have a negative impact on individuals' quality of life, and odour is a well-known associated factor. This systematic review examines the effectiveness of topical interventions in managing the odour of chronic and malignant fungating wounds. The review suggests that while metronidazole may provide some improvement, there is a lack of standardized outcomes and robust clinical trials in this area. Further research is needed to evaluate the potential of metronidazole and other interventions in controlling wound odour.
JOURNAL OF TISSUE VIABILITY
(2023)
Article
Health Care Sciences & Services
Hisayuki Ota, Yushi Ueki, Keisuke Yamazaki, Ryusuke Shodo, Takeshi Takahashi, Yusuke Yokoyama, Arata Horii
Summary: This study evaluated the effects of a novel odour transferrer on malodour generated by malignant fungating wounds in head and neck cancer patients. The results showed that the odour score decreased significantly after application of the odour transferrer, indicating its effectiveness in reducing bad odours for patients, their families, and medical staff.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Article
Engineering, Electrical & Electronic
Wei-Cheng Lin, Chun-Ting Hsieh, Ming-Chiu Chang, Chien-Hung Liao
Summary: This article introduces a highly sensitive MEMS cavity-based pH image biosensor with integrated readout circuit in a CMOS bulk technology, featuring a 100 x 100 array. The array displays detailed changes in wound exudate pH image to identify inflammation or spontaneous reepithelization stages, guiding the need to change dressings.
IEEE SENSORS JOURNAL
(2022)
