Article
Medicine, General & Internal
Chul-Hyun Park, Kunwoo Kim, Jin-Tae Hwang, Jae-Hyung Choi, Yong-Taek Lee, Young Sook Park, Jung Ho Park, Kyung Jae Yoon
Summary: This study compared two methods of measuring upper esophageal sphincter (UES) relaxation and determined their diagnostic value in UES relaxation impairment. The results showed that VFSS and HRM have complementary ability in evaluating UES relaxation duration in patients with oropharyngeal dysphagia.
Article
Medicine, Research & Experimental
Joeke L. Nollet, Per Cajander, Lara F. Ferris, Jordache Ramjith, Taher Omari, Johanna Savilampi
Summary: The study aimed to investigate the effects of bolus volume and viscosity on pharyngeal swallow using circumferential pressure sensor technology and found that larger volumes increased intrabolus pressure and all upper esophageal sphincter metrics, while thicker viscosity decreased UES relaxation time and flow timing metrics. The use of this technology provides consistent results with previous reports, offering insights into aberrant pharyngo-esophageal motor responses over time.
Article
Otorhinolaryngology
Sophia M. Colevas, Lily N. Stalter, Corinne A. Jones, Timothy M. Mcculloch
Summary: This study describes the manometric representation of the resting upper esophageal sphincter (UES) using a clinically accessible method of measurement. The results demonstrate excellent within-subject reliability of the resting UES mean pressures and significant effects of age, number of sensors contained within the resting UES, and preceding swallow volume on mean resting UES pressure.
Article
Otorhinolaryngology
Simone Miller, Martin Ptok, Michael Jungheim
Summary: This study investigated the UES reaction to different levels of acidity during swallowing, finding prolonged Restitution Times with stronger acid boluses. Significant differences were found towards neutral and less acidic boluses. Post-Swallow Maximum and Period of Sphincter Activity varied significantly, with higher values for the strongest acid bolus. Relaxation Times showed a slight trend of prolongation with higher bolus acidity, suggesting reflexive protective mechanisms triggered by receptors in the pharyngeal mucosa or UES.
Article
Medicine, Research & Experimental
Dustin Romain, Lauran K. Evans, Yvette Diaz, Kathryn Allen, Kristine Galek
Summary: This study presented a rare case of hypotonic upper esophageal sphincter (UES), with the patient able to achieve a more normal swallow pressure pattern using biofeedback and a specific maneuver during manometry. It also highlighted the importance of combining manometry with other swallow imaging techniques for effective treatment planning and patient outcomes.
Review
Otorhinolaryngology
Sebastian H. Doeltgen, Harsharan Kaur, Stephanie K. Daniels, Leila Mohammadi, Joanne Murray
Summary: The upper esophageal sphincter (UES) is crucial for safe swallowing, and there are various behavioral interventions available to improve UES opening. Different types of interventions have shown varying degrees of success in improving UES opening, with limited evidence base for their effectiveness.
Article
Otorhinolaryngology
Keiko Fukino, Masahiro Tsutsumi, Akimoto Nimura, Koh Miwa, Takashi Ono, Keiichi Akita
Summary: This study examined the connection between the palatopharyngeus and inferior constrictor, finding that the former interlaces with the cricopharyngeal part of the latter through dense connective tissues. This connection may play a role in directly affecting the upper esophageal sphincter and aiding in its opening.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Katharina Winiker, Kristin Gozdzikowska, Esther Guiu Hernandez, Seh Ling Kwong, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study investigated the potential for behavioral modulation of resting pressure at the upper esophageal sphincter (UOS) in healthy adults. Participants were able to increase resting pressure after one week of training, but there was no evidence for purposeful pressure decrease. The capacity for purposeful pressure modulation was influenced by intensive biofeedback training, while healthy subjects may be limited by physiological factors.
Article
Otorhinolaryngology
Katharina Winiker, Kristin Gozdzikowska, Esther Guiu Hernandez, Seh Ling Kwong, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study examined the ability of healthy adults to increase the period of pressure drop in the region of the upper oesophageal sphincter (UOS) during swallowing through volitional UOS pressure modulation. The findings suggest that healthy individuals can volitionally prolong UOS opening duration by modulating pressure at the region of the UOS. However, further training did not enhance performance, indicating a potential limitation in the extent to which the period of pressure drop may be prolonged in healthy individuals.
Article
Medicine, Research & Experimental
Jui-Sheng Hung, Shu-Wei Liang, Taher Omari, Ming-Wun Wong, Wei-Yi Lei, Chih-Hsun Yi, Tso-Tsai Liu, Lin Lin, Chien-Lin Chen
Summary: The effects of baclofen on volitional swallowing measures are limited, but it reduces the likelihood of initiation of piecemeal deglutition to large volume challenges.
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
(2023)
Review
Surgery
Pedro Norton, Fernando A. M. Herbella, Francisco Schlottmann, Marco G. Patti
Summary: This study reviewed the evaluation of the upper esophageal sphincter (UES) using high-resolution manometry (HRM) and found that HRM allows for more precise measurements compared to conventional manometry, but the clinical significance of these parameters still needs confirmation. Various diseases can affect UES function, including achalasia, gastroesophageal reflux disease, globus, neurologic diseases, and Zenker's diverticulum.
LANGENBECKS ARCHIVES OF SURGERY
(2021)
Article
Medicine, General & Internal
Luigi Ruggiero, Paola Iovino, Domenico Gargano, Angela Caloro, Luca De Leo, Antonio D'Antonio, Alessandro Caputo, Antonella Santonicola
Summary: This study evaluated the function of the upper esophageal sphincter (UES) in different esophageal diseases using high-resolution manometry (HRM) and found differences in UES metrics. However, further research is needed to confirm these results and explore their potential applications in clinical practice.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Francis O. Edeani, Mark Kern, Kenan Ulualp, Karlo Kovacic, Patrick Sanvanson, Ling Mei, Reza Shaker
Summary: The study aimed to determine the impact of various factors on deglutitive and non-deglutitive UES parameters, finding that parameters vary across different positions, sexes, ages, heights, and weights. These findings provide important information for clinical evaluation.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Gastroenterology & Hepatology
Taher Omari, Charles Cock, Peter Wu, Michal Marcin Szczesniak, Mistyka Schar, Jan Tack, Nathalie Rommel
Summary: This study aimed to establish a methodology for diagnosing oropharyngeal disorders using P-HRM-I. The results showed that UES relaxation pressure was the best indicator for differentiating patients from controls and diagnosing UES disorders. A diagnostic scheme was also devised to identify patients with UES disorder or propulsive disorder. Additionally, the study found that patients with pharyngeal pressurizations and evidence of reduced UES relaxation and/or distensibility had higher aspiration scores.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Medicine, Research & Experimental
Frederik J. Meisoll, Michael Jungheim, Jacob F. Fast, Simone Miller, Martin Ptok
Summary: The study found that when triggering the laryngeal adductor reflex, two distinct pressure phases of the upper esophageal sphincter were identified, labeled as P1 and P2. P1 phase may be a result of vocal fold activity causing changes in UES pressure, while the constriction during P2 phase could strengthen the barrier function of the UES in preparation to clear the airways.