Article
Multidisciplinary Sciences
Shih-Hao Mao, Bor-Shiuan Shyr, Shih-Chin Chen, Shin-E Wang, Yi-Ming Shyr, Bor-Uei Shyr
Summary: The study found that robotic pancreaticouodenectomy (RPD) had a lower incidence of delayed gastric emptying (DGE) compared to open pancreaticouodenectomy (OPD). Nausea/vomiting, jaundice, malignancy, and lymph node involvement were identified as significant risk factors for DGE. Intraoperative blood loss and postoperative complications were not significantly associated with DGE, but the hospital stay was longer in patients with DGE.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Guido Camps, Elise J. M. van Eijnatten, Glenn A. A. van Lieshout, Tim T. Lambers, Paul A. M. Smeets
Summary: This MRI study found that breast milk emptied faster than infant formula in women with similar initial gastric volume, and that infant formula showed a significantly larger top layer volume in the first 20 minutes after ingestion. MRI in adults may be useful in studying the gastric behavior of infant formula.
JOURNAL OF NUTRITION
(2021)
Article
Multidisciplinary Sciences
Rika Ebara, Shunichi Ishida, Taimei Miyagawa, Yohsuke Imai
Summary: The amplitude and frequency of peristaltic contractions have a significant impact on gastric mixing and emptying. Increasing or decreasing the amplitude affects mixing strength and emptying rate, with higher amplitude increasing the emptying rate and lower amplitude decreasing it. The emptying rate also increases with the peristaltic frequency. The closest contraction wave to the pylorus and subsequent waves promote gastric emptying. It is important to maintain these parameters within normal ranges for healthy gastric function.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2023)
Article
Anesthesiology
Lionel Bouvet, Thomas Schulz, Federica Piana, Francois-Pierrick Desgranges, Dominique Chassard
Summary: This study found that gastric emptying in parturients is delayed after a light meal, and labor epidural analgesia does not worsen but facilitates gastric emptying.
Article
Biotechnology & Applied Microbiology
Haiqiao Zhang, Fengyan Xu, Zhi Zheng, Xiaoye Liu, Jie Yin, Zhenmin Fan, Jun Zhang
Summary: This study evaluated the gastric emptying performance of stomach-partitioning gastrojejunostomy (SPGJ) versus conventional gastrojejunostomy (CGJ) for treating gastric outlet obstruction (GOO). Clinical data showed that SPGJ had better gastric emptying performance and better postoperative clinical efficacy compared to CGJ. Numerical simulation also revealed that the SPGJ model had a higher discharge speed and lower resistance, making it a potentially better option for treating GOO.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Chenxi Wu, Lance T. Hall, David C. Brandon
Summary: An 82-year-old man underwent outpatient nuclear medicine gastric-emptying scintigraphy for dysphagia and regurgitation. The scintigraphy showed delayed gastric emptying but subsequent CT scan and upper gastrointestinal fluoroscopy revealed normal stomach size and function, with an enormously dilated esophagus indicating achalasia. It is important to pay attention to the location and shape of the visualized stomach and recognize that a significantly dilated esophagus can mimic an elongated stomach during scintigraphy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Biology
Shashank Acharya, Sourav Halder, Wenjun Kou, Peter J. Kahrilas, John E. Pandolfino, Neelesh A. Patankar
Summary: In recent decades, in silico modeling has greatly enhanced our understanding of the physiology and biomechanics of organ systems. However, there has been a lack of high-fidelity models for the upper gastrointestinal tract. In this study, we present a detailed numerical model of the upper gastrointestinal tract that incorporates the fiber architecture of the muscle walls and simulates various digestive processes. The model can be used to investigate acid reflux and explore surgical strategies for obesity.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Review
Medicine, General & Internal
Raj K. Goyal
Summary: Research shows that gastric emptying abnormalities in diabetes can lead to postprandial dyspepsia and impaired plasma glucose regulation. Treatment should address whether the emptying is delayed or rapid.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Surgery
Yun Ho Lee, Young Hoe Hur, Hee Joon Kim, Choong Young Kim, Jin Woong Kim
Summary: This study found a higher incidence of delayed gastric emptying (DGE) in patients undergoing pylorus-preserving pancreaticoduodenectomy (PpPD) compared to pylorus-resecting pancreaticoduodenectomy (PrPD) by a single surgeon. Pylorus preservation and clinically relevant postoperative pancreatic fistula were identified as risk factors for DGE.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Gastroenterology & Hepatology
Koichi Kimura, Ryosuke Minagawa, Takuma Izumi, Akihiko Otake, Takehiko Aoyagi, Daisuke Taniguchi, Hiroko Yano, Yuichiro Kajiwara, Kazuhito Minami, Takashi Nishizaki
Summary: This study aimed to investigate the running pattern of the left gastric vein (LGV) and its association with delayed gastric emptying (DGE) after subtotal stomach-preserving pancreatoduodenectomy (SSPPD). The study found that type 3 LGV was most frequently ligated and LGV ligation was an independent risk factor for DGE.
BMC GASTROENTEROLOGY
(2022)
Article
Medicine, Research & Experimental
Fabian Winter, Philipp Schick, Werner Weitschies
Summary: Delayed gastric emptying has a significant impact on drug absorption. Physiologically based pharmacokinetic models can simulate the effects of different meals on gastric emptying. Parameter predictions for gastric emptying can be made using mathematical equations and regression models. This model can simulate the gastric emptying of mixed solid meals with specific meal characteristics using PBPK software.
MOLECULAR PHARMACEUTICS
(2022)
Article
Gastroenterology & Hepatology
Elise J. M. van Eijnatten, Guido Camps, Mathilde Guerville, Vincenzo Fogliano, Kasper Hettinga, Paul A. M. Smeets
Summary: This study aimed to compare gastric emptying rate and protein coagulation after milk consumption between individuals reporting gastrointestinal symptoms and those without symptoms. The results showed no difference in gastric emptying rate between the two groups. The group reporting gastrointestinal symptoms started experiencing symptoms at 30 minutes and had the highest pain rating at 90 minutes. Image texture analysis showed a higher percentage of coagulum and lower percentage of liquid in the gastrointestinal symptom group.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Engineering, Chemical
Liang Li, Cuomu Baima, Jingyu Jiang, Zhendong Liu, Jingjing Wang, Xiao Dong Chen, Peng Wu
Summary: This study quantified the gastric digestion and emptying of a traditional Tibetan diet in elderly individuals. The results showed that elderly individuals had slower gastric emptying rates and impaired protein digestion compared to young adults. These findings highlight the importance of developing food products suitable for the elderly.
JOURNAL OF FOOD ENGINEERING
(2022)
Review
Surgery
Tim H-H Wang, Anthony Y. Lin, Keno Mentor, Gregory O'Grady, Sanjay Pandanaboyana
Summary: This literature review aimed to identify objective measures of DGE following PD and determine their correlation with the clinical definition of DGE. Four objective modalities were found, with gastric scintigraphy showing the most evidence of correlation. However, there is substantial variability in the literature regarding the indications and interpretation of these tests, highlighting the need for a real-time objective modality that correlates with ISGPS DGE definition after PD.
WORLD JOURNAL OF SURGERY
(2023)
Article
Biochemistry & Molecular Biology
Joanna Nadia, Alexander G. Olenskyj, Natascha Stroebinger, Suzanne M. Hodgkinson, Talia G. Estevez, Parthasarathi Subramanian, Harjinder Singh, R. Paul Singh, Gail M. Bornhorst
Summary: This study investigated the effects of food structure on physical breakdown and gastric emptying of solid starch-based foods during gastric digestion. The results showed that the physical properties of the gastric digesta were influenced by gastric secretions and gastric emptying, depending on the buffering capacity and initial macrostructure of the diets. Additionally, differences were found between the proximal and distal stomach regions, and a relationship between gastric breakdown rate and gastric emptying half-time was observed.
