Article
Spectroscopy
Yujing Nie, Shuhan Wang, Youxiu Lin, Wenqiang Lai, Wen Weng, Dianping Tang
Summary: A novel fluorescent probe was developed for the detection of ClO- ions with high sensitivity and selectivity in aqueous media. This nitrogen-fluorine co-doped nanodot probe showed fast quenching response and low limit of detection, making it promising for the analysis of pollutants.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Hojun Moon, Sujeong Kim, Sang Woo Joo, Minkyu Kim, No-Kuk Park, Jeom-In Baek, Ho-Jung Ryu, Joonwoo Kim, Namgyu Son, Misook Kang
Summary: ZnS particles were synthesized with ethylenediamine (en) and its derivatives as capping agents, and the presence of Zn and S defects due to O, N-doping and loading of carbon dots (CDs) was confirmed. Photoluminescence (PL) spectra and density of states calculations suggested the degree of defects. The order of PL intensities and photocurrent densities were found to be ZnS-none > ZnS-EDTA > ZnS-en > ZnS-trien, with ZnS-trien showing extremely slow recombination of photo-excited charges. ZnS-trien was found to be the most suitable for CO2 reduction catalysis, while ZnS-en was the best for water-splitting. The study also revealed that ZnS-trien encapsulated with N-CDs shell maintained excellent photocatalytic activity without photo-corrosion over multiple recycling experiments.
Article
Materials Science, Multidisciplinary
Albina Mikhraliieva, Michael Nazarkovsky, Ricardo Queiroz Aucelio, Yutao Xing, Volodymyr Zaitsev
Summary: Nitrogen-doped carbon nanodots (CNDs) with a high quantum yield of photoluminescence (up to 95%) were synthesized by thermal treatment of citric acid embedded in silica with immobilized N-[3-(Trimethoxysilyl)propyl]ethylenediamine. The use of nanoreactors allowed for the spatial isolation of molecular precursors, resulting in the preparation of high-quality spherical nanoparticles with a size of 2-5 nm. The obtained CNDs exhibited excitation-independent photoluminescence at 453 nm, indicating their potential as efficient photoluminescent materials. The presence of ordered crystalline structures in the CNDs, as revealed by HRTEM, suggests the catalytic effect of the nanoreactor. XPS analysis confirmed the nitrogen doping in the CNDs, with 4.0 at. % of nitrogen atoms incorporated into the graphene core as pyrrolic and ternary fragments.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Analytical
Xiaotong Huang, Chunli Yang, Yingxin Chen, Zebin Zhu, Lihua Zhou
Summary: The highly sensitive and selective fluorescent detection method for PNP was developed using cuttlefish ink-based carbon quantum dots. The method achieved successful detection of PNP in real water samples with satisfactory recoveries, offering a new sustainable waste-prevention strategy and a feasible alternative to traditional PNP detection methods.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Multidisciplinary
Yuchuan Zheng, Shu Wang, Ruifeng Li, Le Pan, Liangqing Li, Zhaopeng Qi, Changjiang Li
Summary: Water-soluble fluorescent carbon dots (C-dots) were prepared using guanine as the sole carbon and nitrogen source through a hydrothermal process. The as-prepared C-dots were characterized to have strong blue photoluminescence, good stability, and high sensitivity for TNP sensing. Real sample analysis indicated potential applications of the C-dots for environmental TNP detection.
RESEARCH ON CHEMICAL INTERMEDIATES
(2021)
Article
Nanoscience & Nanotechnology
Bin Li, Minghui Guo, Xueqi Chen, Yuanyuan Miao
Summary: N and S co-doped mesoporous carbon microspheres were successfully prepared using poplar powder and L-cysteine as precursors. The as-prepared microspheres exhibit globular carbon with a variety of sizes and relatively high specific surface areas. XPS analysis reveals that the microspheres are rich in nitrogen and sulfur functional groups. Electrochemical testing shows that the co-doped microspheres have higher specific capacitance due to reduced internal resistance and increased specific surface area.
ADVANCED COMPOSITES AND HYBRID MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Pengfei Fan, Can Liu, Congcong Hu, Feifei Li, Xi Lin, Fubing Xiao, Hao Liang, Le Li, Shengyuan Yang
Summary: N,S-CDs with strong orange fluorescence were synthesized through a hydrothermal method, showing excitation-independent photoluminescent behavior and excellent stability. A label-free and sensitive detection method for VB12 in drugs was established based on the inner filter effect between VB12 and N,S-CDs.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Wenqi Liu, Qingjun Chen, Feng Zhang, Dongyan Xu, Xiaojin Li
Summary: A new strategy for fabricating atomically dispersed heteroatom-doped nanoporous carbon materials was reported. The catalysts showed greatly improved oxygen reduction reaction (ORR) activity and excellent performance in high temperature proton exchange membrane fuel cells (HT-PEMFC), demonstrating promising potential as low-Pt catalysts.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Engineering, Chemical
Hongmin Cui, Jianguo Xu, Jinsong Shi, Nanfu Yan, Chao Zhang, Shengyong You
Summary: N,S co-doped carbon spheres with high surface area were successfully synthesized by hydrothermal carbonization and activation. The nitrogen doping improved CO2 uptake and selectivity, while the sulfur doping enhanced interaction strength and improved adsorption heat.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2022)
Article
Engineering, Chemical
Yong Gao, Zhaolei Li, Zhen Fu, Haimin Zhang, Guozhong Wang, Hongjian Zhou
Summary: FeS2@NSC composites as a novel electrode material showed high-efficiency selective electrosorption of Cu2+ ions in various cation coexistence systems, with a high coefficient of selectivity. The selective electrosorption behavior of FeS2@NSC electrode was also confirmed in a mixed ions environment, and the mechanism was dominated by Faradic redox reactions.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Wenjing Lu, Lina Hao, Yawei Wang
Summary: N, S-doped ultramicroporous carbons were successfully prepared using L-cysteine as a nitrogen and sulfur source. The ultramicroporous structure and doping provide a high specific surface area and suitable pore size, facilitating the transport and adsorption of electrolyte ions. NSUC-0.4 exhibits high gravimetric capacitance and capacity retention, indicating its potential for practical applications.
Article
Optics
Manjunatha Ganiga, Neema Pallikkarathodi Mani, Jobin Cyriac
Summary: In this study, luminescent S and N co-doped carbon dots (SNCDs) were synthesized and their photophysical properties were investigated. A comprehensive energy level diagram for SNCDs was proposed, explaining the origin of multiple emissive states. Additionally, a highly selective fluorescence detection strategy for Cr(VI) using SNCDs as a fluorophore was demonstrated.
JOURNAL OF LUMINESCENCE
(2022)
Article
Chemistry, Multidisciplinary
Ghazanfar Nazir, Adeela Rehman, Soo-Jin Park
Summary: The research demonstrates that samples activated with K2C2O4 exhibit excellent performance in terms of specific surface area, micropore volume, nitrogen and sulfur content, particularly showing outstanding CO2 adsorption and separation capabilities, surpassing most biomass-derived carbon materials.
JOURNAL OF CO2 UTILIZATION
(2021)
Article
Engineering, Chemical
Bingbing Fan, He Wang, Yonghong Li, Yanmei Zhou
Summary: Nitrogen and sulfur co-doped hierarchical porous carbon spheres were synthesized through hydrothermal carbonization, with diverse morphology changes observed under different conditions. The NSHCS electrode exhibited high specific capacitance due to its specific surface area, heteroatom doping, and porous structure. Furthermore, the assembled symmetrical super-capacitor showed different energy densities in different electrolytes.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2022)
Article
Energy & Fuels
Yue Cao, Yegeng Sun, Ning Han, Xue Li, Qing Wang, Kuizhao Sun, Weimeng Si, Fagang Wang, Xiaolin Zhao, Awais Bokhari, Muhammad Mubashir, Lai Fatt Chuah, Pau Loke Show
Summary: In this work, an economic and environmental in-situ doping synthesis scheme for extensible synthesis Co, N and S doped multiple porous-structure carbon (Co-NSEC) was reported. The Co-NSEC catalysts exhibit excellent ORR performance akin to Pt/C and better alcohol resistance and durability in alkaline solutions.
Article
Chemistry, Analytical
Jinwen Zhu, Zhenzhen Guo, Jinjiang Cui, Peng Miao
Summary: We have developed a simple electrochemical approach for the detection of miRNA. This method involves the design of a programmable DNA tetrahedron that undergoes target-initiated collapse, leading to the integration of recognition, electrode immobilization, signal recruitment, and amplification. The use of duplex-specific nuclease-assisted amplification further enhances the sensitivity of this biosensor. The highly sensitive detection of miRNA is achieved by measuring the sharp silver stripping peak, which also performs well with challenging biological samples. This method offers simplicity, high sensitivity, and practical application potential in clinical diagnosis.
Article
Chemistry, Analytical
Qiwen Bao, Gang Li, Zhengchun Yang, Peng Pan, Jun Liu, Ruizhao Tian, Qianjin Guo, Jun Wei, Wei Hu, Wenbo Cheng, Ling Lin
Summary: This study examined the performance of carbon black and graphene oxide co-doped electrodes and analyzed their contributions to electrochemical performance. A two-layer electrode system was fabricated on a hydrophilic carbon paper surface for the electrochemical detection of tyrosine. The electrode showed increased active area, simplified fabrication process, improved stability and repeatability. The combination of carbon black and graphene oxide formed a solid structure through van der Waals force, adsorption force, and carbon paper substrate. This co-doped electrode will play a significant role in biomedical and civilian detection fields.
MICROCHEMICAL JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Jinwen Zhu, Nan Ouyang, Rongchuan Zhao, Zhenzhen Guo, Jiao Yang, Minxuan Sun, Peng Miao
Summary: In this study, a novel nanocomposite composed of black phosphorus nanosheets, gold nanorods, carbon nanodots, and doxorubicin was prepared. The nanoagents exhibited high antitumor activity due to their broad light absorption, excellent catalytic ability, and significant photothermal and photodynamic effects. The components of the nanocomposite were able to diagnose and guide tumor treatment, induce cell apoptosis, increase the levels of ROS, and enhance the efficacy of photothermal and photodynamic therapies, leading to satisfactory antitumor results.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Jiarong Guo, Mingyue Li, Shipeng Long, Jin Zhu, Peng Miao, Tianxiang Wei, Tao Gao
Summary: Inspired by the structure of a specific protein, a biomimetic catalytic center is constructed for efficient and sensitive detection of nitric oxide (NO) through electrocatalytic oxidation. The electrochemical microsensor exhibits a low detection limit and wide detection range, and has been successfully used for real-time monitoring of NO release by live cells.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hua Chai, Xifeng Chen, Ruiju Shi, Peng Miao
Summary: In this study, a three-dimensional DNA nanostructure based electrochemical platform was developed for duplicate detection of miRNA amplified by nicking endonuclease. Target miRNA levels can be determined by evaluating the electrochemical response. In addition, the triplexes can be disassociated by simply changing pH conditions, and the iTPDNA biointerface can be regenerated for duplicate analyses.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Peng Miao
Summary: miRNAs in circulating blood are regarded as potential biomarkers for diagnosing various diseases. This study introduces a novel electrochemical sensing strategy that combines DNA walker strands on membrane-coated nanomaterials, target-mediated recycling activation, and electrochemical signal enrichment for the detection of miRNAs. The DNA walking nanomachine demonstrates enhanced signal amplification efficiency and easy magnetic separation, allowing for rapid analysis of miRNAs in human circulating blood samples. With its high sensitivity, simple operation, and excellent specificity, this magnetic multipedal DNA walker holds promise for determining miRNA levels in biomedical applications.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Gang Wang, Tao Cheng, Hongxiu Yuan, Fangbo Zou, Peng Miao, Jin Jiao
Summary: In this study, multiple DNA probes were loaded onto 2D Cu-MOF nanosheets to monitor and locate the interaction between circRNA and miRNA in living cells. The nanosheets acted as powerful fluorescence quenchers and nanocarriers of DNA probes for further assembly. This platform showed high sensitivity and co-localization analysis, making it a promising tool for studying the biological functions of circRNA-miRNAs in cancer pathogenesis and for therapeutic applications.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Plant Sciences
Xiao-bao Wang, Meng-li Wang, Yao-juan Chu, Pei-pei Zhou, Xiang-yu Zhang, Jing Zou, Li-hua Zuo, Ying-ying Shi, Jian Kang, Bing Li, Wen-bo Cheng, Zhi Sun, Xiao-jian Zhang, Shu-zhang Du
Summary: This study integrated pharmacokinetics and pharmacometabolomics to explore the active components and therapeutic mechanisms of Mailuo Shutong Pills (MLST) against thromboangiitis obliterans (TAO). The results showed that MLST significantly alleviated TAO symptoms by improving inflammatory cell infiltration and blood supply, and the bioavailable MLST-compounds exhibited positive or negative correlations with TAO-altered metabolites related to glutamate metabolism, histidine metabolism, arachidonic acid metabolism, etc., revealing the synergistic mechanisms of MLST against TAO.
Article
Electrochemistry
Yulin Zhu, Jinwen Zhu, Yan Gao, Jiayue Shi, Peng Miao
Summary: We developed a novel electrochemical approach for detecting the level of FEN1 based on CRISPR and Cas proteins trans-cleavage. This method exhibits high sensitivity and good specificity, enabling direct monitoring of FEN1 in various biological samples and assisting in screening FEN1 inhibitors for potential use in anti-cancer drug discovery.
Article
Engineering, Biomedical
Xiaoyi Ma, Wuping Zhou, Haiwen Li, Bo Zhang, Peng Miao
Summary: In this study, the protection of hetero-nanostructure of MnO2 and AuNPs from salt-induced aggregation was systematically investigated using DNA as a medium. By analyzing the optical responses of these nanostructures, highly sensitive analysis of miRNA can be achieved. The excellent analytical performances are attributed to the unique features of MnO2@Au nanostructures and signal amplification designs, making them promising for the construction of novel biosensors in clinical applications.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Analytical
Qing Qian, Yuguo Tang, Peng Miao
Summary: In this study, a mass-encoded biosensing approach with duplex-specific nuclease (DSN) mediated signal amplification is developed to address the challenges of low abundance and multiplexing. The proposed method successfully detects multiple targets (such as five miRNAs) with high selectivity and sensitivity. Therefore, it can be utilized as an important and valuable tool for quantifying multiplex miRNAs in disease screening and biomedical investigations.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Renpeng Xia, Hua Chai, Jin Jiao, Peng Miao
Summary: Early screening of biomarkers is important for the therapy and prognosis of cancers. MiRNAs encapsulated in tumor-derived exosomes have emerged as biomarkers for early cancer diagnosis. However, traditional methods have limitations that restrict their wide applications. In this study, a convenient electrochemical approach based on DNA triangular pyramid frustum (TPF) and strand displacement amplification was developed for quantification of exosomal miRNA. The biosensor showed excellent analytical performances and successfully analyzed exosomal miRNAs from cells and clinical serum samples.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Environmental
Ruiju Shi, Siyuan Fu, Yuanyuan Xu, Peng Miao
Summary: In this study, a novel electrochemical biosensor for HIV DNA detection was developed, which utilized target induced recycling amplification to enhance sensitivity. Magnetic nanoparticles were used for facile separation and immobilization of target DNA. The proposed method showed excellent sensing performances and was successfully applied in clinical samples.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Zhenzhen Guo, Jinwen Zhu, Jian Yin, Peng Miao
Summary: A novel fluorescent biosensor based on Zeolitic Imidazolate Framework-8 (ZIF-8) nanocomposites is developed for the detection of H2O2 and glucose. The AgNP-CD-ZIF-8 nanocomposites serve as a highly sensitive platform for the analysis of H2O2. This turn-on biosensor can be used for facile and convenient quantification of H2O2 and further extended to detect glucose in real samples.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Ruizhi Liu, Yuge Wang, Hua Chai, Peng Miao
Summary: An electrochemical sensing approach for ultrasensitive MTase activity assay is proposed based on cascade strand displacement polymerization after specific cleavage reaction in the methylated state. This method offers conveniences, high sensitivity, and reliability, making it useful for related biological studies and clinical applications.
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
