Article
Chemistry, Physical
Olena Khrystonko, Silvie Rimpelova, Terezie Burianova, Vaclav Svorcik, Oleksiy Lyutakov, Roman Elashnikov
Summary: In this study, temperature-, pH-, and electro-responsive materials were developed by loading poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAm-co-AAc) microgels into polycaprolactone (PCL) nanofibers. The nanofibers exhibited thermo- and pH-responsive behavior within the range of 31-34 degrees C. Drug release kinetics could be enhanced by applying a pulsed voltage, and long-term temperature- and pH-responsive release was demonstrated. The nanofibers also showed switchable antibacterial activity and supported cell growth. Overall, these nanofibers have potential applications in wound healing.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Nanoscience & Nanotechnology
V. H. Shafeeq, Subash Cherumannil Karumuthil, K. Juraij, Soney Varghese, Sujith Athiyanathil, Unnikrishnan Gopalakrishna Panicker
Summary: Piezoelectric polymer mats were fabricated using electrospinning technique and their ferro-piezoelectric features were confirmed through electrostatic force microscopy and dynamic-contact EFM. The samples showed piezoelectric responses to various activities, indicating the promising potential of fabricating user-friendly piezoelectric mats for physiological motion-sensing applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Polymer Science
Luiza A. Mercante, Kelcilene B. R. Teodoro, Danilo M. dos Santos, Francisco V. dos Santos, Camilo A. S. Ballesteros, Tian Ju, Gareth R. Williams, Daniel S. Correa
Summary: This review highlights the significant advancements in stimuli-responsive antimicrobial electrospun nanofibers, triggered by light, temperature, pH, humidity, and electric field. The strategies employed to design smart electrospun nanofibers with antimicrobial properties are introduced. Recent examples of nanofibers based on different polymers and antimicrobial agents are explored within each stimulus category. The constraints and future directions of stimuli-responsive nanofibrous materials are discussed.
Article
Polymer Science
Seon Ho Choi, Sang Eun Hong, Emad S. Goda, Kuk Ro Yoon
Summary: In this study, electrospun poly((2-methylsulfinyl)ethyl acrylate-co-acrylic acid) (PMSEA-AA) nanofibers were synthesized as wound dressing materials for the first time. These nanofibers exhibited remarkable mechanical properties, hydrophilicity, cell viability, and antibacterial behaviors. Compared to pure acrylic acid (PAA) fibers, PMSEA-AA nanofibers showed higher tensile strength (9 MPa) and elongation at a break (30%), and achieved superior bacterial inhibition zones for Staphylococcus aureus and Escherichia coli.
Article
Pharmacology & Pharmacy
Kangkang Li, Xinlong Zang, Mingyang Cheng, Xuehong Chen
Summary: Recent progresses in fighting against cancer include better understanding of tumor microenvironment and rapid development in nanoscale drug delivery system. Nanocarriers based on polymeric acrylic derivatives have shown high drug encapsulation rate and satisfactory therapeutic outcome in tumor treatment.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Review
Biotechnology & Applied Microbiology
Kai Chen, Yonghui Li, Youbin Li, Yinfeng Tan, Yingshuo Liu, Weisan Pan, Guoxin Tan
Summary: Stimuli-responsive nanofibers prepared by electrospinning are ideal materials due to their large surface area and quick response to external stimuli. As intelligent drug delivery platforms, these nanofibers can efficiently load drugs and release them on-demand under specific conditions such as light, temperature, magnetic field, ultrasound, pH or ROS, showing great potential in various biomedical applications. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Baljinder Singh, Nutan Shukla, Junkee Kim, Kibeom Kim, Myoung-Hwan Park
Summary: This study focuses on the development of a on-demand drug delivery system using NIR-responsive nanofibers containing GNRs and PNIPAM. The system allows controlled drug release through thermal responses, with potential for combination chemotherapy and good biocompatibility. The versatility of the platform was confirmed in cell studies, demonstrating the advantages of the nanofibers' properties in drug delivery.
Article
Engineering, Chemical
Degu Lere Keshebo, Haile Fentahun Darge, Chien-Chieh Hu, Hsieh-Chih Tsai, Chun-Jen Su, Yi-Ming Sun, Wei-Song Hung, Chih-Feng Wang, Kueir-Rarn Lee, Juin-Yih Lai
Summary: In this study, stimuli responsive poly(N-isopropylacrylamide-co-allylamine) exfoliated MoS2 nanosheets laminar membranes were prepared, which exhibited synergistic effects of thermo-responsiveness, antifouling, and photocatalytic behavior. The water permeance of the membrane could be reversibly regulated by the thermo-responsive gates, and the unique tunability of the membrane enabled the separation of different sized molecules.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Polymer Science
Xiaoyu Guan, Hong Xia, Qing-Qing Ni
Summary: Electrospun nanofibrous yarns based on shape memory polyurethane (SMPU) were successfully prepared, with the 60 degrees twisted yarn showing improved mechanical properties and shape memory recovery stress compared to non-twisted SMPU nanofibers. This yarn also demonstrated a high load-bearing capacity and potential applications in the medical and biological fields as actuators and sensors.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Kandiyil Juraij, V. H. Shafeeq, Akash M. M. Chandran, Suni Vasudevan, Prasanna Kumar S. Mural, Athiyanathil Sujith
Summary: This study develops a novel thermoplastic polyurethane/nanohydroxyapatite electrospun composite membrane-based piezoelectric nanogenerator (PENG) using polydimethylsiloxane as the substrate. The addition of nanohydroxyapatite and oxidized multiwalled carbon nanotube transforms the non-piezoelectric polyurethane into a piezoelectric composite material. Compared to pristine electrospun polyurethane, the composite samples show improved mechanical properties, thermal stability, dielectric properties, and piezoelectric characteristics. The optimized nanofibrous sample modified with the nHA/o-MWCNT hybrid filler exhibits exceptional dielectric properties and piezoelectric characteristics.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Physical
Constantinos Voniatis, Kenigen Manikion, Gergo Gyulai, Angela Jedlovszky-Hajdu
Summary: Tissue integration is a major challenge in tissue engineering and tissue scaffold development. This study explores the use of blend and composite materials to improve tissue integration. Poly(lactic acid) PLA and polysuccinimide (PSI) are used as the polymer components. The results show that the blend-electrospun meshes have a pronounced 3D structure and increased hydrophilicity. However, the blend meshes performed poorly in terms of degradation.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Biochemistry & Molecular Biology
Lais Ramos Monteiro Lima, Everton Lucas de Lima Ramos, Maria Francilene Souza Silva, Fabio de Oliveira Silva Ribeiro, Jeanlex S. Sousa, Claudia Pessoa, Durcilene Alves Silva, Judith P. A. Feitosa, Haroldo C. B. Paula, Regina Celia Monteiro de Paula
Summary: In this study, aminated poly(N-isopropylacrylamide) was successfully grafted onto oxidized galactomannan polysaccharide from Delonix regia via Schiff base reaction. The self-organizing ability of the obtained nanoparticle copolymers was investigated, showing promising potential for drug delivery with good cell viability and transition temperature close to human body temperature. The use of free aldehyde groups in the oxidized polysaccharide for pro-drug formation with substances possessing NH2 groups was also highlighted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biophysics
Kianoush Karimipour, Jaber Keyvan Rad, Sakine Shirvalilou, Samideh Khoei, Ali Reza Mahdavian
Summary: This study presents a method for reversible and remote cell manipulation using photoresponsive nanofibers, and explores its potential application in cell tissue engineering. The experiments demonstrate that the nanofibers exhibit high photoresponsivity and biocompatibility.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Polymer Science
Shu Wang, Purushottam Poudel, Felix H. Schacher, Leonid I. Kaberov
Summary: In this work, a method for synthesizing temperature and light-responsive copolymers by introducing azobenzene fragments in the side chain of poly(2-oxazoline)s is proposed. The obtained copolymers exhibited thermo-responsive behavior and reversible isomerization of azobenzene units under UV and visible light exposure. The presence of nanoparticles in the aqueous solutions of the copolymers was confirmed, and the size of these nanoparticles changed in response to UV irradiation.
Article
Multidisciplinary Sciences
Fatemeh Jamali, Negar Etminani-Esfahani, Abbas Rahmati
Summary: Poly(acrylic acid-co-acrylamide-co-maleic acid) (p(AA-co-AM-co-MA)) superabsorbent polymer was synthesized and its structure, morphology, and strength were characterized. The water absorbency, water retention ability, and reusability of the superabsorbent were investigated, showing high performance in distilled water and saline solution. The response ability of the superabsorbent to temperature, pH, and ionic strength changes was confirmed by swelling and shrinking behavior.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Zaiqian Yu, Dongyan Tang, Haitao Lv, Qian Feng, Qingnan Zhang, Enying Jiang, Qidong Wang
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2015)
Article
Chemistry, Multidisciplinary
Yudi Guo, Dongyan Tang, Erqing Zhao, Zaiqian Yu, Haitao Lv, Xinyu Li
Article
Materials Science, Multidisciplinary
Zaiqian Yu, Haitao Lv, Dongyan Tang
Article
Chemistry, Physical
Qian Feng, Dongyan Tang, Zaiqian Yu, Shuo Gu, Enying Jiang
SURFACE REVIEW AND LETTERS
(2013)
Article
Chemistry, Physical
Jing Peng, Dongyan Tang, Haitao Lv, Ning Wang, Xu Yang, Zhaojie Sun, Zaiqian Yu
COLLOID AND POLYMER SCIENCE
(2019)
Article
Engineering, Chemical
Zaiqian Yu, Jianwei Yi, Dongyan Tang
SEPARATION AND PURIFICATION TECHNOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Wenqiao Du, Zaiqian Yu, Xin Wang, Jingdong Wu, Long Zhang
Summary: A novel hydroxyl radical exfoliation method of commercial graphite into graphene was developed using potassium formate and polyaspartic acid as electrical conductor and exfoliation assistant, achieving a high yield of 98.2% with low defects and 92% content of 2-layer graphene at optimal parameters. This clean and cost-effective strategy shows practical promise for large-scale preparation of higher quality graphene from low-cost commercial graphite.
REACTION CHEMISTRY & ENGINEERING
(2022)
Article
Polymer Science
Xue Li, Zaiqian Yu, Long Zhang
Summary: In this study, green reactive flame-retardant polyether polyols (GPP) were successfully synthesized by the ring-opening polymerization of environmentally friendly melamine resin (EFMR) with propylene oxide, and applied to prepare flame-retardant rigid polyurethane foams (RPUFs). The addition of GPP greatly improved the thermal stability and flame retardancy of the RPUFs, making them commercially viable. The GPP shows great potential for the development of specified flame-retardant PU materials.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Zaiqian Yu, Hongjuan Gu, Dongyan Tang, Haitao Lv, Yonghui Ren, Shuo Gu
Proceedings Paper
Engineering, Environmental
Qingnan Zhang, Dongyan Tang, Zaiqian Yu, Haitao Lv
MATERIALS SCIENCE AND PROCESSING, ENVIRONMENTAL ENGINEERING AND INFORMATION TECHNOLOGIES
(2014)
Proceedings Paper
Engineering, Manufacturing
Chunqing Huo, Hongjuan Gu, Zaiqian Yu, Long Zhang
PROGRESS IN MATERIALS AND PROCESSES, PTS 1-3
(2013)
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
