In vitro and in vivo therapeutic siRNA delivery induced by a tryptophan-rich endosomolytic peptide

Modification of a Designed Amphipathic Cell-Penetrating Peptide and Its Effect on Solubility, Secondary Structure, and Uptake Efficiency

(2013) Mousa Jafari et al.   BIOCHEMISTRY

A New Amphipathic, Amino-Acid-Pairing (AAP) Peptide as siRNA Delivery Carrier: Physicochemical Characterization and in Vitro Uptake

(2012) Mousa Jafari et al.   JOURNAL OF PHYSICAL CHEMISTRY B

RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo

(2011) O Hibbitt et al.   GENE THERAPY

Special delivery: targeted therapy with small RNAs

(2011) D Peer et al.   GENE THERAPY

Anti-tumor efficacy of naked siRNAs for ERBB3 or AKT2 against lung adenocarcinoma cell xenografts

(2011) Gunamani Sithanandam et al.   INTERNATIONAL JOURNAL OF CANCER

RNAi-based therapeutic strategies for metabolic disease

(2011) Michael P. Czech et al.   Nature Reviews Endocrinology

RNAi-Based Treatment for Neovascular Age-Related Macular Degeneration by Sirna-027

(2010) Peter K. Kaiser et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents

(2010) Nikken Wiradharma et al.   BIOMATERIALS

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Designer Lipids Advance Systemic siRNA Delivery

(2010) Yang Liu et al.   MOLECULAR THERAPY

Poly(oligo-D-arginine) With Internal Disulfide Linkages as a Cytoplasm-sensitive Carrier for siRNA Delivery

(2010) Young-Wook Won et al.   MOLECULAR THERAPY

Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells

(2010) M. S. Goldberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy

(2009) Yuki Takahashi et al.   ADVANCED DRUG DELIVERY REVIEWS

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

Systemic Delivery and Quantification of Unformulated Interfering RNAs In Vivo

(2009) Aurelie Morin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

RNA interference-based gene therapy for successful treatment of rheumatoid arthritis

(2009) Gabriel Courties et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Polyplexes from Poly(aspartamide) Bearing 1,2-Diaminoethane Side Chains Induce pH-Selective, Endosomal Membrane Destabilization with Amplified Transfection and Negligible Cytotoxicity

(2008) Kanjiro Miyata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY