Article
Polymer Science
Konstantin A. Milakin, Zuzana Moravkova, Udit Acharya, Martina Kasparova, Stefan Breitenbach, Oumayma Taboubi, Jiri Hodan, Jirina Hromadkova, Christoph Unterweger, Petr Humpolicek, Patrycja Bober
Summary: Polyaniline-based cryogels prepared by oxidative cryopolymerization with poly(N-vinylpyrrolidone) and phytic acid showed improved mechanical strength and stability, but changes in conductivity and specific surface area were observed. Optimal concentration of phytic acid enhanced material conductivity and surface area, while improving tensile modulus and cytocompatibility of the cryogels.
Article
Nanoscience & Nanotechnology
Ksenia Loskutova, Mar Torras, Ying Zhao, Anna J. Svagan, Dmitry Grishenkov
Summary: The aim of this study was to investigate the effect of cellulose nanofiber (CNF)-shelled perfluoropentane (PFP) droplets on the cell viability of 4T1 breast cancer cells, with or without the addition of non-encapsulated paclitaxel. CNF-shelled PFP droplets were produced and their size distribution and concentration were analyzed. The thermal stability and blood compatibility of CNF-shelled PFP droplets were also evaluated. The results showed that CNF-shelled PFP droplets have the potential to be used as drug carriers in ultrasound-mediated therapy as they did not affect cell viability and displayed no hemolysis.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Chun-Nan Wu, Te-En Wang, Chen-Che Hsieh, Kuan-Chen Cheng, Kevin C. W. Wu
Summary: Developing biocompatible and antibacterial PLLA/TOCNF/AgNP films is a promising strategy to address public health issues and plastic pollution.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Jiao Liu, Huiyuan Zhai, Yaning Sun, Shaohua Wu, Shaojuan Chen
Summary: Development of ultra-strong and biocompatible nanofiber yarns for biomedical textile materials presents significant challenges. PLLA nanofiber yarns exhibit exciting mechanical properties and enhanced biocompatibility compared to commercial PLLA microfiber yarns, showing potential for future commercial applications in bio-textiles.
Article
Materials Science, Multidisciplinary
Victor K. Sharma, Gourhari Chakraborty, Soundararajan Narendren, Vimal Katiyar
Summary: In this study, biodegradable polyvinyl alcohol (PVA) was covalently grafted onto surface-modified carbon nanofibers (mCFs) to form a highly conductive nanocomposite. This nanocomposite was then used to create flexible and conductive nanofiber mats through electrospinning or dip-coating methods. The resulting nanofiber mats exhibited excellent structural flexibility, high electrical conductivity, and thermal stability, making them suitable for applications in biofuel cell electrodes, biomedical devices, and wearable electronics.
MATERIALS ADVANCES
(2023)
Article
Materials Science, Textiles
Jiahan Yang, Tongda Lei, Xue Yang, Jie Fan, Huancheng Wu, Sen He, Wei Liu, Yong Liu
Summary: In this study, three ecofriendly low-cost methods, hot air, pure oxygen, and ultraviolet irradiation, were used as post-crosslinking treatments to prepare a keratin/PEO nanofiber membrane with good water tolerance. The three methods effectively transformed the water-soluble membrane into a water-insoluble membrane, and supported cell adhesion and proliferation. This provides potential for tissue engineering and biomedical applications.
FIBERS AND POLYMERS
(2023)
Article
Nanoscience & Nanotechnology
Sujin Cha, Eugene Lee, Gilsoo Cho
Summary: In this work, transparent conducting electrodes (TCEs) based on PEDOT:PSS/PVDF nanofiber web were fabricated for dye-sensitized photovoltaic textiles. The TCEs showed high transparency and conductivity, making them suitable for applications in dye-sensitized photovoltaic textiles.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Textiles
Ting Zhu, Lei Zhao, Manyu Qian, Danni Yu, Jihuan He, Weiqing Jiang, Jun Wang, Shuqiang Wang
Summary: The electrospinning technology developed by bionic spider spinning improves the molecular structure and mechanical properties of nanofibers and produces nanofibers and base membrane products with enhanced mechanical properties. By harnessing a long spiral-needle, minimal energy is consumed in the spider spinning process. The addition of dopamine results in denser pore size distribution, increased fracture strength, and elongation at break. A nanofiber membrane is obtained through oxidative polymerization of dopamine.
JOURNAL OF ENGINEERED FIBERS AND FABRICS
(2023)
Article
Engineering, Environmental
Wei Lyu, Jiaqiang Li, Miroslava Trchova, Guang Wang, Yaozu Liao, Patrycja Bober, Jaroslav Stejskal
Summary: In this study, three-dimensional polyaniline/poly(vinyl alcohol)/montmorillonite (PANI/PVAL/MMT) hybrid aerogels with easy separation performance and highly effective reusable adsorption on both anionic and cationic dyes were successfully fabricated by a simple in-situ polymerization method. The resulting hybrid aerogels showed a well-defined hierarchical structure with PANI nanofibers coated on the skeleton wall. The adsorption performance of the hybrid aerogels on anionic and cationic dyes was systematically studied, demonstrating their excellent adsorption capacity.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Biomedical
Jiao Chen, Xuanze Li, Qin Liu, Ying Wu, Liping Shu, Zhixu He, Chuan Ye, Minxian Ma
Summary: In this study, multilayer nanofiber scaffolds with different polymer concentrations were fabricated using multilayer electrospinning technique and their properties were examined. It was found that scaffolds with a PVP-to-PEO mass ratio of 0.96 g: 0.24 g showed excellent biocompatibility and mechanical properties, demonstrating promising application potential in tissue engineering.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Biochemistry & Molecular Biology
Tiantang Fan, Jingwen Qin, Jiafeng Li, Jifa Liu, Ying Wang, Qing Liu, Tianyun Fan, Fengzhen Liu
Summary: The study introduces flexible p-dioxanone (PDO) and highly reactive glycolide (GA) units into poly(L-lactic acid) (PLLA) to prepare poly(L-lactide-ran-p-dioxanone-ran-glycolide) (PLPG) copolymers. The copolymers are then processed into PLPG scaffolds using 3D printing technology. The results show that introducing PDO and GA units improves the mechanical and degradation properties of the PLLA scaffolds, and the PLPG scaffolds support cell proliferation, growth, and differentiation. The controllable degradation rates and mechanical performance of the PLPG scaffolds make them potentially useful in bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Vieralynda Vitus, Fatimah Ibrahim, Shamsul Azlin Ahmad Shamsuddin, Nuguelis Razali, Noor Anastasha Balqis Noor Azlan, Wan Safwani Wan Kamarul Zaman
Summary: The usage of carbon derived from biomass waste is increasing in various fields due to its availability, cost-effectiveness, and sustainability, but its application in tissue engineering is still limited. In this study, carbon derived from human hair waste was used to fabricate a carbon-based bioscaffold, which showed potential for tissue engineering applications based on its properties and compatibility with stem cells.
Article
Multidisciplinary Sciences
W. Ishwarchand Singh, Sayantan Sinha, Naorem Aruna Devi, Sumitra Nongthombam, Soumyadeep Laha, Bibhu P. Swain
Summary: Reduced graphene oxide and polyaniline nanocomposites were synthesized and fabricated into nanofibers using electrospinning, with the addition of polycaprolactone. The incorporation of polyaniline was found to decrease the optical band gap, and the resulting nanofibers exhibited favorable morphology and chemical properties.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2022)
Article
Engineering, Biomedical
Yevhen Samokhin, Yuliia Varava, Kateryna Diedkova, Ilya Yanko, Yevheniia Husak, Julia Radwan-Praglowska, Oksana Pogorielova, Lukasz Janus, Maksym Pogorielov, Viktoriia Korniienko
Summary: The study presents a strategy for producing porous composite fibrous materials with excellent biocompatibility and antibacterial performance. The addition of PEG into the spinning solutions has a significant impact on the fiber characteristics, including diameter, morphology, and porosity. The hybrid fibrous materials, consisting of modified chitosan (Ch), polylactic acid (PLA), and PEG, show promising potential for biomedical applications due to their slower degradation rate, reduced hydrophobicity, and enhanced antibacterial activity.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Engineering, Environmental
Wei Lyu, Jiaqiang Li, Linlin Zheng, He Liu, Jian Chen, Weiyi Zhang, Yaozu Liao
Summary: PCNFA was developed as a nanostructured adsorbent for organic dye pollutants removal, exhibiting high compressive stress and adsorption capacity. The PDS process was used for the regeneration of PCNFA, maintaining high adsorption capacity for dyes even after multiple cycles. The electrostatic and 7C-7C stacking interactions were identified as driving forces for adsorption, with nonradical reactions contributing to the regeneration of PCNFA.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Multidisciplinary Sciences
Wei Tang, Zhen Yang, Liangcan He, Liming Deng, Parinaz Fathi, Shoujun Zhu, Ling Li, Bo Shen, Zhantong Wang, Orit Jacobson, Jibin Song, Jianhua Zou, Ping Hu, Min Wang, Jing Mu, Yaya Cheng, Yuanyuan Ma, Longguang Tang, Wenpei Fan, Xiaoyuan Chen
Summary: The study introduces a novel nanomaterial assembly that significantly alleviates tumor hypoxia and enhances radiotherapy efficacy by increasing intratumoral oxygen supply while reducing oxygen consumption, demonstrating a potential strategy to address a major limitation in radiotherapy.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Boyang Wang, Jingkun Yu, Laizhi Sui, Shoujun Zhu, Zhiyong Tang, Bai Yang, Siyu Lu
Summary: This study reports a new type of full-color emission carbon dots material, and a simple, convenient hydrothermal preparation method guided by theoretical calculations has been developed, showing great potential for various applications.
Review
Biotechnology & Applied Microbiology
Mengqi Guan, Shoujun Zhu, Shanshan Li
Summary: Melanoma is an aggressive type of skin cancer with increasing incidence and high mortality rates worldwide. Nanomedicine, an emerging area in the medical field, is being widely investigated in small animal models to afford melanoma theranostics. However, unresolved issues such as tumor heterogeneity and drug resistance with single therapy still exist.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Camilla Kofoed Andersen, Sangita Khatri, Jonas Hansen, Sofie Slott, Rohith Pavan Parvathaneni, Ana C. Mendes, Ioannis S. Chronakis, Shu-Chen Hung, Narendiran Rajasekaran, Zhuoran Ma, Shoujun Zhu, Hongjie Dai, Elizabeth D. Mellins, Kira Astakhova
Summary: PEGylated single-walled carbon nanotubes show high efficiency in serving as carriers for methotrexate and siRNA, enabling targeted delivery to immune cells. By altering the ratio of MTX and siRNA, the specificity of targeting to immune cells can be adjusted accordingly.
Article
Optics
Qingsen Zeng, Tanglue Feng, Songyuan Tao, Shoujun Zhu, Bai Yang
Summary: Carbon dots (CDs) have garnered significant attention in the past decade for being easy-to-prepare, non-toxic, and customizable fluorescent nanomaterials. They can be categorized into three subgroups based on their morphology and chemical structure, with detailed structures varying significantly, especially in chemically synthesized CPDs. Proper nomenclature is crucial for the better utilization of the diverse structures and properties of CPDs.
LIGHT-SCIENCE & APPLICATIONS
(2021)
Article
Materials Science, Biomaterials
Xiaomeng Wang, Xiaoduo Tang, Nuo Li, Yihan Sun, Ruotong Yu, Junhu Zhang, Daowei Li, Bai Yang, Hongchen Sun
Summary: This study proposes a new strategy for effective infectious burn wound healing by inducing partial epithelial-to-mesenchymal transition (EMT). The adhesive hydrogel patch, composed of black phosphorus nanosheets, catechol-modified chitosan, and oxidized dextran, can orchestrate key early skin wound healing processes and restore the intact epithelial barrier through fast induction of partial EMT.
BIOMATERIALS SCIENCE
(2022)
Article
Engineering, Biomedical
Nianzuo Yu, Feiran Zhang, Xiaoduo Tang, Yongshun Liu, Junhu Zhang, Bai Yang, Quan Wang
Summary: A microfluidic spotting-screening platform (MSSP) has been developed for controlling the effect of extracellular matrix on cell development. The MSSP can precisely control the behavior of mesenchymal stem cells, such as adhesion and differentiation, and provides a feasible and high-throughput platform for hydrogel-microarray-based materials.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Multidisciplinary
Yajun Wang, Jingjie Nan, Huilong Ma, Jiajun Xu, Feifei Guo, Yufeng Wang, Yongye Liang, Junhu Zhang, Shoujun Zhu
Summary: A modular theranostic system combining NIR-II FGS and a sandwiched plasmonic chip (SPC) was developed for intraoperative detection and resection of tumor cells in lymph nodes with high sensitivity and selectivity. The system achieved accurate diagnosis and improved efficiency of cancer therapy.
Article
Multidisciplinary Sciences
Xiaoduo Tang, Jingyan Ren, Xin Wei, Tao Wang, Haiqiu Li, Yihan Sun, Yang Liu, Mingli Chi, Shoujun Zhu, Laijin Lu, Junhu Zhang, Bai Yang
Summary: The authors have developed a hydrogel patch that releases carbon monoxide and nitric oxide gases on demand, which can provide timely blood supply for skin flap transplantation during surgery, reducing the incidence of flap necrosis and long-term functional loss.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Xingchen Cui, Zhezhi Liu, Bing Zhang, Xiaoduo Tang, Fuqiang Fan, Yu Fu, Junhu Zhang, Tieqiang Wang, Fanbao Meng
Summary: Actuators based on hydrogels are promising for biomimetic soft robots. However, their actuation process lacks perceptual capacity. This study proposes a fast photo-thermal responsive and self-sensory soft actuator based on a sponge-like hydrogel, demonstrating ultrafast response and self-sensing capabilities. Inspired by neuromuscular systems, a smart self-adaptive actuator is designed, enabling active perception and shape transformation. This sensory actuating hydrogel contributes to the development of artificial intelligent soft robotics with higher autonomy and complexity.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Feiran Zhang, Jiajun Xu, Chengbin Zhang, Yin Li, Jiawei Gao, Limei Qu, Songling Zhang, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: Accurate identification of tumor margins during cancer surgeries is essential, and a high-throughput detection technique is needed. The conventional histopathological analysis of frozen tissue sections often shows variability, especially in areas without trained pathologists. This study introduces a high-throughput three-dimensional histological electrophoresis device that utilizes tumor-specific proteins to identify and contour tumor margins intraoperatively. Testing on xenograft models and human cervical cancer models demonstrated the effectiveness of this approach. The device is expected to improve the accuracy and efficiency of diagnosing various cancers.
Article
Multidisciplinary Sciences
Feiran Zhang, Jiajun Xu, Ying Yue, Yajun Wang, Jianing Sun, Dong Song, Chengbin Zhang, Limei Qu, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: This study introduces a three-dimensional histological electrophoresis system, which can rapidly label and separate proteins within tissue sections during surgical excision of tumors, providing a more precise and automated pathological diagnosis for assessing tumor-positive margins.
Article
Chemistry, Multidisciplinary
Jingjie Nan, Yuan Chen, Weihong Sun, Ying Yue, Yuanyuan Che, Hongli Shan, Wei Xu, Bin Liu, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: This study developed a novel label-free and naked-eye readable microarray technique for quick antibody analysis. The technique is fast, accurate, and flexible, allowing for large-scale SARS-CoV-2 antibody detection and analysis of antibodies against multiple virus variants.
Article
Nanoscience & Nanotechnology
Yihan Sun, Manxuan Liu, Xiaoduo Tang, Yanmin Zhou, Junhu Zhang, Bai Yang
Summary: Probiotic therapy in infected wound healing is hindered by low viability and colonization efficiency. In this study, a culture-delivery live probiotics hydrogel dressing was developed to maintain the activity of probiotics and limit leakage, resulting in sustainable antimicrobial effects.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Hang Yu, Zhina Wu, Xingfu Bao, Xiaoduo Tang, Junhu Zhang, Yi Zhang, Min Hu
Summary: Orthodontic tooth movement (OTM) may cause orthodontically induced inflammatory root resorption (OIIRR), which affects tooth health and treatment stability. In this study, a composite hydrogel named CCOD-Trametinib (CCOD-Tra) was developed to prevent OIIRR. The CCOD-Tra hydrogel exhibited good biocompatibility, injectability, and sustained release of Trametinib (Tra). Animal and cell experiments demonstrated that CCOD-Tra effectively prevented OIIRR by inhibiting osteoclast differentiation and maturation through the ERK1/2 signaling pathway.
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
