Article
Pharmacology & Pharmacy
Mengru Chen, Yunyun Chen, Yanbao Zhao, Xueyan Zou, Lei Sun
Summary: In this study, three types of mesoporous silica nanoparticles with different aspect ratios were prepared. The samples showed that aspect ratio affects specific surface area, cell uptake rate, and drug loading capacity. The MS3 sample, with higher cell uptake rate and specific surface area, was used as a carrier for drug delivery system, displaying redox/pH-responsive and sustained release behavior.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Environmental
Wen Ma, Xinglin Lu, Yan-Fang Guan, Menachem Elimelech
Summary: This study introduces the use of a Joule-heated sponge for rapid silica removal in saline waters, effectively mitigating silica scaling in membrane desalination processes. Joule-heating enhances silica removal kinetics and sponge regeneration efficiency, demonstrating great potential for controlling silica scaling in various engineered processes.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Maarten Everaert, Erik Smolders, Mike J. McLaughlin, Ivan Andelkovic, Simon Smolders, Fien Degryse
Summary: Molybdenum is an essential plant micronutrient, with deficiencies often seen despite low plant requirements. ZnAl layered double hydroxides (LDHs) loaded with molybdate were studied as potential slow-release Mo compounds, showing varying desorption effects in different soil environments.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Alysson F. Morais, Dimy Nanclares, Ivan G. N. Silva, Alfredo Duarte, Fernando A. Garcia, Eric Breynaert, Danilo Mustafa
Summary: Synthesis of layered materials with hierarchical porosity remains challenging, but using a soft-templating strategy and introducing Eu3+ has been shown to result in the self-assembly of layered nanotubes with multilayer cylinders, greatly increasing the specific surface area of the materials.
Article
Chemistry, Multidisciplinary
Apuchu R. Sangtam, Pinky Saikia, Rajib L. Goswamee, Upasana B. Sinha
Summary: The study investigates the thermokinetic behavior of mesoporous Ni-Co layered double hydroxide (LDH) through non-isothermal kinetic heating programs and analyzes various kinetic parameters such as activation energies and reaction models. The results show that the degradation of Ni-Co LDH follows a kinetically complex process, influenced by factors like physisorbed gas or moisture. The analysis of pseudo-components reveals that the degradation process is controlled by individual peak components at different temperature ranges.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Pharmacology & Pharmacy
Nicolas Jackson, Andrea C. C. Ortiz, Alejandro Jerez, Javier Morales, Francisco Arriagada
Summary: Stimuli-responsive nanomaterials have been studied as a promising strategy for anticancer therapy, with pH-responsive silica nanocarriers being particularly effective in controlled drug delivery in acidic tumor microenvironments. The design of the nanocarrier and drug release mechanisms play a crucial role in optimizing efficacy, and this study provides new insights into the behavior of a hydrophobic drug released from a pH-sensitive nanosystem.
Article
Biochemistry & Molecular Biology
Zhongtao Li, Jing Guo, Guiqiang Qi, Meng Zhang, Liguo Hao
Summary: A pH-responsive and imaging nanocarriers system using mesoporous silica nanoparticles (MSNs) doped with gadolinium (Gd) was developed. The system showed pH-responsiveness and high biocompatibility, and the T1 contrast was significantly enhanced by Gd, making it a promising system for cancer diagnosis and treatment.
Article
Chemistry, Physical
Wenjun Liu, Kun Jiang, Yiming Hu, Qian Li, Yilin Deng, Jian Bao, Yucheng Lei
Summary: The Zr-doped layered double hydroxide on nickel foam was designed to enhance the bifunctional activities of electrocatalysts, showing superior OER and HER activities in 1M KOH and alkaline simulated seawater electrolyte. The CoFeZr/NF provides a new pathway for large-scale hydrogen production, with almost no attenuation when tested in alkaline seawater electrolyte compared to 1.0 M KOH.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Hua Pan, Weilan Huang, Litao Wu, Qihao Hong, Zhongxuan Hu, Meijing Wang, Fang Zhang
Summary: Integrating pesticides and mineral elements into a multi-functional nanocarrier can synergistically protect plants and provide nutrients. The pH dual-responsive nanosystem developed in this study effectively delivered a fungicide to target organisms and promoted plant growth, while showing no obvious toxicological influence on bacteria and cell viability.
Article
Crystallography
Changxin Wei, Xiaoyun Yan, Yi Zhou, Wenke Xu, Yiqi Gan, Yihe Zhang, Na Zhang
Summary: Layered double hydroxides (LDHs) play an important role in various applications due to their biocompatibility, chemical versatility, and high theoretical capacity. This study investigates the crystal morphology control and exfoliation of LDHs. It is found that the interlayer spacing of LDH decreases with the affinity of intercalating ions, making it more difficult to exfoliate into nanosheets. By adjusting reaction conditions and adding specific compounds, the morphology and size of LDH can be controlled. The addition of formamide inhibits the formation of byproducts and reduces the size of LDH nanosheets. NaNO3 improves the monodispersity of LDH nanosheets. Lower standard molar Gibbs free energy leads to larger nanosheets using high saturation co-precipitation method, while the alteration of M2+ shows negligible difference in size and shape using homogeneous co-precipitation method.
Article
Biochemistry & Molecular Biology
Zhaoyun Liu, Xi Wang, Chen Zhang, Kui Lin, Jian Yang, Yi Zhang, Jia Hao, Fei Tian
Summary: The development of multifunctional magnetic nanocomposites for cancer therapy is highly desirable in nanomedicine. In this study, a novel nanocomposite FA-BSA/Fe3O4@LDH was developed for the delivery of 5-Fluorouracil. The nanocomposite showed good dispersibility, magnetic property, and pH-responsive drug release. It exhibited excellent anti-cancer cell activity and specific targeting ability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Chemistry, Physical
Junfeng Chen, Liting Jiang, Jiaqi Yang, Xuemei Wang, Ying An, Daoxin Yang, Qingying Wei, Yongle Wang, Renjun Wang, Yuewei Yang, Yanyan Liu
Summary: The CNT/NiCoAl-LDH nanocomposite was successfully prepared and exhibited excellent catalytic performance for the oxygen reduction reaction in MFC cathode. It showed high output voltage, maximum power density, and voltage stabilization time, indicating its potential as a cost-effective catalyst for future high-performance MFC cathodes.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Crystallography
Rodica-Mariana Ion, Claudiu Eduard Rizescu, Dan Adrian Vasile, Gabriel Vasilievici, Irina Atkinson, Adriana Rusu, Luminita Predoana, Florin Miculescu
Summary: Stone monuments suffering from aging and loss of properties can be improved with LDHs treatment, with brushing application being more effective than incorporation.
Article
Chemistry, Multidisciplinary
Wenhui Wang, See Wee Chee, Hongwei Yan, Ivan Erofeev, Utkur Mirsaidov
Summary: The growth pathways of LDH nanosheets can be controlled by tuning precursor concentrations, and they mainly grow through monomer addition and coalescence.
Article
Chemistry, Physical
Litao Wu, Hua Pan, Weilan Huang, Zhongxuan Hu, Meijing Wang, Fang Zhang
Summary: In this study, Prochloraz controlled-release nanoparticles based on bimodal mesoporous silica with redox and pH dual responses were successfully prepared. The nanoparticles showed excellent release performance under acidic conditions, good antifungal activity, and benign biosafety. This work provides a promising approach to improving the efficient utilization of pesticides and reducing environmental pollution.
Article
Chemistry, Multidisciplinary
Qinrui Fu, Hongjuan Feng, Lichao Su, Xuan Zhang, Luntao Liu, Fengfu Fu, Huanghao Yang, Jibin Song
Summary: The study developed a caspase-3 activated nanoprobe for early evaluation of radiotherapy efficacy. The nanoprobe connected nanogapped gold nanoparticles and near-infrared fluorescent molecules through a specific peptide sequence, showing a positive correlation between activated caspase-3 and imaging signals variation and tumor inhibition rate.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Xiangjun Mu, Wanqing Zhang, Changqing Yi, Mei-Jin Li, Fengfu Fu
Summary: In this study, three iridium(III) complexes were designed and synthesized as specific probes for the detection of homocysteine. The photodynamic therapy properties of these complexes were also evaluated, showing promising results for potential applications in photodynamic therapy and homocysteine detection.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Rongjing Hu, Tianmin Guo, Chenyi Zeng, Mingming Chen, Xiajun Zhu, Lichan Chen, Yongqiang Dong, FengFu Fu
Summary: Carbon-based dot-capped gold nanoparticles (AuNPs/CDs) were synthesized and hybridized with folic acid (FA)-modified and CD-capped manganese dioxide nanosheets (FA/MnO2/CDs), resulting in nanohybrids with high singlet oxygen generation capability. The nanohybrids can release oxygen molecules under laser irradiation, relieving tumor hypoxia and effectively killing cancer cells, making them promising for photodynamic therapy applications.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Spectroscopy
Zhiqiang Chen, Wenchao Lv, Chen Yang, Meiling Ping, FengFu Fu
Summary: Free copper ions have critical toxicity to cells, and it is important to develop sensitive monitoring methods. This study designed a ssDNA sequence for synthesizing silver nanoclusters and demonstrated that Cu+/Cu2+ can induce their aggregation and greatly enhance fluorescence emission. Based on this, a fluorescent sensing platform was developed for the detection of Cu+/Cu2+ in biological samples and intracellular imaging, with advantages of rapid detection, simplicity, high sensitivity, good cell permeability, and biocompatibility.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Nanoscience & Nanotechnology
Jingru Chen, Dongshen Zhou, Zhifeng Chen, Xueting Liu, Yuanteng Xu, Liangqia Guo
Summary: Two-dimensional nanomaterials are commonly used as quenching platforms for fluorescently labeled oligonucleotides in biosensor design. However, polymeric carbon nitride nanosheets were found to enhance the fluorescence of tetramethylrhodamine-labeled single-stranded DNA. The enhancement effect was not observed for other fluorophores or nanomaterials. This fluorescence enhancement, attributed to steric hindrance effect, was utilized for sensitive fluorescence detection of single-stranded DNA and microRNA.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Chen Mingming, Su Bihang, Huang Jianli, Fu Fengfu, Dong Yongqiang
Summary: Fungal toxins, a threat to food safety, can be rapidly screened and detected using a simple, rapid, and sensitive surface-enhanced Raman scattering (SERS) technique based on hydrogel SERS chips. The laboratory-constructed hydrogel SERS chips show excellent potential for the rapid screening and detection of biotoxins in food.
CHINESE JOURNAL OF CHROMATOGRAPHY
(2022)
Article
Chemistry, Analytical
Xu Zhang, Chaochen Sun, Ruiling Li, Yongning Wu, Xin Jin, FengFu Fu
Summary: This study presents a reusable magnetic enzyme-loading nanoplatform with enhanced peroxidase-like activity for developing colorimetric sensors. It demonstrates stable and enhanced peroxidase-like activity, good enzyme-loading capacity, and magnetic separation capability, which enables the fabrication of sensitive and simple colorimetric sensors. It also successfully detects glucose and cholesterol with high recovery and low relative standard deviation.
ANALYTICAL CHEMISTRY
(2023)
Article
Electrochemistry
Xiaolong Fu, Ju Huang, Xiaojing Lai, Jiefeng Rong, Guomin Qi, Zhenyu Lin, Fengfu Fu, Yongqiang Dong
Summary: Electrochemiluminescence (ECL) of graphitic carbon nitride nanosheets (CNNSs) has gained extensive interest, but the poor ECL stability of CNNSs has hindered its application. This study investigates the mechanism affecting ECL stability and proposes effective methods to improve it.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Qian Chen, Yuquan Pan, Chaochen Sun, Zongwen Wang, Yongning Wu, FengFu Fu
Summary: To avoid drug resistance, different sulfonamides (SAs) were used alternately in animal husbandry. Therefore, developing simple and high-throughput methods for detecting multiple or groups of SAs is crucial for rapid screening of total SAs residues in foods. In this study, a sensitive and efficient immunosensor using AuNBPs and broad-specificity anti-SAs antibody was developed for the visual screening/semi-quantitative detection of 6 different SAs. The immunosensor showed excellent specificity, low visual detection limit, and can be applied in milk with high recovery rate.
Article
Materials Science, Multidisciplinary
Mingming Chen, Zhihong Liu, Bihang Su, Rongjing Hu, Fengfu Fu, Xiancai Jiang, Zhenyu Lin, Yongqiang Dong
Summary: Hydrogel surface-enhanced Raman scattering (SERS) chips with tunable localized surface plasmon resonance (LSPR) wavelength are prepared to coordinate the chemical enhancement (CM) and electromagnetic enhancement (EM) effects for molecules. The hydrogel SERS chips show outstanding activity to many molecules, providing an efficient strategy for building high-performance SERS substrates.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Physical
Chunqiu Xia, Lanlan Xu, Zhihong Li, Liangqia Guo
Summary: MoS2 nanosheets with sulfur defects were prepared and found to possess peroxidase-like activity, which can be used for colorimetric detection.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu
Summary: It is crucial to develop simple and high-throughput methods for detecting sulfonamides (SAs) due to their widespread use in animal husbandry and aquaculture. In this study, a paper-based multicolor colorimetric aptasensor was developed to detect three specific SAs. The aptasensor showed higher sensitivity, better specificity, and stability, and it was successfully used for the rapid screening of total SA residue in seafood.
Article
Chemistry, Multidisciplinary
Xiaolong Fu, Ju Huang, Xiajun Zhu, Jiefeng Rong, Zhenyu Lin, Yongqiang Dong, Fengfu Fu
Summary: This study systematically investigates luminescent molybdenum disulfide quantum dots (MoS2 QDs) for the first time and finds that the reported blue fluorescence of MoS2 QDs mainly comes from co-existing carbon-based dots rather than MoS2 itself. Additionally, the band gap of MoS2 is independent of its lateral size, making it impossible to obtain luminescent MoS2 QDs by reducing the lateral size.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Jiaxin Zhang, Xiajun Zhu, Mingming Chen, Tianwen Chen, Zhihong Liu, Jianli Huang, Fengfu Fu, Zhenyu Lin, Yongqiang Dong
Summary: This study overcomes the reliability issue of SERS in quantitative analysis by preparing a novel hydrogel SERS chip, which exhibits advantages such as high sensitivity, good repeatability, long-term stability, and anti-interference ability.
Article
Materials Science, Multidisciplinary
Shanshan Xing, Chunqiu Xia, Xinyi Liu, Liangqia Guo, Fengfu Fu
Summary: A simple and green one-step method for exfoliation and functionalization of MoS2 nanosheets was developed, achieving high stability and adsorption capacity for Hg2+. The MoS2 nanosheets showed potential application for biological detoxification.
MATERIALS ADVANCES
(2022)
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
