Article
Environmental Sciences
M. A. R. Sarker, Young-Ho Ahn
Summary: In this study, unique CdO nanoparticles were synthesized using a facile hydrothermal method and investigated for their photocatalytic control of pharmaceutical micropollutants in water and wastewater environments. The CdO nanoparticles exhibited excellent photocatalytic activity under visible LED light irradiation and effectively degraded antibiotics and inactivated multidrug-resistant bacteria.
Article
Microbiology
Xi-kang Tang, Yu-bin Su, Hui-qing Ye, Zhen-yuan Dai, Huan Yi, Ke-xin Yang, Tian-tuo Zhang, Zhuang-gui Chen
Summary: Reprogramming metabolomics was used to study the mechanism of drug resistance in Pseudomonas aeruginosa and revealed that reduced glucose uptake is a key factor leading to decreased intracellular glucose. Exogenous glucose can restore the reduced glucose by activating glucose transport, and enhance the bactericidal effect of antibiotics.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Chemistry, Organic
Haonan Liu, Yueyong Chen, Deng An, Xun Zhang, Saihu Liao
Summary: This study demonstrates the effective photoacid catalytic activity of appropriately substituted 1,1'-bi-2-naphthols (BINOLs) for the acetalization of enol ethers with alcohols under visible light irradiation. The reactions proceed efficiently with a wide range of substrates under mild, near neutral conditions.
Article
Nanoscience & Nanotechnology
Tomas Javorskis, Tomas Rakickas, Alberta Jankunaite, Sarunas Vaitekonis, Arturas Ulcinas, Edvinas Orentas
Summary: We present a simple method for creating large-area, microscale resolution patterns of functional amines on self-assembled monolayers using a photoacid-enriched elastomeric stamp. The limited diffusion of the photoactivated acid enables confined deprotection of N-Boc amino groups to narrow line widths. The experimental setup is based on a conventional HD-DVD optical pickup, making it cost-efficient and maskless.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Ya-Qi Zhu, Wei-Qiang Huang, Guang Chen, Lei Xia, Ye-Zi You, Yue Yu
Summary: Researchers have developed a novel gel that can capture and trap bacteria, preventing their invasion, and the gel has the ability to generate reactive oxygen species (ROS) that can effectively kill bacteria. Experimental results have shown that this gel can accelerate the healing of infected wounds.
Article
Chemistry, Multidisciplinary
Ghadir Ali, Aftab Khan, Asim Shahzad, Aiyeshah Alhodaib, Muhammad Qasim, Iffat Naz, Abdul Rehman
Summary: This study synthesized silver nanoparticles (AgNPs) using extracts from Persicaria hydropiper and found that the synthesized AgNPs enhanced the efficacy of antibiotics against multidrug-resistant bacteria. This research provides a new treatment approach for infectious diseases caused by drug-resistant bacteria.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Peihong Xiao, Zipeng Shen, Deliang Wang, Yinzhen Pan, Ying Li, Junyi Gong, Lei Wang, Dong Wang, Ben Zhong Tang
Summary: A series of near-infrared anion-pi(+) photosensitizers with aggregation-induced emission were designed and developed for broad-spectrum MDR bacteria eradication, achieving up to 99% photodynamic killing efficacy against MRSA and MDR E. coli. Due to enhanced ROS generation capability, these AIE-PSs exhibited excellent therapeutic performance under white light irradiation.
Review
Chemistry, Multidisciplinary
Alexey A. Festa, Olga A. Storozhenko, Leonid G. Voskressensky, Erik V. van der Eycken
Summary: The use of visible light-promoted chemistry in halogenation and halofunctionalisation reactions has significant impact.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Chemistry, Organic
Jitender Singh, Anoop Sharma, Anuj Sharma
Summary: Allenes are attractive molecules for the synthesis of bioactive compounds and naturally occurring products. In recent years, visible light mediated photoredox catalysis has emerged as a powerful method for the functionalization of allenes, contributing significantly to the field.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Review
Chemistry, Organic
Ajay Kumar Dhiya, Aparna Monga, Anuj Sharma
Summary: Quinolines are widely used in various fields, but traditional synthesis methods have drawbacks, prompting the shift towards light-catalyzed synthesis. This review focuses on recent research on the synthesis of quinolines using visible light.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Review
Chemistry, Applied
Jitender Singh, Anuj Sharma
Summary: Functionalized oxindoles are important heterocyclic structures found in many natural products and are key intermediates in drug synthesis. Visible light mediated methodologies for the synthesis of oxindoles have received significant attention and show promise for future applications.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Ying Li, Fei Liu, Jiangjiang Zhang, Xiaoye Liu, Peihong Xiao, Haotian Bai, Shang Chen, Dong Wang, Simon H. P. Sung, Ryan T. K. Kwok, Jianzhong Shen, Kui Zhu, Ben Zhong Tang
Summary: Infected cells acting as Trojan horses protect bacteria and increase pathogen dissemination; AIEgens have broad-spectrum bactericidal activity against MDR bacteria and activate cellular autophagy.
Article
Chemistry, Physical
Juan Du, Xinyue Bai, Simiao Wang, Chunmei Li, Enwei Zhu, Chunbo Liu, Chunhong Ma, Haiyong Guo
Summary: Photocatalytic antibacterial method is an effective and green approach for treating multidrug resistant bacteria infections. In this study, a new organic-conjugated-polymer photocatalyst was synthesized, showing high antimicrobial efficiency against MRSA, S. epidermidis, and E. coli under LED white light. Furthermore, the photocatalyst demonstrated satisfactory stability and excellent photocatalytic activity after recycling processes.
Article
Food Science & Technology
Winnie Mukuna, Abdullah Ibn Mafiz, Bharat Pokharel, Aniume Tobenna, Agnes Kilonzo-Nthenge
Summary: The study investigated the antimicrobial resistance of bacteria isolated from non-dairy milk alternatives, revealing that these substitutes may serve as reservoirs for multidrug-resistant opportunistic pathogens.
Article
Engineering, Environmental
Mohamed Fouad, Mohamed Gar Alalm, Hisham Kh El-Etriby, Daria Camilla Boffito, Shinichi Ookawara, Teruhisa Ohno, Manabu Fujii
Summary: The study utilized ruthenium to enhance the photocatalytic activity of a WO3/ZrO2 composite, resulting in successful disinfection of raw surface waters collected from the Nile Delta region in Egypt. The Ru/WO3/ZrO2 composite showed superior bacterial deactivation compared to the benchmark S-TiO2, with good resistance against inhibition by natural organic matter, indicating potential practical applications.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Liu Wang, Kang Wang, Xiaohui Wang, Ruyan Niu, Xiaohui Chen, Ying Zhu, Zixin Sun, Jichun Yang, Guoxiang Liu, Yang Luo
Summary: In this study, tumor-specific fluorescence imaging was achieved by using intelligent dual-lock DNA automatons, which recognized specific molecular targets on tumor cells. The feasibility and specificity of this approach were validated in vivo with tumor-bearing mice. This work highlights the potential of the proposed IDEA strategy for tumor-specific imaging, paving the way for successful precision diagnosis and treatment.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Medicine, General & Internal
Heng Li, Qi-Zhao Huang, Hong Zhang, Zhen-Xing Liu, Xiao-Hui Chen, Li-Lin Ye, Yang Luo
Summary: Monkeypox is a zoonotic disease caused by the monkeypox virus, and it has become a major public health threat. The immune response to the virus plays a crucial role in disease pathogenesis and clinical manifestations, leading to skin lesions, sepsis, respiratory disease, and damage to immune organs. The immunopathogenesis of monkeypox involves impaired NK-cell function, immune evasion, cytokine storm, and antibody-dependent enhancement, among other factors. Understanding the immunopathology of monkeypox is important for developing immunotherapeutic strategies against the disease.
Review
Engineering, Biomedical
Xiaohui Wang, Hong Zhang, Xiaohui Chen, Chunrong Wu, Ke Ding, Guiyin Sun, Yang Luo, Debing Xiang
Summary: Various types of nanoparticles are utilized to achieve targeted delivery of anticancer drugs, improve efficacy, and reduce side effects. However, their therapeutic effects are not ideal due to tumor microenvironment abnormalities and nanoparticle properties. This review comprehensively discusses the factors hindering nanoparticle penetration into tumors and describes methods for improving nanoparticle distribution. Furthermore, it critically analyzes the future development of nanodrug delivery in oncology.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Multidisciplinary
Uvinduni I. Premadasa, Vera Bocharova, Audrey R. Miles, Diana Stamberga, Stella Belony, Vyacheslav S. Bryantsev, Adnan Elgattar, Yi Liao, Joshua T. Damron, Michelle K. Kidder, Benjamin Doughty, Radu Custelcean, Ying-Zhong Ma
Summary: One of the challenges in current DAC technologies is the high energy cost for sorbent regeneration and CO2 release, making large-scale deployment economically unfeasible. In this study, a photochemically-driven approach using a unique photoacid was developed for CO2 release in DAC systems. The results showed that under light irradiation, a significant conversion of total inorganic carbon to CO2 was achieved, confirming the feasibility of energy-efficient CO2 release using light instead of heat.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Electrical & Electronic
Sooraj Sanjay, Fahimul Islam Sakib, Mainul Hossain, Navakanta Bhat
Summary: In this study, an ultra-scalable, highly sensitive, and label-free pH sensor was proposed by incorporating a negative capacitance (NC) effect with a 2-D WSe2/MoS2 heterostructure-based ion-sensitive field effect transistor (ISFET). The sensor showed a maximum voltage sensitivity of 4.38 V/pH and an enhanced resolution of 0.002 units of pH. Compared to WSe2/MoS2 and NC-WSe2 baseline ISFET counterparts, the NC-WSe2/MoS2-ISFET demonstrated approximately 15x and 8x improvement in sensitivity, respectively. The device design using a 2-D heterostructure ISFET with the NC effect opens up possibilities for highly sensitive and label-free biosensors for point-of-care diagnostics.
IEEE SENSORS JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Bipin Saha, Bipanko Kumar Mondal, Shaikh Khaled Mostaque, Mainul Hossain, Jaker Hossain
Summary: Ternary chalcostibite copper antimony selenide (CuSbSe2) has potential as an absorber for thin film solar cells due to its non-toxic nature, abundance, low-cost fabrication technique, optimum bandgap, and high optical absorption coefficient. A dual-heterojunction n-ZnSe/p-CuSbSe2/p(+)-copper gallium selenide (CGS) solar device is proposed, with CGS as the back surface field (BSF) layer. Numerical simulations show a significantly higher power conversion efficiency (PCE) of 43.77% compared to a single heterojunction counterpart, demonstrating the capability of approaching the detailed balance efficiency limit.
Article
Engineering, Biomedical
Zixin Sun, Xiaohui Chen, Ruyan Niu, Hengyi Chen, Ying Zhu, Chong Zhang, Liu Wang, Huaming Mou, Hong Zhang, Yang Luo
Summary: This study developed a Liposome Fusogenic Enzyme-free circuit (LIFE) approach that enables accurate identification of single exosomal inclusions without destroying the vesicle integrity. The probe-loaded cationic fusogenic liposome can capture and fuse with a target exosome, allowing for probes delivery and target biomolecule-initiated cascaded signal amplification. By controlling the ratio of the introduced LIFE probe, trace cargoes in a single exosome can be accurately determined, paving the way for a universal sensing platform to assess exosomal cargoes for early disease diagnosis and personalized treatment.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Analytical
Ruyan Niu, Xiaohui Chen, Zixin Sun, Liu Wang, Zining Wang, Chong Zhang, Dan Ding, Jichun Yang, Yongzhong Wang, Yang Luo
Summary: Cancer-derived small extracellular vesicles (csEVs) are important indicators for the presence and progression of malignancies, but discriminating csEVs from normal sEVs and detecting them at low abundance in early-stage cancer is challenging. In this study, the researchers developed a TESTER strategy based on MNAzyme-controlled recognition to selectively identify csEVs from complex clinical samples. The TESTER approach achieved highly sensitive and selective quantification of csEVs with a detection threshold of 72 particles/μL, and the researchers also constructed a new platform for bimolecular simultaneous recognition, providing insights for future development of bimolecular-activated detection switches.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Osamah Alghazwat, Adnan Elgattar, Yi Liao
Summary: Carbon dioxide (CO2), the main greenhouse gas causing global warming, can be captured and released repeatedly using a photoacid mixed with a well-studied amine. The photoacid's structural design allows for the tuning of its photoactivity, acidity, and solubility, resulting in efficient CO2 release under moderate visible light irradiation.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Article
Chemistry, Physical
Ya-Nan Yuan, Gao-Jie Yan, Zi-Xuan Wang, Yao-Yao Song, Zhao-Yang Wang, Qing-Lun Wang, Chun Yang, Yi Liao
Summary: This study demonstrates that inclusion complexes of the photoacid MCH1 with cyclodextrins can enhance acidity and chemical stability. The addition of cyclodextrins also slows the thermal relaxation of the photoacid and increases its half-life in aqueous solution.
Article
Chemistry, Multidisciplinary
Yeasin Arafat Pritom, Dipayon Kumar Sikder, Sameia Zaman, Mainul Hossain
Summary: In this study, the light absorption properties of sub-wavelength plasmonic nanostructures decorated with metallic nanoparticles are demonstrated. The parabolic shape of the nanostructures provides excellent antireflection effects, while the metallic nanoparticles offer broadband absorption and high conversion efficiency. The proposed solar cell shows a power conversion efficiency as high as 21.39%, making it a promising candidate for the next generation of highly efficient, ultra-thin, and low-cost Si solar cells.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Multidisciplinary
Muhammad Aminul Haque Chowdhury, Nishat Tasnim, Mainul Hossain, Ahsan Habib
Summary: The development of wearable sensors has revolutionized remote patient monitoring and personalized medicine. This paper proposes a novel wearable device, a flexible, stretchable, and single-molecule-sensitive SERS-active sensor, which offers unprecedented SERS enhancement factor, high scattering to absorption ratio, and large hotspot volume. The sensor is made flexible with the use of polydimethylsiloxane (PDMS) as the substrate, and it shows reliable SERS performance even under bending or stretching. The easy fabrication and flexibility of the sensor offer promising opportunities for developing highly sensitive wearable sensors, particularly in the field of personalized medicine and remote patient monitoring.
Article
Chemistry, Analytical
Hengyi Chen, Xiaohui Chen, Yi Chen, Chong Zhang, Zixin Sun, Jiaxi Mo, Yongzhong Wang, Jichun Yang, Dongsheng Zou, Yang Luo
Summary: In this study, a bioorthogonal approach towards high-fidelity imaging of intracellular miRNA was proposed. A multifunctional nanoprobe was designed to integrate MnO2 nanosheet-mediated delivery and activation by FTO-switched positive feedback. This strategy realized high-fidelity imaging of intracellular aberrant miRNA within tumor cells with a satisfactory detection limit, paving the way to facilitate clinical tumor diagnosis and prognosis monitoring.
Article
Energy & Fuels
Md Jayed Hossain, Tasnia Jahan, Jaker Hossain, Mainul Hossain
Summary: Numerical simulations were used to evaluate the performance of a novel all-inorganic tandem solar cell using antimony (Sb) based compound semiconductors as absorber layers. The optimized cell achieved high open circuit voltage and power conversion efficiency.
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2023)
Article
Chemistry, Multidisciplinary
Yeasin Arafat Pritom, Dipayon Kumar Sikder, Sameia Zaman, Mainul Hossain
Summary: In this study, we used metallic gold nanoparticles to enhance the light absorption of ultra-thin silicon solar cells. Through simulations, we showed that the combination of periodic and parabola shaped silicon nanostructures, along with the decoration of gold nanoparticles, can significantly improve the absorption efficiency of the solar cells. The results suggest that this approach has the potential to achieve a high conversion efficiency of 21.39%.
NANOSCALE ADVANCES
(2023)
Article
Materials Science, Biomaterials
Izabela Stupka, Artur P. Biela, Bernard Piette, Agnieszka Kowalczyk, Karolina Majsterkiewicz, Kinga Borzecka-Solarz, Antonina Naskalska, Jonathan G. Heddle
Summary: Artificial protein cages, such as TRAP-cages, have potential applications in vaccines and drug delivery. TRAP-cages have the ability to control the disassembly conditions by modifying the interface between their building blocks. By using TRAP rings with different numbers of monomers, it is possible to predict the formation of other cages.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Guo Zhang, Yu Wang, Hua Qiu, Lei Lu
Summary: This study presents a one-pot synthesis method for flower-like AMPs@EAMP particles by combining antimicrobial peptides with ellagic acid, offering enlarged surface area, excellent biocompatibility, and broad-spectrum antibacterial activity. In vivo studies indicate their potential for tissue repair and immune barrier reconstruction.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Jiamei Zhang, Lingshuang Wang, Cheng Xu, Yingui Cao, Shengsheng Liu, Rui L. Reis, Subhas C. Kundu, Xiao Yang, Bo Xiao, Lian Duan
Summary: Pluronic F127 modified silk fibroin film with different types of antibacterial agents could accelerate wound recovery by promoting fibroblast adhesion, eradicating bacteria, and facilitating angiogenesis and re-epithelialization.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Article
Materials Science, Biomaterials
Yinsheng Liu, Mingyue Wang, Yinfei Hui, Lei Sun, Yanrui Hao, Henlong Ren, Hao Guo, Wu Yang
Summary: In this study, a rare-earth hybrid luminescent material was developed for the detection of a biomarker for anthrax. The material showed excellent selectivity and high sensitivity, allowing for the determination of the biomarker in saliva and urine. Additionally, a convenient point-of-care testing method using fluorescent test paper and a smartphone was established for the initial diagnosis of anthrax.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
Review
Materials Science, Biomaterials
Wenshuai Yang, Jingsi Chen, Ziqian Zhao, Meng Wu, Lu Gong, Yimei Sun, Charley Huang, Bin Yan, Hongbo Zeng
Summary: Injectable hydrogels with shear-thinning and/or in situ formation properties offer distinct advantages in bioengineering applications, as they can be directly delivered to target sites, possess self-healing abilities, and simplify the implantation process.
JOURNAL OF MATERIALS CHEMISTRY B
(2024)
