Sequential thermo-induced self-gelation and acid-triggered self-release process of drug-conjugated nanoparticles: a strategy for the sustained and controlled drug delivery to tumors

Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection

(2012) Zeyu Xiao et al.   ACS Nano

Adjustable degradation and drug release of a thermosensitive hydrogel based on a pendant cyclic ether modified poly(ε-caprolactone) and poly(ethylene glycol)co-polymer

(2012) Weiwei Wang et al.   Acta Biomaterialia

Templated Assembly of pH-Labile Polymer-Drug Particles for Intracellular Drug Delivery

(2012) Jiwei Cui et al.   ADVANCED FUNCTIONAL MATERIALS

Hydrogels for Protein Delivery

(2012) Tina Vermonden et al.   CHEMICAL REVIEWS

Targeting and anti-tumor effect of folic acid-labeled polymer–Doxorubicin conjugates with pH-sensitive hydrazone linker

(2012) Xiuli Hu et al.   JOURNAL OF MATERIALS CHEMISTRY

Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites

(2012) ChangYang Gong et al.   Nanoscale

Thermosensitive in situ hydrogel of paclitaxel conjugated poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)

(2012) Xiaona Lin et al.   Soft Matter

Nanospheres-Incorporated Implantable Hydrogel as a Trans-Tissue Drug Delivery System

(2011) Dan Ding et al.   ACS Nano

Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery

(2011) Xian-Zhu Yang et al.   ACS Nano

Evolution-Based Design of an Injectable Hydrogel

(2011) Iris M. Geisler et al.   ADVANCED FUNCTIONAL MATERIALS

In vivo efficacy of an intratumorally injected in situ-forming doxorubicin/poly(ethylene glycol)-b-polycaprolactone diblock copolymer

(2011) Yun Mi Kang et al.   BIOMATERIALS

Biodegradable polymer − cisplatin(IV) conjugate as a pro-drug of cisplatin(II)

(2011) Haihua Xiao et al.   BIOMATERIALS

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Trigger-responsive nanoparticles: control switches for cancer therapy

(2011) Rinti Banerjee   Nanomedicine

Controlled thermal gelation of poly(ε-caprolactone)/poly(ethylene glycol) block copolymers by modifying cyclic ether pendant groups on poly(ε-caprolactone)

(2011) Weiwei Wang et al.   Soft Matter

Design of Multiresponsive Hydrogel Particles and Assemblies

(2010) Grant R. Hendrickson et al.   ADVANCED FUNCTIONAL MATERIALS

Dual Stimuli-Responsive Supramolecular Polypeptide-Based Hydrogel and Reverse Micellar Hydrogel Mediated by Host-Guest Chemistry

(2010) Yi Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Intracellular pH-Responsive Mesoporous Silica Nanoparticles for the Controlled Release of Anticancer Chemotherapeutics

(2010) Chia-Hung Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biodegradable Block Copolymer-Doxorubicin Conjugates via Different Linkages: Preparation, Characterization, and In Vitro Evaluation

(2010) Xiuli Hu et al.   BIOMACROMOLECULES

Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds

(2010) Yuguo Lei et al.   BIOMATERIALS

In vivo efficacy of paclitaxel-loaded injectable in situ-forming gel against subcutaneous tumor growth

(2010) Ju Young Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A duplex oligodeoxynucleotide–dendrimer bioconjugate as a novel delivery vehicle for doxorubicin in in vivo cancer therapy

(2010) In-Hyun Lee et al.   JOURNAL OF CONTROLLED RELEASE

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL–PEG–PCL hydrogel. Part 2: Sol–gel–sol transition and drug delivery behavior

(2009) ChangYang Gong et al.   Acta Biomaterialia

Doxorubicin-Conjugated Immuno-Nanoparticles for Intracellular Anticancer Drug Delivery

(2009) Meng Shi et al.   ADVANCED FUNCTIONAL MATERIALS

Phase 2: a dose-escalation study of OncoGel (ReGel/paclitaxel), a controlled-release formulation of paclitaxel, as adjunctive local therapy to external-beam radiation in patients with inoperable esophageal cancer

(2009) G. Aaron DuVall et al.   ANTI-CANCER DRUGS

Doxorubicin–polyphosphazene conjugate hydrogels for locally controlled delivery of cancer therapeutics

(2009) ChangJu Chun et al.   BIOMATERIALS

Thermosensitive poly(organophosphazene)–paclitaxel conjugate gels for antitumor applications

(2009) ChangJu Chun et al.   BIOMATERIALS

The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents

(2009) Gaurav Sahay et al.   BIOMATERIALS

The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin

(2009) Xiao-Bing Xiong et al.   BIOMATERIALS

Biodegradable amphiphilic polymer–drug conjugate micelles

(2009) Xiuli Hu et al.   Expert Opinion on Drug Delivery

Pharmacokinetics of doxorubicin after intratumoral injection using a thermosensitive hydrogel in tumor-bearing mice

(2009) Ahmed M. Al-Abd et al.   JOURNAL OF CONTROLLED RELEASE

Doxorubicin conjugated gold nanoparticles as water-soluble and pH-responsive anticancer drug nanocarriers

(2009) Santosh Aryal et al.   JOURNAL OF MATERIALS CHEMISTRY

Organic nanoscale drug carriers coupled with ligands for targeted drug delivery in cancer

(2009) Meng Shi et al.   JOURNAL OF MATERIALS CHEMISTRY

Controlled Release of Paclitaxel from Amphiphilic Copolymer Hybrid Assembly Nanoparticles

(2009) Na Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Hydrogel nanoparticles in drug delivery

(2008) Mehrdad Hamidi et al.   ADVANCED DRUG DELIVERY REVIEWS

Doxorubicin conjugated to d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS): Conjugation chemistry, characterization, in vitro and in vivo evaluation

(2008) Na Cao et al.   BIOMATERIALS

Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin

(2008) Kenji Kono et al.   BIOMATERIALS

Development of novel polymeric micellar drug conjugates and nano-containers with hydrolyzable core structure for doxorubicin delivery

(2008) A MAHMUD et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

(2008) Chaoliang He et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Multifunctional Polymeric Micelles for Enhanced Intracellular Delivery of Doxorubicin to Metastatic Cancer Cells

(2008) Xiao-Bing Xiong et al.   PHARMACEUTICAL RESEARCH

Hydrogels in drug delivery: Progress and challenges

(2008) Todd R. Hoare et al.   POLYMER