Article
Cardiac & Cardiovascular Systems
Michel Pompeu Sa, Jef Van den Eynde, Matheus Simonato, Sameer Hirji, Ozgun Erten, Xander Jacquemyn, Panagiotis Tasoudis, Alexander Dokollari, Serge Sicouri, Alexander Weymann, Arjang Ruhparwar, Rakesh Arora, Marie- Annick Clavel, Philippe Pibarot, Basel Ramlawi
Summary: The study found that ViV-TAVI is associated with a decreased risk of all-cause mortality in the short term after the procedure compared to redo SAVR. However, over time, redo SAVR seems to be protective against all-cause mortality. These results should be interpreted with caution as they are based on pooled data from observational studies, and further clinical trials are needed.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Hematology
Brandon G. Shokoples, Pierre Paradis, Ernesto L. Schiffrin
Summary: Chronic low-grade inflammation is closely linked to cardiovascular diseases. Targeting the purinergic receptor P2X7, which mediates inflammation and cellular death, shows potential in mitigating cardiovascular conditions. Inhibiting P2X7 activation and IL-1 beta/IL-18 release may reduce cardiovascular disease severity and occurrence of adverse cardiac events.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yi-Xin Wang, Mariel Arvizu, Janet W. Rich-Edwards, Liang Wang, Bernard Rosner, Jennifer J. Stuart, Kathryn M. Rexrode, Jorge E. Chavarro
Summary: The study found that experiencing hypertensive disorders of pregnancy (HDPs) such as gestational hypertension or pre-eclampsia is associated with an increased risk of premature mortality, particularly cardiovascular mortality, regardless of developing chronic hypertension later on.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sohyun Chun, Dong Wook Shin, Kyungdo Han, Jin Hyung Jung, Bongseong Kim, Hee-Won Jung, Ki Young Son, Seung-Pyo Lee, Sang Chol Lee
Summary: The study concluded that slower Timed Up and Go test speed is associated with a higher risk of myocardial infarction, congestive heart failure, and mortality in older adults.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Michel Pompeu Sa, Xander Jacquemyn, Jef Van den Eynde, Panagiotis Tasoudis, Aleksander Dokollari, Gianluca Torregrossa, Serge Sicouri, Marie-Annick Clavel, Philippe Pibarot, Basel Ramlawi
Summary: Severe prosthesis-patient mismatch (PPM) is associated with increased risk of mortality following transcatheter aortic valve replacement (TAVR). Preventive strategies should be implemented to avoid severe PPM.
JACC-CARDIOVASCULAR IMAGING
(2022)
Review
Cardiac & Cardiovascular Systems
Laura Elizabeth Dobson, Bernard D. Prendergast
Summary: This review article highlights the influential contributions of UK cardiologists and surgeons in the field of heart valve disease, including various groundbreaking innovations. It emphasizes the early adoption of transcatheter aortic valve implantation (TAVI) in the UK and the role of the comprehensive national database in contributing real-world patient data. The article also mentions the development of specialized heart valve clinics and the future potential of artificial intelligence and cutting-edge technology in improving patient care.
Article
Peripheral Vascular Disease
Ramachandran S. Vasan, Stephanie Pan, Vanessa Xanthakis, Alexa Beiser, Martin G. Larson, Sudha Seshadri, Gary F. Mitchell
Summary: This study examines the association between arterial stiffness and various health outcomes, including hypertension, diabetes, chronic kidney disease, dementia, cardiovascular disease, coronary heart disease, stroke, and death. The results show that arterial stiffness is associated with an increased risk of these health outcomes.
Review
Peripheral Vascular Disease
Thomas G. Riemer, Linda E. Villagomez Fuentes, Engi A. E. Algharably, Marie S. Schafer, Eva Mangelsen, Marc-Alexander Furtig, Nadine Bittner, Annalena Bar, Laila Zaidi Touis, Kristian Wachtell, Tomislav Majic, Martin J. Dinges, Reinhold Kreutz
Summary: Analysis of large-scale data from double-blind, randomized controlled trials did not find an association between beta-blocker therapy and depression. Similarly, beta-blockers showed no effect on other psychiatric adverse events, except for a possible link with sleep-related disorders. Therefore, concerns about the impact of beta-blockers on mental health should not affect their clinical use.
Article
Peripheral Vascular Disease
Fergus P. McCarthy, Jamie M. O'Driscoll, Paul T. Seed, Anna Placzek, Carolyn Gill, Jenie Sparkes, Lucilla Poston, Mike Marber, Andrew H. Shennan, Basky Thilaganathan, Paul Leeson, Lucy C. Chappell
Summary: This study found that late preterm preeclampsia can lead to persistence of hypertension in the majority and systolic left ventricular dysfunction in 10% of women 6 months postpartum. Planned early delivery does not affect these outcomes.
Article
Cardiac & Cardiovascular Systems
Nathalie Donis, Zheshen Jiang, Celine D'Emal, Alexia Hulin, Margaux Debuisson, Raluca Dulgheru, Mai-Linh Nguyen, Adriana Postolache, Francois Lallemand, Philippe Coucke, Philippe Martinive, Marielle Herzog, Dorian Pamart, Jason Terrell, Joel Pincemail, Pierre Drion, Philippe Delvenne, Alain Nchimi, Patrizio Lancellotti, Cecile Oury
Summary: The study investigated the effects of dietary cholesterol, palmitic acid, and cardiac irradiation on vascular and valvular lesions in a rabbit model of cardiovascular diseases (CVDs). The results showed that a cholesterol-enriched diet led to aortic wall thickening, immune cell infiltration, and aortic valve calcification, while a lard-enriched diet induced massive aorta and aortic valve calcification without immune cell infiltration. The addition of cardiac irradiation to the cholesterol diet resulted in more calcification and immune cell infiltrates in the atheroma and aortic valve. RNA sequencing analysis revealed that inflammation-related processes were mainly triggered by a cholesterol-enriched diet, which was further enhanced by cardiac irradiation. Lard-enriched diet mainly affected calcification- and muscle-related processes. Early biomarkers of cholesterol-induced tissue alterations were identified, and cardiac irradiation led to elevated levels of circulating nucleosomes. In conclusion, this study highlights the specificities related to common risk factors underlying CVD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Nutrition & Dietetics
Filippo Pirrotta, Guido Cavati, Christian Mingiano, Daniela Merlotti, Ranuccio Nuti, Luigi Gennari, Alberto Palazzuoli
Summary: Vitamin D is important for bone metabolism and plays a role in regulating calcium and phosphate levels in the body. It has been found to have an impact on cardiovascular disease, with evidence of vitamin D receptors in the cardiovascular system. This study examined the relationship between vitamin D levels and hospitalization for heart failure, overall mortality, and cardiovascular mortality.
Article
Cardiac & Cardiovascular Systems
Michel Pompeu Sa, Xander Jacquemyn, Jef Van den Eynde, Panagiotis Tasoudis, Aleksander Dokollari, Gianluca Torregrossa, Serge Sicouri, Marie-Annick Clavel, Philippe Pibarot, Basel Ramlawi
Summary: This study evaluated the time-varying effects and association of prosthesis-patient mismatch (PPM) with the risk of overall mortality following transcatheter aortic valve replacement (TAVR). The results showed that severe PPM was significantly associated with higher mortality risk after TAVR, while moderate PPM did not show a significant correlation with mortality. These findings support the implementation of preventive strategies to avoid severe PPM.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Environmental Sciences
Saeed Motesaddi Zarandi, Mostafa Hadei, Seyed Saeed Hashemi, Elahe Shahhosseini, Philip K. Hopke, Zahra Namvar, Abbas Shahsavani
Summary: Short-term exposure to air pollution is associated with adverse health effects, particularly cardiovascular diseases. This study in Tehran found that ambient air pollutants like CO, SO2, PM2.5, and PM10 were linked to hospital admissions and mortality from CVDs, with females being more vulnerable. Planning and implementing strategies to reduce air pollution are crucial in mitigating the harmful effects of pollutants on public health.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Pharmacology & Pharmacy
M-L Hua, L. Li, L. L. Diao
Summary: Asthma is significantly associated with an increased risk of cardiovascular disease (CVD). Patients with asthma have higher risks of cardiovascular heart disease (CHD), cardiovascular mortality (CVM), heart failure (HF), and myocardial infraction (MI). Active asthmatic patients have a higher risk of atrial fibrillation (AF). Females with asthma have a higher risk of CHD, while active asthmatic patients have a higher risk of CVM.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Michel Pompeu Sa, Xander Jacquemyn, Jef van den Eynde, Derek Serna-Gallegos, Danny Chu, Marie-Annick Clavel, Philippe Pibarot, Ibrahim Sultan
Summary: A meta-analysis of reconstructed time-to-event data from randomized controlled trials and propensity-score matched studies showed that, in low-risk patients, surgical aortic valve replacement (SAVR) appeared to be associated with improved survival beyond 2 years compared to transcatheter aortic valve replacement (TAVR).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Obstetrics & Gynecology
Ibinabo Ibiebele, Tanya A. Nippita, Rodney Baber, Siranda Torvaldsen
Summary: Factors such as nulliparity, older age, marital status, and diagnosis of heavy menstrual bleeding are associated with an increased risk of post-endometrial ablation pregnancy. Post-ablation pregnancies have high rates of cesarean delivery, preterm birth, twin or higher order pregnancies, and stillbirth.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Obstetrics & Gynecology
Ye'elah Berman, Ibinabo Ibiebele, Deborah Randall, Siranda Torvaldsen, Tanya A. Nippita, Jennifer Bowen, Heather J. Baldwin, Stephanie M. Todd, Jonathan M. Morris, Jane B. Ford, Jillian A. Patterson
Summary: Research shows that neonatal morbidity varies by maternal region of birth at different gestational ages. Babies born to East, South-east, and West Asian-born mothers in New South Wales have lower adjusted rates of neonatal morbidity compared to Australian or New Zealand-born mothers, while babies born to Oceanian-born mothers have higher rates. Maternal region of birth is an independent risk factor for neonatal morbidity in the region.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Obstetrics & Gynecology
Jessica Gugusheff, Jillian Patterson, Siranda Torvaidsen, Ibinabo Ibiebele, Tanya Nippita
Summary: This study in New South Wales, Australia, found that having an intrapartum or prelabour caesarean delivery as the first birth increases the risk of subsequent preterm birth, while having a prior instrumental birth reduces the risk of subsequent spontaneous preterm birth but increases the risk of preterm prelabour caesarean delivery. These findings highlight the importance of considering the mode of first birth in clinical decisions related to subsequent pregnancies.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2021)
Article
Obstetrics & Gynecology
Simon West, Ibinabo Ibiebele, Tanya Nippita
Summary: Women who had their first FBS at <4 cm cervical dilation were twice as likely to have a caesarean section compared to women who had their first FBS >= 4 cm. However, 41% had a vaginal birth, and there were no differences in fetal outcomes.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2021)
Article
Obstetrics & Gynecology
Jonathan Sandeford, Tanya Nippita, Tushar Bhuta, Jillian Patterson, Jonathan Morris, Sean Seeho
Summary: This study aims to evaluate the effectiveness of oral probiotic therapy in prolonging pregnancy duration and its impact on maternal and neonatal outcomes in PPROM. The study is a pragmatic, multicenter, double-blind, placebo-controlled randomized controlled trial involving singleton pregnant women with gestational age less than 24 weeks.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2021)
Meeting Abstract
Public, Environmental & Occupational Health
Heather Baldwin, Deborah Randall, Tanya Nippita, Siranda Torvaldsen, Jillian Patterson
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Meeting Abstract
Public, Environmental & Occupational Health
Heather Baldwin, Siranda Torvaldsen, Kristen Rickard, Tanya Nippita, Jillian Patterson
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Meeting Abstract
Public, Environmental & Occupational Health
Jessica Gugusheff, Jillian Patterson, Siranda Torvaldsen, Ibinabo Ibiebele, Tanya Nippita
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Obstetrics & Gynecology
Jillian Patterson, Deborah Randall, James Isbister, Michael Peek, Tanya Nippita, Siranda Torvaldsen
Summary: Guidelines recommend that high-risk postpartum hemorrhage patients give birth in facilities capable of handling heavy bleeding. However, unexpected hemorrhage often occurs. This study compared outcomes and health service use related to transfusion of >= 4 units of red blood cells between women delivering in tertiary and lower level hospitals. The results showed that while women receiving >= 4 units in tertiary settings were more likely to receive other blood products and have longer hospital stays, overall outcomes were comparable between tertiary and non-tertiary facilities.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Rebecca Young, Tanya A. C. Nippita
Summary: This study found variations in training for obstetric anal sphincter injuries (OASIS) in Australia and New Zealand, with trainees gaining increasing confidence in independently repairing OASIS throughout their training. Trainees requested improvements be made to training through an increase in structured teaching.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Edward Jegasothy, Deborah A. Randall, Jane B. Ford, Tanya A. Nippita, Geoffrey G. Morgan
Summary: Exposure to high temperatures increases the risk of preterm birth, especially for women with pre-existing health conditions and who smoke during pregnancy.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Ibinabo Ibiebele, Tanya Nippita, Rodney Baber, Siranda Torvaldsen
Summary: This study found that both endometriosis and the use of assisted reproductive technology (ART) are associated with an increased risk of preterm birth, antepartum hemorrhage, placenta previa, and planned birth (cesarean delivery or induction of labor). These results suggest that women with endometriosis, including those who used ART to achieve pregnancy, are a higher-risk obstetric group requiring appropriate surveillance and management during their pregnancy.
HUMAN REPRODUCTION
(2022)
Article
Health Care Sciences & Services
Jillian A. Patterson, Aaron Cashmore, Sally Ioannides, Andrew J. Milat, Tanya A. Nippita, Jonathan M. Morris, Siranda Torvaldsen
Summary: The study found that not smoking during pregnancy can reduce the risks of adverse pregnancy outcomes for non-Aboriginal mothers and their babies in New South Wales. Additionally, it was also found that not smoking during pregnancy has benefits in reducing the severe morbidity and inter-hospital transfer rates for mothers.
INTERNATIONAL JOURNAL OF POPULATION DATA SCIENCE (IJPDS)
(2021)
Article
Health Care Sciences & Services
Heather J. Baldwin, Tanya A. Nippita, Kristen Rickard, Siranda Torvaldsen, Therese M. McGee, Jillian A. Patterson
Summary: The study found that coded hospital data are reliable sources of information for gestational and pre-existing diabetes, as well as gestational hypertension. Chronic hypertension is reported less consistently, which could be addressed by grouping different types of hypertension. Data on thyroid conditions and morbid obesity should be used cautiously, and alternative data sources should be sought if possible.
INTERNATIONAL JOURNAL OF POPULATION DATA SCIENCE (IJPDS)
(2021)
Article
Biology
Heather J. Baldwin, Tanya A. Nippita, Siranda Torvaldsen, Therese M. McGee, Kristen Rickard, Jillian A. Patterson
Summary: The study found that hospital data may be reliable for information on postpartum hemorrhage, transfusion, and hysterectomy, but caution is needed for studies of anemia and blood disorders due to high rates of uncoded and false cases.
BMC RESEARCH NOTES
(2021)
