Article
Parasitology
Stephanie L. Macdonald, Ghazanfar Abbas, Abdul Ghafar, Charles G. Gauci, Jenni Bauquier, Charles El-Hage, Brett Tennent-Brown, Edwina J. A. Wilkes, Anne Beasley, Caroline Jacobson, Lucy Cudmore, Peter Carrigan, John Hurley, Ian Beveridge, Kristopher J. Hughes, Martin K. Nielsen, Abdul Jabbar
Summary: This paper reviews the available data on the egg reappearance period (ERP) of cyathostomins against the three major classes of anthelmintics. A total of 54 studies met the inclusion criteria for the systematic review. Until 2022, there was no agreed definition of the ERP, and different definitions in the literature complicated the comparison between studies. Future research is needed to understand the mechanism(s) behind the shortening of ERP for cyathostomins.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
(2023)
Article
Agriculture, Dairy & Animal Science
Floriana Sajovitz, Isabella Adduci, Shi Yan, Sandra Wiedermann, Alexander Tichy, Anja Joachim, Thomas Wittek, Barbara Hinney, Katharina Lichtmannsperger
Summary: Gastrointestinal nematodes, particularly trichostrongylids, can cause significant losses in sheep production. This study investigated the correlations between faecal egg counts and clinical parameters in dairy ewes, and found only weak correlations between the two. It also confirmed that a small proportion of the flock is responsible for the majority of pasture contamination with trichostrongylid eggs.
Article
Genetics & Heredity
Jacob W. Thorne, Reid Redden, Scott A. Bowdridge, Gabrielle M. Becker, Morgan R. Stegemiller, Brenda M. Murdoch
Summary: Genome-wide association studies were conducted to identify SNPs associated with the biological response to a GIN infection in lambs. The results showed the importance of immune cell development and mucin production in enhancing sheep resistance to GINs.
Article
Parasitology
S. Luethin, A. Zollinger, W. Basso, M. Bisig, N. Caspari, V. Eng, C. F. Frey, F. Grimm, P. Igel, S. Luthi, W. Regli, L. Roelfstra, M. Rosskopf, B. Steiner, M. Stockli, D. Waidyasekera, P. Waldmeier, M. Schnyder, P. R. Torgerson, H. Hertzberg
Summary: This study retrospectively analyzed fecal egg count data from horses in Switzerland and found that the standard parasite management method has led to an expansion of resistant helminth populations. The study also suggests that the concept of selective anthelmintic treatment can help mitigate the further spread of anthelmintic resistance.
VETERINARY PARASITOLOGY
(2023)
Article
Parasitology
Madeleine Bucki, Kerrie Ni Dhufaigh, Christiane 'Brien, Andrew Weatherley, Nigel Walshe, Tara McElligott
Summary: Traditional blanket treatment for gastrointestinal helminths in grazing livestock has led to resistance to anthelmintic drugs, impacting farm profitability and animal welfare. Faecal egg counts (FECs) are an important diagnostic test to combat anthelmintic resistance. However, FECs are time-consuming and labor-intensive. This study evaluated a rapid on-site parasite diagnostic system using a smartphone app and machine learning, which was found to be non-inferior to the accredited laboratory in quantifying Strongyle eggs in ovine faecal samples.
VETERINARY PARASITOLOGY
(2023)
Review
Parasitology
Eric R. Morgan, Carlos Lanusse, Laura Rinaldi, Johannes Charlier, Jozef Vercruysse
Summary: The increase in anthelmintic resistance in livestock has prompted efforts to monitor anthelmintic effectiveness on farms. However, measuring fecal egg count reduction can be affected by various factors other than anthelmintic resistance. This review discusses confounders of fecal egg count reduction, including host and parasite physiology, pharmacokinetic variation, and technical performance. Understanding these confounders is crucial for accurately assessing anthelmintic efficacy.
Article
Veterinary Sciences
Tim. S. S. Mair, Rebecca Opie, Michelle Moreton-Clack, Tim. D. D. Parkin, Jacqui. B. B. Matthews
Summary: This study aimed to measure the strongyle egg reappearance period (ERP) following moxidectin treatment in horses in southeast England. The results indicated acceptable efficacy of moxidectin at 14 days after treatment, but the group's ERP pattern suggested a considerably shorter suppressive effect compared to when moxidectin was first introduced (12-16 weeks).
EQUINE VETERINARY EDUCATION
(2023)
Article
Parasitology
Jennifer L. Cain, Kerri T. Peters, Parul Suri, Amber Roher, Matthew H. Rutledge, Martin K. Nielsen
Summary: This study examined the variability and precision of analysts in fecal egg counts using automated and manual methods. It found that formal training can reduce analyst variability and increase precision, providing important insights for parasite control programs in veterinary medicine.
PARASITOLOGY RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Maria V. Baranova, Olga A. Panova, Daria N. Polukhina, Daria S. Panova
Summary: The study revealed high rates of nematode infection in horses in the Moscow Region, with Parascaris equorum being the most common. The egg reappearance period indicated the need for additional monitoring of anthelmintic resistance for effective control.
Article
Parasitology
Kaylee Kipp, Daniel B. Cummings, Dan Goehl, H. H. Wade, John M. Davidson, David Renter, Guilherme G. Verocai, Lea Rash
Summary: Refugia-based strategies combined with different classes of anthelmintic drugs are increasingly used to manage anthelmintic resistance in small ruminants. This study aimed to compare the effect of a refugia-based strategy with a whole herd treatment strategy on body weight, average daily gain, and fecal egg counts in naturally infected beef calves.
VETERINARY PARASITOLOGY
(2023)
Article
Multidisciplinary Sciences
Michaela Urda Dolinska, Alzbeta Konigova, Georg von Samson Himmelstjerna, Marian Varady
Summary: We assessed the variation in the frequency of BZ resistance-associated alleles at specific codons of the beta-tubulin 1 gene in susceptible and resistant strains of Haemonchus contortus using pyrosequencing. Our results show significant variation in the frequency of these alleles during the patent period, which should be taken into consideration when testing for BZ resistance in parasite populations.
SCIENTIFIC REPORTS
(2023)
Review
Veterinary Sciences
M. K. Nielsen
Summary: This article discusses the general concepts of evaluating and assessing faecal egg count test performance and addresses common misconceptions. Accuracy and precision are important quantitative parameters that affect strongylid shedding classification and anthelmintic efficacy estimates. Veterinarians should consider the performance of the technique used for faecal egg counts and the training and experience of personnel for diagnostic quality assurance.
EQUINE VETERINARY EDUCATION
(2022)
Article
Parasitology
Neil Sargison, Alex Chambers, Umer Chaudhry, Livio Costa Junior, Stephen R. Doyle, Ajoke Ehimiyein, Mike Evans, Amy Jennings, Rob Kelly, Fiona Sargison, Margaret Sinclair, Osama Zahid
Summary: This study explored the composition and temporal changes of gastrointestinal nematode communities within host species, revealing seasonal trends of strongylid parasites and significant differences in species diversity between horses and months.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2022)
Article
Parasitology
Neil Sargison, Alex Chambers, Umer Chaudhry, Livio Costa Junior, Stephen R. Doyle, Ajoke Ehimiyein, Mike Evans, Amy Jennings, Rob Kelly, Fiona Sargison, Margaret Sinclair, Osama Zahid
Summary: This study used deep sequencing to describe the gastrointestinal nematode communities of Scottish ponies, revealing significant differences in species diversity between seasons and months, as well as changes in parasite abundance over time and across hosts.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2022)
Article
Parasitology
Matthew J. Denwood, Ray M. Kaplan, Iain J. McKendrick, Stig M. Thamsborg, Martin K. Nielsen, Bruno Levecke
Summary: The faecal egg count reduction test (FECRT) is a crucial tool for detecting anthelmintic resistance in livestock. This study provides a comprehensive overview of the quantitative issues involved in FECRT and introduces a new approach for determining sample size requirements. The study also presents a classification system for anthelminthic drug efficacy based on a solid statistical framework. The findings of this study will contribute to the upcoming FECRT WAAVP guidelines and are available as open-source software.
VETERINARY PARASITOLOGY
(2023)
Article
Parasitology
Romain Garnier, Bryan T. Grenfell, Alasdair J. Nisbet, Jacqueline B. Matthews, Andrea L. Graham
Editorial Material
Parasitology
A. J. Trees, D. J. L. Williams, J. B. Matthews
VETERINARY PARASITOLOGY
(2015)
Article
Parasitology
Claire L. McArthur, Ian G. Handel, Ailie Robinson, Jane E. Hodgkinson, Barend MdeC Bronsvoort, Faith Burden, Ray M. Kaplan, Jacqueline B. Matthews
VETERINARY PARASITOLOGY
(2015)
Article
Parasitology
L. E. Peachey, G. L. Pinchbeck, J. B. Matthews, F. A. Burden, G. Mulugeta, C. E. Scantlebury, J. E. Hodgkinson
VETERINARY PARASITOLOGY
(2015)
Editorial Material
Veterinary Sciences
M. K. Nielsen, G. von Samson-Himmelstjerna, K. Pfister, C. R. Reinemeyer, M. B. Molento, A. S. Peregrine, J. E. Hodgkinson, S. Jacobsen, R. M. Kaplan, J. B. Matthews
EQUINE VETERINARY JOURNAL
(2016)
Review
Immunology
J. B. Matthews, P. Geldhof, T. Tzelos, E. Claerebout
PARASITE IMMUNOLOGY
(2016)
Article
Parasitology
Mairi C. Mitchell, Thomas Tzelos, Ian Handel, Hamish E. G. Mcwilliam, Jane E. Hodgkinson, Alasdair J. Nisbet, Vitaliy O. Kharchenko, Stewart T. G. Burgess, Jacqueline B. Matthews
Review
Parasitology
Stig M. Thamsborg, Jennifer Ketzis, Yoichiro Horii, Jacqueline B. Matthews
Article
Veterinary Sciences
Stephanie Easton, David J. Bartley, Emily Hotchkiss, Jane E. Hodgkinson, Gina L. Pinchbeck, Jacqueline B. Matthews
PREVENTIVE VETERINARY MEDICINE
(2016)
Article
Veterinary Sciences
Stephanie Easton, Gina L. Pinchbeck, David J. Bartley, Emily Hotchkiss, Jane E. Hodgkinson, Jacqueline B. Matthews
PREVENTIVE VETERINARY MEDICINE
(2016)
Article
Parasitology
Thomas Tzelos, Jacqueline B. Matthews, Amy H. Buck, Fabio Simbari, David Frew, Neil F. Inglis, Kevin McLean, Alasdair J. Nisbet, C. Bruce A. Whitelaw, David P. Knox, Tom N. McNeilly
VETERINARY PARASITOLOGY
(2016)
Article
Parasitology
L. E. Peachey, G. L. Pinchbeck, J. B. Matthews, F. A. Burden, J. M. Behnke, J. E. Hodgkinson
VETERINARY PARASITOLOGY
(2016)
Article
Parasitology
Alasdair J. Nisbet, Tom N. McNeilly, Andrew W. Greer, Yvonne Bartley, E. Margaret Oliver, Stephen Smith, Javier Palarea-Albaladejo, Jacqueline B. Matthews
VETERINARY PARASITOLOGY
(2016)
Article
Veterinary Sciences
C. H. Stratford, H. E. Lester, E. R. Morgan, K. J. Pickles, V. Relf, B. C. McGorum, J. B. Matthews
EQUINE VETERINARY JOURNAL
(2014)
Article
Parasitology
T. Tzelos, J. B. Matthews, B. Whitelaw, D. P. Knox
JOURNAL OF HELMINTHOLOGY
(2015)