T-cell therapy for viral infections

Donor-derived CMV-specific T cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation

(2013) E. Blyth et al.   BLOOD

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

(2013) A. M. Leen et al.   BLOOD

Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation

(2012) U. Gerdemann et al.   BLOOD

Rapid Salvage Treatment With Virus-Specific T Cells for Therapy-Resistant Disease

(2012) M. Uhlin et al.   CLINICAL INFECTIOUS DISEASES

Clinical-grade varicella zoster virus-specific T cells produced for adoptive immunotherapy in hemopoietic stem cell transplant recipients

(2012) Emily Blyth et al.   CYTOTHERAPY

The role of virus-specific adoptive T-cell therapy in hematopoietic transplantation

(2012) Rob S. Sellar et al.   CYTOTHERAPY

Adoptive Transfer of Epstein-Barr Virus (EBV) Nuclear Antigen 1–Specific T Cells As Treatment for EBV Reactivation and Lymphoproliferative Disorders After Allogeneic Stem-Cell Transplantation

(2012) Vanya Icheva et al.   JOURNAL OF CLINICAL ONCOLOGY

Rapidly Generated Multivirus-specific Cytotoxic T Lymphocytes for the Prophylaxis and Treatment of Viral Infections

(2012) Ulrike Gerdemann et al.   MOLECULAR THERAPY

T-cell therapy in the treatment of post-transplant lymphoproliferative disease

(2012) Catherine M. Bollard et al.   Nature Reviews Clinical Oncology

Adoptive immunotherapy with unselected or EBV-specific T cells for biopsy-proven EBV+ lymphomas after allogeneic hematopoietic cell transplantation

(2011) E. Doubrovina et al.   BLOOD

Third-party virus-specific T cells eradicate adenoviraemia but trigger bystander graft-versus-host disease

(2011) Waseem Qasim et al.   BRITISH JOURNAL OF HAEMATOLOGY

BK Virus-Specific T Cells for Use in Cellular Therapy Show Specificity to Multiple Antigens and Polyfunctional Cytokine Responses

(2011) Emily Blyth et al.   TRANSPLANTATION

Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells

(2010) A. Moosmann et al.   BLOOD

Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation

(2010) T. Feuchtinger et al.   BLOOD

Directly Selected Cytomegalovirus-Reactive Donor T Cells Confer Rapid and Safe Systemic Reconstitution of Virus-Specific Immunity Following Stem Cell Transplantation

(2010) K. S. Peggs et al.   CLINICAL INFECTIOUS DISEASES

Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirus-specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation

(2010) Anita Schmitt et al.   TRANSFUSION

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation

(2009) A. M. Leen et al.   BLOOD

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

(2009) P. J. Hanley et al.   BLOOD

Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

(2009) H. E. Heslop et al.   BLOOD

A novel haplo-identical adoptive CTL therapy as a treatment for EBV-associated lymphoma after stem cell transplantation

(2009) Michael Uhlin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Adoptive transfer of virus-specific and tumor-specific T cell immunity

(2009) Carolina Berger et al.   CURRENT OPINION IN IMMUNOLOGY