Journal
FRONTIERS IN PLANT SCIENCE
Volume 5, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2014.00598
Keywords
network visualization; pathway analysis; flux balance analysis; genome-scale metabolic reconstruction; plant metabolism
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Funding
- Ministry of Education, Culture, Sports, Science and Technology, Japan [26850024]
- Grants-in-Aid for Scientific Research [26850024] Funding Source: KAKEN
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One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms.
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