Divergent functions of the Arabidopsis mitochondrial SCO proteins: HCC1 is essential for COX activity while HCC2 is involved in the UV-B stress response

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Plants contain two SCO proteins that are differentially involved in cytochrome c oxidase function and copper and redox homeostasis

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HCC1, the Arabidopsis homologue of the yeast mitochondrial copper chaperone SCO1, is essential for embryonic development

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Human SCO2 is required for the synthesis of CO II and as a thiol-disulphide oxidoreductase for SCO1

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