Journal
FRONTIERS IN PLANT SCIENCE
Volume 3, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2012.00051
Keywords
phospholipase D; phosphatidic acid; sphingosine kina se; phytosphingosine; lipid signaling; abscisic acid
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Funding
- National Science Foundation [IOS-0818740, MCB-0922879]
- US Department of Energy [DE-SC0001295]
- Division Of Integrative Organismal Systems [0818740] Funding Source: National Science Foundation
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The activation of phospholipase D (PLD) produces phosphatidic acid (PA), whereas plant sphingosine kinase (SPHK) phosphorylates long-chain bases to generate long-chain base-1-phosphates such as phytosphingosine-1-phosphate (phyto-S1P). PA and phyto-S1P have been identified as lipid messengers. Recent studies have shown that PA interacts directly with SPHKs in Arabidopsis, and that the interaction promotes SPHK activity. However, SPHK and phyto-S1P act upstream of PLD alpha 1 and PA in the stomatal response to abscisic acid (ABA). These findings indicate that SPHK/phyto-S1P and PLD/PA are co-dependent in the amplification of lipid messengers, and that crosstalk between the sphingolipid- and phospholipid-mediated signaling pathways may play important roles in plant stress signaling.
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