Biofuel production: an odyssey from metabolic engineering to fermentation scale-up

13C-MFA delineates the photomixotrophic metabolism ofSynechocystissp. PCC 6803 under light- and carbon-sufficient conditions

(2014) Le You et al.   Biotechnology Journal

Integrating Biological Redesign: Where Synthetic Biology Came From and Where It Needs to Go

(2014) Jeffrey C. Way et al.   CELL

Narrowing the gap between the promise and reality of polyketide synthases as a synthetic biology platform

(2014) Sean Poust et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch

(2014) Yuki Soma et al.   METABOLIC ENGINEERING

Isobutanol production at elevated temperatures in thermophilic Geobacillus thermoglucosidasius

(2014) Paul P. Lin et al.   METABOLIC ENGINEERING

Elucidation of intrinsic biosynthesis yields using 13C-based metabolism analysis

(2014) Arul M Varman et al.   Microbial Cell Factories

Engineering synergy in biotechnology

(2014) Jens Nielsen et al.   Nature Chemical Biology

Envisioning the Bioconversion of Methane to Liquid Fuels

(2014) R. J. Conrado et al.   SCIENCE

Biochemical and Structural Studies of NADH-Dependent FabG Used To Increase the Bacterial Production of Fatty Acids under Anaerobic Conditions

(2013) Pouya Javidpour et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic pathway optimization using ribosome binding site variants and combinatorial gene assembly

(2013) Farnaz F. Nowroozi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Central metabolic responses to the overproduction of fatty acids inEscherichia colibased on13C-metabolic flux analysis

(2013) Lian He et al.   BIOTECHNOLOGY AND BIOENGINEERING

Transcription activator-like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing

(2013) Ning Sun et al.   BIOTECHNOLOGY AND BIOENGINEERING

Systems-wide analysis and engineering of metabolic pathway fluxes in bio-succinate producingBasfia succiniciproducens

(2013) Judith Becker et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrating multiple ‘omics’ analyses identifies serological protein biomarkers for preeclampsia

(2013) Linda Y Liu et al.   BMC Medicine

Transcriptional regulation is insufficient to explain substrate-induced flux changes in Bacillus subtilis

(2013) V. Chubukov et al.   Molecular Systems Biology

Synthetic non-oxidative glycolysis enables complete carbon conservation

(2013) Igor W. Bogorad et al.   NATURE

Microbial production of short-chain alkanes

(2013) Yong Jun Choi et al.   NATURE

Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

(2013) José L Avalos et al.   NATURE BIOTECHNOLOGY

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

(2013) Wenyan Jiang et al.   NATURE BIOTECHNOLOGY

Microbial life under extreme energy limitation

(2013) Tori M. Hoehler et al.   NATURE REVIEWS MICROBIOLOGY

Metabolic flux analysis using13C peptide label measurements

(2013) Dominic E. Mandy et al.   PLANT JOURNAL

Cyanobacterial conversion of carbon dioxide to 2,3-butanediol

(2013) John W. K. Oliver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Synthetic Biological Parts and Microbioreactors to Explore the Protein Expression Characteristics of Escherichia coli

(2013) Thomas E. Gorochowski et al.   ACS Synthetic Biology

Metabolic responses to recombinant bioprocesses in Escherichia coli

(2012) Sónia Carneiro et al.   JOURNAL OF BIOTECHNOLOGY

Metabolic engineering of Escherichia coli for the production of 1-propanol

(2012) Yong Jun Choi et al.   METABOLIC ENGINEERING

Increased lysine production by flux coupling of the tricarboxylic acid cycle and the lysine biosynthetic pathway—Metabolic engineering of the availability of succinyl-CoA in Corynebacterium glutamicum

(2012) Stefanie Kind et al.   METABOLIC ENGINEERING

Microbial engineering for the production of advanced biofuels

(2012) Pamela P. Peralta-Yahya et al.   NATURE

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

ATP drives direct photosynthetic production of 1-butanol in cyanobacteria

(2012) E. I. Lan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Science-based bioprocess design for filamentous fungi

(2012) Andreas E. Posch et al.   TRENDS IN BIOTECHNOLOGY

Genetic Circuit Performance under Conditions Relevant for Industrial Bioreactors

(2012) Felix Moser et al.   ACS Synthetic Biology

Comparative multi-omics systems analysis of Escherichia coli strains B and K-12

(2012) Sung Yoon et al.   GENOME BIOLOGY

Subpopulation-Specific Metabolic Pathway Usage in Mixed Cultures as Revealed by Reporter Protein-Based13C Analysis

(2011) Martin Rühl et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal

(2011) Antonino Baez et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Targeted proteomics for metabolic pathway optimization: Application to terpene production

(2011) Alyssa M. Redding-Johanson et al.   METABOLIC ENGINEERING

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

(2010) S. Topp et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Evaluating Factors That Influence Microbial Synthesis Yields by Linear Regression with Numerical and Ordinal Variables

(2010) Peter F. Colletti et al.   BIOTECHNOLOGY AND BIOENGINEERING

Engineering Static and Dynamic Control of Synthetic Pathways

(2010) William J. Holtz et al.   CELL

Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

(2010) Shota Atsumi et al.   Molecular Systems Biology

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

(2010) Eric J. Steen et al.   NATURE

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes

(2009) Shota Atsumi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dynamic flux responses in riboflavin overproducingBacillus subtilisto increasing glucose limitation in fed-batch culture

(2009) Martin Rühl et al.   BIOTECHNOLOGY AND BIOENGINEERING

New microbial fuels: a biotech perspective

(2009) Mathew A Rude et al.   CURRENT OPINION IN MICROBIOLOGY

A sweet out-of-the-box solution to the hydrogen economy: is the sugar-powered car science fiction?

(2009) Y.-H. Percival Zhang   Energy & Environmental Science

The RNA-induced Silencing Complex: A Versatile Gene-silencing Machine

(2009) Ashley J. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism

(2009) Pia Lindberg et al.   METABOLIC ENGINEERING

Application of dynamic flux balance analysis to an industrial Escherichia coli fermentation

(2009) Adam L. Meadows et al.   METABOLIC ENGINEERING

Integrating multiple 'omics' analysis for microbial biology: application and methodologies

(2009) W. Zhang et al.   MICROBIOLOGY-SGM

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Isotopomer Distributions in Amino Acids from a Highly Expressed Protein as a Proxy for Those from Total Protein

(2008) Afshan S. Shaikh et al.   ANALYTICAL CHEMISTRY

Identification of cellular objective for elucidating the physiological state of plasmid-bearingEscherichia coliusing genome-scalein silicoanalysis

(2008) Dave Siak-Wei Ow et al.   BIOTECHNOLOGY PROGRESS

Advances in analysis of microbial metabolic fluxes via13C isotopic labeling

(2008) Yinjie J. Tang et al.   MASS SPECTROMETRY REVIEWS

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

(2008) Shota Atsumi et al.   NATURE

Design of simple synthetic RNA thermometers for temperature-controlled gene expression in Escherichia coli

(2008) J. Neupert et al.   NUCLEIC ACIDS RESEARCH

Application of systems biology for bioprocess development

(2008) Jin Hwan Park et al.   TRENDS IN BIOTECHNOLOGY