Playing catch-up with Escherichia coli: using yeast to increase success rates in recombinant protein production experiments

Understanding the yeast host cell response to recombinant membrane protein production

(2015) Zharain Bawa et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Effects of temperature shifts and oscillations on recombinant protein production expressed in Escherichia coli

(2013) Mohammadhadi Jazini et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Quantitative comparison of dynamic physiological feeding profiles for recombinant protein production with Pichia pastoris

(2013) Oliver Spadiut et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

InPichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response

(2013) Corinna Rebnegger et al.   Biotechnology Journal

Stabilizing membrane proteins through protein engineering

(2013) Daniel J Scott et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent advances in mammalian protein production

(2013) Ashok D. Bandaranayake et al.   FEBS LETTERS

Enhanced membrane protein expression by engineering increased intracellular membrane production

(2013) Mouna Guerfal et al.   Microbial Cell Factories

Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris

(2013) Roland Prielhofer et al.   Microbial Cell Factories

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy

(2013) Mark Halliday et al.   NEUROPHARMACOLOGY

Recent advances in recombinant protein production

(2013) Renate Kunert et al.   Bioengineered

Further advances in the production of membrane proteins inPichia pastoris

(2013) Kristina Hedfalk   Bioengineered

Directed evolution of proteins for increased stability and expression using yeast display

(2012) Michael W. Traxlmayr et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Pharmaceutical protein production by yeast: towards production of human blood proteins by microbial fermentation

(2012) José L Martínez et al.   CURRENT OPINION IN BIOTECHNOLOGY

Systems metabolic engineering, industrial biotechnology and microbial cell factories

(2012) Sang-Yup Lee et al.   Microbial Cell Factories

An engineered eukaryotic protein glycosylation pathway in Escherichia coli

(2012) Juan D Valderrama-Rincon et al.   Nature Chemical Biology

Mammalian cell protein expression for biopharmaceutical production

(2011) Jianwei Zhu   BIOTECHNOLOGY ADVANCES

Mapping the yeast host cell response to recombinant membrane protein production: Relieving the biological bottlenecks

(2011) Mark P. Ashe et al.   Biotechnology Journal

Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris

(2011) Kristina Nordén et al.   BMC BIOTECHNOLOGY

GPCR production in a novel yeast strain that makes cholesterol-like sterols

(2011) Susan M. Kitson et al.   METHODS

A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris

(2011) Christian Dietzsch et al.   Microbial Cell Factories

Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris

(2011) Kristin Baumann et al.   Microbial Cell Factories

Improving recombinant eukaryotic membrane protein yields inPichia pastoris: The importance of codon optimization and clone selection

(2011) Fredrik Öberg et al.   MOLECULAR MEMBRANE BIOLOGY

Overcoming barriers to membrane protein structure determination

(2011) Roslyn M Bill et al.   NATURE BIOTECHNOLOGY

Engineering of glycosylation in yeast and other fungi: current state and perspectives

(2010) Karen De Pourcq et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of recombinant proteins and metabolites in yeasts

(2010) Danilo Porro et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Towards universal systems for recombinant gene expression

(2010) Hans Sørensen   Microbial Cell Factories

Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production

(2009) Nicklas Bonander et al.   Expert Review of Proteomics

Microbial factories for recombinant pharmaceuticals

(2009) Neus Ferrer-Miralles et al.   Microbial Cell Factories

Developing a scalable model of recombinant protein yield from Pichia pastoris: the influence of culture conditions, biomass and induction regime

(2009) William J Holmes et al.   Microbial Cell Factories

Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield

(2009) Nicklas Bonander et al.   Microbial Cell Factories

Genome sequence of the recombinant protein production host Pichia pastoris

(2009) Kristof De Schutter et al.   NATURE BIOTECHNOLOGY

Sales of biologics to show robust growth through to 2013

(2009) Michael Goodman   NATURE REVIEWS DRUG DISCOVERY

GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae

(2008) David Drew et al.   Nature Protocols