Uncovering the components of the Francisella tularensis virulence stealth strategy

Francisella tularensis Schu S4 Lipopolysaccharide Core Sugar and O-Antigen Mutants Are Attenuated in a Mouse Model of Tularemia

(2014) Jed A. Rasmussen et al.   INFECTION AND IMMUNITY

Evasion of Complement-Mediated Lysis and Complement C3 Deposition Are Regulated by Francisella tularensis Lipopolysaccharide O Antigen

(2014) C. D. Clay et al.   JOURNAL OF IMMUNOLOGY

Asparagine assimilation is critical for intracellular replication and dissemination ofFrancisella

(2013) Gael Gesbert et al.   CELLULAR MICROBIOLOGY

Differential Role for Interleukin-6 during Francisella tularensis Infection with Virulent and Vaccine Strains

(2013) Thomas R. Laws et al.   INFECTION AND IMMUNITY

Differing Effects of Interleukin-10 on Cutaneous and Pulmonary Francisella tularensis Live Vaccine Strain Infection

(2013) Dennis W. Metzger et al.   INFECTION AND IMMUNITY

The Francisella tularensis migR,trmE, andcphAGenes Contribute to F. tularensis Pathogenicity Island Gene Regulation and Intracellular Growth by Modulation of the Stress Alarmone ppGpp

(2013) Matthew Faron et al.   INFECTION AND IMMUNITY

B1a Cells Enhance Susceptibility to Infection with Virulent Francisella tularensis via Modulation of NK/NKT Cell Responses

(2013) D. D. Crane et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Francisella tularensis Intracellular Pathogenesis

(2013) J. Celli et al.   Cold Spring Harbor Perspectives in Medicine

Post-Exposure Therapeutic Efficacy of COX-2 Inhibition against Burkholderia pseudomallei

(2013) Saja Asakrah et al.   PLoS Neglected Tropical Diseases

Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

(2013) Fatma Berri et al.   PLoS Pathogens

Cytosolic clearance of replication-deficient mutants revealsFrancisella tularensisinteractions with the autophagic pathway

(2012) Audrey Chong et al.   Autophagy

Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling

(2012) Z. Zaslona et al.   BLOOD

Members of the Francisella tularensis Phagosomal Transporter Subfamily of Major Facilitator Superfamily Transporters Are Critical for Pathogenesis

(2012) Mark E. Marohn et al.   INFECTION AND IMMUNITY

Interleukin-6 Is Essential for Primary Resistance to Francisella tularensis Live Vaccine Strain Infection

(2012) Sherry L. Kurtz et al.   INFECTION AND IMMUNITY

Role of Francisella Lipid A Phosphate Modification in Virulence and Long-Term Protective Immune Responses

(2012) Duangjit Kanistanon et al.   INFECTION AND IMMUNITY

Natural IgM Mediates Complement-Dependent Uptake of Francisella tularensis by Human Neutrophils via Complement Receptors 1 and 3 in Nonimmune Serum

(2012) J. T. Schwartz et al.   JOURNAL OF IMMUNOLOGY

Subversion of Host Recognition and Defense Systems by Francisella spp.

(2012) C. L. Jones et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Characterization of Protein Glycosylation inFrancisella tularensissubsp.holarctica

(2012) Lucie Balonova et al.   MOLECULAR & CELLULAR PROTEOMICS

Signatures of T Cells as Correlates of Immunity to Francisella tularensis

(2012) Kjell Eneslätt et al.   PLoS One

Generation of a Convalescent Model of Virulent Francisella tularensis Infection for Assessment of Host Requirements for Survival of Tularemia

(2012) Deborah D. Crane et al.   PLoS One

Francisella tularensis Elicits IL-10 via a PGE2-Inducible Factor, to Drive Macrophage MARCH1 Expression and Class II Down-Regulation

(2012) Danielle Hunt et al.   PLoS One

Low Dose Vaccination with Attenuated Francisella tularensis Strain SchuS4 Mutants Protects against Tularemia Independent of the Route of Vaccination

(2012) Dedeke Rockx-Brouwer et al.   PLoS One

A Typical Preparation ofFrancisella tularensisO-Antigen Yields a Mixture of Three Types of Saccharides

(2011) Qi Wang et al.   BIOCHEMISTRY

Tularemia vaccines: recent developments and remaining hurdles

(2011) J Wayne Conlan   Future Microbiology

Phagocytic Receptors Dictate Phagosomal Escape and Intracellular Proliferation of Francisella tularensis

(2011) Henriette Geier et al.   INFECTION AND IMMUNITY

O-Linked Glycosylation of the PilA Pilin Protein of Francisella tularensis: Identification of the Endogenous Protein-Targeting Oligosaccharyltransferase and Characterization of the Native Oligosaccharide

(2011) W. Egge-Jacobsen et al.   JOURNAL OF BACTERIOLOGY

Features of sepsis caused by pulmonary infection with Francisella tularensis Type A strain

(2011) Jyotika Sharma et al.   MICROBIAL PATHOGENESIS

Isolation and Mutagenesis of a Capsule-Like Complex (CLC) from Francisella tularensis, and Contribution of the CLC to F. tularensis Virulence in Mice

(2011) Aloka B. Bandara et al.   PLoS One

Host-Adaptation of Francisella tularensis Alters the Bacterium's Surface-Carbohydrates to Hinder Effectors of Innate and Adaptive Immunity

(2011) Tiffany M. Zarrella et al.   PLoS One

Immunity to Francisella

(2011) Siobhán C. Cowley et al.   Frontiers in Microbiology

The Subversion of the Immune System by Francisella Tularensis

(2011) Catharine M. Bosio   Frontiers in Microbiology

Francisella tularensis  pyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo

(2010) J. Horzempa et al.   INFECTION AND IMMUNITY

Francisella tularensisSchu S4 O-Antigen and Capsule Biosynthesis Gene Mutants Induce Early Cell Death in Human Macrophages

(2010) Stephen R. Lindemann et al.   INFECTION AND IMMUNITY

Multimethodological Approach to Identification of Glycoproteins from the Proteome ofFrancisella tularensis, an Intracellular Microorganism

(2010) Lucie Balonova et al.   JOURNAL OF PROTEOME RESEARCH

Identification, Characterization and Immunogenicity of an O-Antigen Capsular Polysaccharide of Francisella tularensis

(2010) Michael A. Apicella et al.   PLoS One

Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype

(2009) Jessica G. Moreland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intracellular biology and virulence determinants ofFrancisella tularensisrevealed by transcriptional profiling inside macrophages

(2009) Tara D. Wehrly et al.   CELLULAR MICROBIOLOGY

Oral Live Vaccine Strain-Induced Protective Immunity against Pulmonary Francisella tularensis Challenge Is Mediated by CD4+ T Cells and Antibodies, Including Immunoglobulin A

(2009) H. J. Ray et al.   Clinical and Vaccine Immunology

Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome

(2009) D. L. Clemens et al.   INFECTION AND IMMUNITY

Francisella tularensis Induces Ubiquitin-Dependent Major Histocompatibility Complex Class II Degradation in Activated Macrophages

(2009) J. E. Wilson et al.   INFECTION AND IMMUNITY

Identification of migR, a Regulatory Element of the Francisella tularensis Live Vaccine Strain iglABCD Virulence Operon Required for Normal Replication and Trafficking in Macrophages

(2009) B. W. Buchan et al.   INFECTION AND IMMUNITY

Francisella tularensis Genes Required for Inhibition of the Neutrophil Respiratory Burst and Intramacrophage Growth Identified by Random Transposon Mutagenesis of Strain LVS

(2009) G. S. Schulert et al.   INFECTION AND IMMUNITY

A Novel Role for Plasmin-Mediated Degradation of Opsonizing Antibody in the Evasion of Host Immunity by Virulent, but Not Attenuated, Francisella tularensis

(2009) D. D. Crane et al.   JOURNAL OF IMMUNOLOGY

Proteome Analysis of an AttenuatedFrancisella tularensis dsbAMutant: Identification of Potential DsbA Substrate Proteins

(2009) Adela Straskova et al.   JOURNAL OF PROTEOME RESEARCH

Restricted cytosolic growth of Francisella tularensis subsp. tularensis by IFN-  activation of macrophages

(2009) J. A. Edwards et al.   MICROBIOLOGY-SGM

Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

(2009) L. E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential ability of novel attenuated targeted deletion mutants of Francisella tularensis subspecies tularensis strain SCHU S4 to protect mice against aerosol challenge with virulent bacteria: Effects of host background and route of immunization

(2009) J. Wayne Conlan et al.   VACCINE

Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis

(2009) Khaled Alkhuder et al.   PLoS Pathogens

Small Molecule Control of Virulence Gene Expression in Francisella tularensis

(2009) James C. Charity et al.   PLoS Pathogens

Humoral and cell-mediated immunity to the intracellular pathogenFrancisella tularensis

(2008) Girish S. Kirimanjeswara et al.   IMMUNOLOGICAL REVIEWS

Identification of fevR, a Novel Regulator of Virulence Gene Expression in Francisella novicida

(2008) A. Brotcke et al.   INFECTION AND IMMUNITY

RipA, a Cytoplasmic Membrane Protein Conserved among Francisella Species, Is Required for Intracellular Survival

(2008) J. R. Fuller et al.   INFECTION AND IMMUNITY

MglA and Igl Proteins Contribute to the Modulation of Francisella tularensis Live Vaccine Strain-Containing Phagosomes in Murine Macrophages

(2008) L. Bonquist et al.   INFECTION AND IMMUNITY

The Early Phagosomal Stage of Francisella tularensis Determines Optimal Phagosomal Escape and Francisella Pathogenicity Island Protein Expression

(2008) A. Chong et al.   INFECTION AND IMMUNITY

The Francisella Pathogenicity Island Protein PdpD Is Required for Full Virulence and Associates with Homologues of the Type VI Secretion System

(2008) J. S. Ludu et al.   JOURNAL OF BACTERIOLOGY

A Francisella tularensis Schu S4 Purine Auxotroph Is Highly Attenuated in Mice but Offers Limited Protection against Homologous Intranasal Challenge

(2008) Roger D. Pechous et al.   PLoS One