Article
Multidisciplinary Sciences
Kyung Koh, Giovanni Oppizzi, Glenn Kehs, Li-Qun Zhang
Summary: Using an exoskeleton robot, researchers found that stroke survivors have impaired abilities in coordinating multiple joints of the arm, especially during reaching tasks. These findings contribute to a better understanding of motor impairment and suggest the potential for impairment-specific treatments to improve upper extremity synergies.
SCIENTIFIC REPORTS
(2023)
Review
Clinical Neurology
Silke Wolf, Christian Gerloff, Winifried Backhaus
Summary: This study highlights the challenges in assessing upper limb motor recovery after stroke and the importance of mechanism evaluation and data collection to facilitate standardization and comparison of assessment methods in the future.
FRONTIERS IN NEUROLOGY
(2021)
Article
Engineering, Biomedical
Donovan B. Smith, Stephen H. Scott, Jennifer A. Semrau, Sean P. Dukelow
Summary: This study assessed ipsilesional arm motor impairments using a robot-based assessment over the first 6 months post-stroke. The robot-based assessment revealed a higher incidence of ipsilesional arm impairments than clinical measures. The severity of ipsilesional arm impairments was moderately correlated with contralesional arm impairment severity, but not with the hemisphere of lesion.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Clinical Neurology
Kuem Ju Lee, Gyulee Park, Joon-Ho Shin
Summary: Robotic rehabilitation after stroke has shown positive effects on motor and cognitive functions, with more consistent improvements in motor function. However, there were no significant changes in the dual-task effects of motor and cognitive performance after robotic rehabilitation.
FRONTIERS IN NEUROLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Ze-Jian Chen, Chang He, Nan Xia, Ming-Hui Gu, Yang-An Li, Cai-Hua Xiong, Jiang Xu, Xiao-Lin Huang
Summary: The study revealed that kinematic components during the finger-to-nose test are associated with upper extremity motor function in subacute stroke survivors. Three principal components, accounting for 91.3% variance, include metrics such as mean velocity, peak velocity, number of movement units, and normalized integrated jerk.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Health Care Sciences & Services
Jungsoo Lee, Won Hyuk Chang, Yun-Hee Kim
Summary: Understanding the interaction between the corticospinal tract (CST) and corticocerebellar tract (CCT) can enhance the individualized rehabilitative strategies and predictive accuracy for stroke patients. The study found that the CCT was significantly associated with high CST FA, indicating a conditional role of CCT depending on CST status in upper extremity recovery after stroke.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Engineering, Biomedical
Andrea M. Kuczynski, Adam Kirton, Jennifer A. Semrau, Sean P. Dukelow
Summary: This study explored the relationship between position sense and reaching ability in children with hemiparetic upper limbs following perinatal stroke using robotic technology and clinical measures. The findings suggest that deficits in sensory and motor function measured by robots are only moderately correlated with clinical tests, indicating relative independence between position sense and reaching with the contralesional limb in children with stroke.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Camila L. A. Gomes, Roberta O. Cacho, Viviane T. B. Nobrega, Fabio Galvao, Denise S. de Araujo, Ana Loyse de S. Medeiros, Emanoelle C. Silva, Rodrigo L. Barreto, Enio W. A. Cacho
Summary: The study examined the effects of internal and external attentional focus on upper limb motor performance in post-stroke individuals. Internal focus showed significant results in movement time and velocity.
Article
Behavioral Sciences
Ji-Ae Yu, JuHyung Park
Summary: The effects of First-Person Perspective Action Observation training and Third-Person Perspective Action Observation training on upper extremity function and activities of daily living in stroke patients were investigated. Both trainings significantly improved the upper extremity function and daily activities, with First-Person Perspective Action Observation training being more effective.
BRAIN AND BEHAVIOR
(2022)
Article
Chemistry, Analytical
Pawel Sip, Marta Kozlowska, Dariusz Czysz, Przemyslaw Daroszewski, Przemyslaw Lisinski
Summary: Stroke is a major cause of disability, including loss of hand manipulative skills. Virtual reality (VR) is increasingly being used as a physiotherapeutic method. This study compared the effectiveness of VR application Virtual Mirror Hand 1.0 to classical mirror therapy in restoring post-stroke hand function. The results showed that VR application had subjective advantages in ameliorating pain and sensory impressions.
Article
Neurosciences
Katherine Pham, Manuel Portilla-Jimenez, Jinsook Roh
Summary: This study investigated the generalizability of muscle synergies in isometric force generation and kinematic reaching tasks in the upper extremity. Thirteen arm, shoulder, and back muscles were recorded while participants performed these tasks. Non-negative matrix factorization was used to identify the muscle synergies. It was found that the number and composition of muscle synergies were consistent across different arm positions and tasks.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Rehabilitation
Lina Daghsen, Lisa Fleury, Justine Bouvier, Chiara Zavanone, Sophie Dupont, Friedhelm Christoph Hummel, Charlotte Rosso
Summary: The objective of this study was to create a shortened version of the Action Research Arm Test scale, investigate its psychometric properties compared to the original scale, and externally validate it within an independent cohort. The results showed that the Mini-ARAT is a time-effective tool that accurately captures the dynamics of motor deficits and provides important information for clinical and research purposes.
CLINICAL REHABILITATION
(2022)
Article
Clinical Neurology
Leticia Hayes, Myriam Taga, Charalambos C. Charalambous, Sharmila Raju, Jing Lin, Heidi M. Schambra
Summary: This study found that the distribution of transcallosal inhibition acting on proximal and distal upper extremity muscles is altered in chronic stroke patients.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Engineering, Biomedical
Majid Abedi, Saeed Behzadipour
Summary: Background: Although kinematic assessment has potentials for better evaluation of the movement quality, they are not widely used in clinics. Besides the equipment cost, the contradictory results of their clinimetric analysis are presumed as a major reason. This raises concerns about whether the current kinematic indices are intrin-sically sound and truly reflect the quality of the subjects' movement.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Multidisciplinary Sciences
Darrin O. Wijeyaratnam, Thomas Edwards, Lara A. Pilutti, Erin K. Cressman
Summary: The ability to accurately complete goal-directed actions is impaired in people with multiple sclerosis (PwMS), which is attributed to deficits in the planning and/or control of their movements. This suggests that compensatory mechanisms may be employed by PwMS to overcome impairments in movement planning.
Article
Rehabilitation
Marina Portugal Makhoul, Elen Beatriz Pinto, Natalia Araujo Mazzini, Carolee Winstein, Camila Torriani-Pasin
TOPICS IN STROKE REHABILITATION
(2020)
Article
Clinical Neurology
Rini Varghese, Carolee J. Winstein
FRONTIERS IN NEUROLOGY
(2020)
Article
Rehabilitation
Clarisa Martinez, Helen Bacon, Veronica Rowe, David Russak, Erin Fitzgerald, Michelle Woodbury, Steven L. Wolf, Carolee Winstein
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2020)
Review
Neurosciences
Sook-Lei Liew, Artemis Zavaliangos-Petropulu, Neda Jahanshad, Catherine E. Lang, Kathryn S. Hayward, Keith R. Lohse, Julia M. Juliano, Francesca Assogna, Lee A. Baugh, Anup K. Bhattacharya, Bavrina Bigjahan, Michael R. Borich, Lara A. Boyd, Amy Brodtmann, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Adriana B. Conforto, R. Cameron Craddock, Michael A. Dimyan, Adrienne N. Dula, Elsa Ermer, Mark R. Etherton, Kelene A. Fercho, Chris M. Gregory, Shahram Hadidchi, Jess A. Holguin, Darryl H. Hwang, Simon Jung, Steven A. Kautz, Mohamed Salah Khlif, Nima Khoshab, Bokkyu Kim, Hosung Kim, Amy Kuceyeski, Martin Lotze, Bradley J. MacIntosh, John L. Margetis, Feroze B. Mohamed, Fabrizio Piras, Ander Ramos-Murguialday, Genevieve Richard, Pamela Roberts, Andrew D. Robertson, Jane M. Rondina, Natalia S. Rost, Nerses Sanossian, Nicolas Schweighofer, Na Jin Seo, Mark S. Shiroishi, Surjo R. Soekadar, Gianfranco Spalletta, Cathy M. Stinear, Anisha Suri, Wai Kwong W. Tang, Gregory T. Thielman, Daniela Vecchio, Arno Villringer, Nick S. Ward, Emilio Werden, Lars T. Westlye, Carolee Winstein, George F. Wittenberg, Kristin A. Wong, Chunshui Yu, Steven C. Cramer, Paul M. Thompson
Summary: The ENIGMA Stroke Recovery working group aims to understand the relationship between brain and behavior using meta- and mega-analytic approaches. They have developed neuroinformatics protocols and methods to manage large-scale data from over 2,100 stroke patients. The challenges and recommendations for data harmonization in stroke research are discussed.
HUMAN BRAIN MAPPING
(2022)
Article
Biophysics
Hai-Jung Steffi Shih, James Gordon, Kornelia Kulig
Summary: This study examined trunk control in response to different step widths using a novel feedback system. The results showed that trunk kinematics in all three planes were affected by changes in step width, with wider widths mainly impacting the transverse plane and narrower widths mainly impacting the frontal plane. Additionally, activation of the longissimus muscle increased as step widths became narrower.
JOURNAL OF BIOMECHANICS
(2021)
Article
Clinical Neurology
Reed Handlery, Elizabeth W. Regan, Jill C. Stewart, Christine Pellegrini, Courtney Monroe, Garrett Hainline, Kaci Handlery, Stacy L. Fritz
Summary: This study found that daily steps and balance at 2 months poststroke were the strongest predictors of future daily steps. Improving daily physical activity and targeting balance early after stroke may be necessary to increase physical activity at 1-year poststroke.
Article
Biochemical Research Methods
Allison F. Lewis, Jill C. Stewart
Summary: This study compared CST integrity measures extracted from standard versus native space in individuals with chronic stroke, finding significant differences between the two extraction methods. The influence of extraction space on diffusion-based microstructural integrity values (FA and MD) of the CST is important when considering methods for aggregating data across studies, but the relationship between CST integrity and motor impairment appears to be robust to extraction space.
JOURNAL OF NEUROSCIENCE METHODS
(2021)
Article
Orthopedics
Ndidiamaka D. Matthews, K. Michael Rowley, Stacey C. Dusing, Libby Krause, Noriko Yamaguchi, James Gordon
Article
Clinical Neurology
Denise M. Peters, Julius Fridriksson, Jessica D. Richardson, Jill C. Stewart, Chris Rorden, Leonardo Bonilha, Addie Middleton, Stacy L. Fritz
Summary: The microstructural integrity of the ipsilesional corticospinal tract is associated with upper and lower limb motor function after stroke, while the integrity of the ipsilesional red nucleus is also related to motor performance.
BEHAVIOURAL NEUROLOGY
(2021)
Article
Neurosciences
Andrew Hooyman, James Gordon, Carolee Winstein
Summary: This study explored the differences in motor learning capability among individuals using a rule-based visuomotor task, identifying distinct subgroups based on task performance and success levels. It found that high performers were able to acquire task components in parallel, highlighting differing strategies associated with expertise in motor learning.
HUMAN MOVEMENT SCIENCE
(2021)
Article
Orthopedics
Kristan A. Leech, Ryan T. Roemmich, James Gordon, Darcy S. Reisman, Kendra M. Cherry-Allen
Summary: The volume of human motor learning research has grown significantly over the past 3 decades, leading to an evolved understanding of motor learning mechanisms. It is now known that there are multiple mechanisms through which motor learning occurs, each with its own distinctive features and governed by distinct neural substrates. This expanded understanding has important implications for physical therapy, as it can facilitate the development of more precise treatment approaches to improve human movement.
Article
Neurosciences
Jill Campbell Stewart, Jessica F. Baird, Allison F. Lewis, Stacy L. Fritz, Julius Fridriksson
Summary: Practice after stroke can improve action selection performance and reduce brain activation. Systematic changes in practice conditions may allow targeted treatment of specific components of the motor network during stroke rehabilitation.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Letter
Orthopedics
James Gordon, Julie K. Tilson
Article
Neurosciences
Elizabeth Regan, Julius Fridriksson, Sydney Y. Schaefer, Chris Rorden, Leonardo Bonilha, Jennapher Lingo VanGilder, Jill Campbell Stewart
Summary: The study found that while baseline motor performance in stroke patients correlated with the integrity of the CST, within-session practice effects were correlated with the degree of lesion to the superior longitudinal fasciculus, suggesting different white matter tracts are associated with baseline performance and practice effects.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Rehabilitation
Jill Campbell Stewart, Ashley Saba, Jessica F. Baird, Melissa B. Kolar, Michael O'Donnell, Sydney Y. Schaefer
Summary: This study examined the effect of standing on upper extremity function measurement, revealing that completion time increased in standing compared to sitting, especially for tasks like Checker stacking.
OTJR-OCCUPATION PARTICIPATION AND HEALTH
(2021)