Article
Clinical Neurology
Komal Bharti, Giulia Conte, Silvia Tommasin, Costanza Gianni, Antonio Suppa, Giovanni Mirabella, Francesco Cardona, Patrizia Pantano
Summary: This study compared early structural white matter changes in drug-naive children with Tourette syndrome (TS) and early-onset obsessive-compulsive disorder (OCD) using diffusion tensor imaging (DTI). The results showed different alterations in white matter microstructure in TS with or without OCD compared to OCD alone, suggesting that TS+OCD is a subtype of TS while OCD has independent pathophysiological mechanisms affecting white matter development.
FRONTIERS IN NEUROLOGY
(2022)
Review
Neurosciences
Ekaterina Lunkova, Guido Guberman, Alain Ptito, Rajeet Singh Saluja
Summary: This review discusses various imaging methods for concussion, including fMRI, SWI, dMRI, and ASL, highlighting their benefits and drawbacks. A multimodal approach is recommended for a comprehensive understanding of mild traumatic brain injury mechanisms.
HUMAN BRAIN MAPPING
(2021)
Article
Engineering, Biomedical
Shuhei Shibukawa, Tetsu Niwa, Tosiaki Miyati, Tetsuo Ogino, Daisuke Yoshimaru, Kagayaki Kuroda
Summary: In this study, the application of second-order motion compensation diffusion tensor imaging (2nd-MC DTI) with fractional anisotropy (FA) processing was found to reduce the impact of pulsation on CSF temperature measurements, improving the accuracy of intracranial CSF temperature determination.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Medicine, General & Internal
Ningbo Fei, Guangsheng Li, Xuxiang Wang, Junpeng Li, Xiaosong Hu, Yong Hu
Summary: In this study, an automatic segmentation method based on ROI was proposed for the diagnosis of Cervical Spondylotic Myelopathy (CSM). The UNet model was trained with the proposed heatmap distance loss to accurately segment the spinal cord images. The ROI-based mean FA values showed strong correlation with the values based on manual drawing, indicating the potential of this method to quantify the detailed status of the cervical spinal cord.
Review
Clinical Neurology
Juming Ma, Xue Yang, Fan Xu, Hongjun Li
Summary: This research evaluates the consistency and differences in the correlation between HAND and DTI measures in various studies. The results show that patients with HAND have significant changes in white matter fibers compared to healthy individuals in terms of fractional anisotropy and mean diffusivity. However, there are heterogeneities between the studies, which can be attributed to demographics, antiretroviral therapy, nadir CD4+ T cell levels, and the use of different neurocognitive function scales. DTI is an effective method for diagnosing HAND, but there are still limitations, particularly in the absence of neurocognitive function scales.
FRONTIERS IN NEUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Clara Engelhardt, Benoit Boulat, Michael Czisch, Mathias V. Schmidt
Summary: This study demonstrated that a lack of FKBP51 leads to alterations in brain architecture and connectivity in male mice through the use of in vivo structural MRI and DTI.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Geriatrics & Gerontology
Andrei A. Vakhtin, Yu Zhang, Max Wintermark, John W. Ashford, Ansgar J. Furst
Summary: The study found that distant mTBIs may accelerate normal age-related trajectories of WM degeneration, especially in middle and late adulthood. However, no interactions between prior injuries and age were detected when examining linear trajectories. Thus, life-long histories of head trauma should be assessed in all patients in their mid-to-late adulthoods, whether neurologically healthy or presenting with seemingly unrelated neuropathology.
NEUROBIOLOGY OF AGING
(2021)
Review
Pharmacology & Pharmacy
Piotr Podwalski, Krzysztof Szczygiel, Ernest Tyburski, Leszek Sagan, Blazej Misiak, Jerzy Samochowiec
Summary: DTI is an imaging technique that measures the diffusion of water molecules in tissues, helping to understand white matter integrity disorders and potentially leading to better methods of psychiatric diagnosis and treatment.
PHARMACOLOGICAL REPORTS
(2021)
Article
Clinical Neurology
Xiaojia Yuan, Xiaozhen Li, Yu Xu, Liqun Zhong, Zhanfeng Yan, Zhengguang Chen
Summary: This study used DTI to assess microstructural changes of the vestibulocochlear nerve in patients with Meniere's disease. The results showed that MD patients had decreased FA and increased ADC compared to healthy controls. Furthermore, FA was negatively correlated with DHI scores. These findings provide initial evidence for possible nerve changes in patients with MD.
FRONTIERS IN NEUROLOGY
(2022)
Article
Veterinary Sciences
Kiyotaka Arai, Takamasa Itoi, Natsuki Akashi, Masahiro Miyabe, Keisuke Sugimoto, Akira Matsuda, Noritaka Maeta, Teppei Kanda, Kenji Kutara
Summary: This study performed diffusion tensor imaging (DTI) scans on adult Beagle dogs and analyzed DTI parameters in different regions. The results showed that DTI parameters significantly decreased in the caudal direction, but were not significantly correlated with vertebral levels. These findings contribute to the development of a clinical reference for evaluating spinal cord in dogs using DTI parameters.
VETERINARY SCIENCES
(2023)
Article
Neurosciences
Patcharaporn Srisaikaew, Jordan A. Chad, Pasuk Mahakkanukrauh, Nicole D. Anderson, J. Jean Chen
Summary: This study aimed to investigate the influence of the APOE4 genotype on brain microstructure in cognitively normal older adults. The results showed that age-related effects on white-matter microstructure were independent of APOE4 status, but differed between sexes, highlighting the importance of considering sex differences in APOE research. Additionally, the DT-DOME was found to be more sensitive than conventional DTI metrics in detecting age-related and sex effects, especially in crossing white matter fiber regions, suggesting its potential use in further research on white matter microstructure across the life span in both healthy and diseased populations.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Endocrinology & Metabolism
Cong Zhou, Jie Li, Man Dong, Liangliang Ping, Hao Lin, Yuxin Wang, Shuting Wang, Shuo Gao, Ge Yu, Yuqi Cheng, Xiufeng Xu
Summary: This meta-analysis examined white matter microstructural alterations in patients with type 2 diabetes mellitus and found reductions in fractional anisotropy in the left inferior network, corpus callosum, and left olfactory cortex. Additionally, a negative correlation was observed between fractional anisotropy in the corpus callosum and BMI in the patient group.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Timothy T. Griffiths, Robert Flather, Irvin Teh, Hamied A. Haroon, David Shelley, Sven Plein, Grainne Bourke, Ryckie G. Wade
Summary: This study compared the DTI metrics of healthy adults and patients with CuTS, finding that diffusion in the ulnar nerve of CuTS patients was more isotropic.
SCIENTIFIC REPORTS
(2021)
Article
Behavioral Sciences
Justine Daoust, Joelle Schaffer, Yashar Zeighami, Alain Dagher, Isabel Garcia-Garcia, Andreanne Michaud
Summary: Research has shown that individuals with obesity tend to have lower white matter integrity, particularly in the genu of the corpus callosum, a tract linking areas involved in executive function. Further studies are needed to explore the mechanisms linking obesity with loss of white matter integrity.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yin Liu, Fengfang Li, Song'an Shang, Peng Wang, Xindao Yin, Vijaya Prakash Krishnan Muthaiah, Liyan Lu, Yu-Chen Chen
Summary: This study investigated the changes in large-scale functional connectivity (FC) and structural connectivity (SC) networks in acute mild traumatic brain injury (mTBI) and their potential relevance to cognitive impairment. Aberrant global and nodal topological properties in FC and SC were observed in mTBI patients, particularly in the frontal and temporal regions, cerebellum, and subcortical areas. These network changes were associated with attention, orientation, memory, and naming performances.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Sport Sciences
Daria M. Oller, W. E. Buckley, Wayne J. Sebastianelli, Giampietro L. Vairo
JOURNAL OF ATHLETIC TRAINING
(2015)
Article
Clinical Neurology
Kathleen L. Poston, Sophie YorkWilliams, Kai Zhang, Weidong Cai, David Everling, Fadi M. Tayim, Seoni Llanes, Vinod Menon
ANNALS OF NEUROLOGY
(2016)
Editorial Material
Sport Sciences
Wayne J. Sebastianelli
SPORTS MEDICINE AND ARTHROSCOPY REVIEW
(2016)
Article
Orthopedics
Giampietro L. Vairo, Sayers J. Miller, Paul S. Sherbondy, Wayne J. Sebastianelli, William E. Buckley
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2013)
Article
Neuroimaging
Semyon Slobounov, Michael Gay, Brian Johnson, Kai Zhang
BRAIN IMAGING AND BEHAVIOR
(2012)
Article
Neuroimaging
Brian Johnson, Kai Zhang, Mark Hallett, Semyon Slobounov
BRAIN IMAGING AND BEHAVIOR
(2015)
Article
Clinical Neurology
Semyon Slobounov, Wayne Sebastianelli, Mark Hallett
CLINICAL NEUROPHYSIOLOGY
(2012)
Article
Pediatrics
Daria M. Oller, Giampietro L. Vairo, Wayne J. Sebastianelli, William E. Buckley
CLINICAL PEDIATRICS
(2013)
Article
Critical Care Medicine
Brian Johnson, Michael Gay, Kai Zhang, Thomas Neuberger, Silvina G. Horovitz, Mark Hallett, Wayne Sebastianelli, Semyon Slobounov
JOURNAL OF NEUROTRAUMA
(2012)
Article
Critical Care Medicine
Kai Zhang, Brian Johnson, Michael Gay, Silvina G. Horovitz, Mark Hallett, Wayne Sebastianelli, Semyon Slobounov
JOURNAL OF NEUROTRAUMA
(2012)
Article
Neurosciences
Brian Johnson, Kai Zhang, Michael Gay, Silvina Horovitz, Mark Hallett, Wayne Sebastianelli, Semyon Slobounov
Article
Neurosciences
Brian Johnson, Kai Zhang, Michael Gay, Thomas Neuberger, Silvina Horovitz, Mark Hallett, Wayne Sebastianelli, Semyon Slobounov
NEUROSCIENCE LETTERS
(2012)
Article
Rehabilitation
Javier A. Osorio, Giampietro L. Vairo, Gerard D. Rozea, Philip J. Bosha, Roberta L. Millard, Douglas F. Aukerman, Wayne J. Sebastianelli
PHYSICAL THERAPY IN SPORT
(2013)