Article
Neurosciences
Susan King, Kilian Dahlem, Faisal Karmali, Konstantina M. Stankovic, D. Bradley Welling, Richard F. Lewis
Summary: The severity of symptoms associated with vestibular schwannomas (VS) is poorly correlated with standard vestibulo-ocular reflex (VOR) metrics that are based on response amplitude. Imbalance in patients with VS scales with VOR precision and time constant, but not with VOR accuracy. Dizziness is related to the presence of a static central tone imbalance but not to any VOR metrics.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Isaura Rodriguez Montesdeoca, Angel Ramos de Miguel, Juan Carlos Falcon Gonzalez, Silvia Borkoski Barreiro, Nicolas Perez Fernandez, Robby Vanspauwen, Angel Ramos-Macias
Summary: The study analyzed vestibular-evoked myogenic potentials (VEMPs) obtained from patients implanted with cochlear and vestibulo-cochlear implants, showing that electrically evoked cVEMPs can be present after cochlear and vestibular stimulation, suggesting stimulation of vestibular elements which warrants further clinical study.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Feray Gulec Uyaroglu, Roza Ucar, Ahmet Acarer, Nese Celebisoy
Summary: In this study, cervical vestibular-evoked myogenic potentials (cVEMPs) were studied in essential tremor (ET) patients to explore the interaction between the tremor network and the vestibular neural pathways. The results showed that cVEMP responses were affected in ET patients, which could be caused by dysfunctional structures or pathways responsible for ET, or an additional disorder of vestibular information processing in these patients.
NEUROLOGICAL SCIENCES
(2021)
Article
Neurosciences
Bernardo Faria Ramos, Renato Cal, Sergio Carmona, Konrad P. Weber, Francisco Zuma e Maia
Summary: The VVOR and VORS tests can be used to evaluate eye movements in patients with vestibular hypofunction, with unilateral patients exhibiting corrective eye movements towards the healthy side, while bilateral patients do not exhibit corrective eye movements.
Article
Clinical Neurology
Priyani Patel, Patricia Castro, Nehzat Koohi, Qadeer Arshad, Lucia Gargallo, Sergio Carmona, Diego Kaski
Summary: This study explores whether the vestibulo-ocular reflex (VOR) gain changes in response to a clinical headshake maneuver in patients with vestibular migraine (VM). The study found that there was no significant change in VOR gain after headshaking in any group. Patients who reported nausea when reading in the passenger seat of a car were more likely to have VM.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Tianwen Chen, Jun Huang, Yue Yu, Xuehui Tang, Chunming Zhang, Youguo Xu, Alberto Arteaga, Jerome Allison, William Mustain, Matthew C. Donald, Tracy Rappai, Michael Zhang, Wu Zhou, Hong Zhu
Summary: Sound stimuli not only activate otolith afferents but also canal afferents, demonstrating contributions of canals to vestibular evoked myogenic potentials. Neural mechanisms underlying VEMPs were further examined by studying sound responses of vestibular nucleus neurons and abducens neurons. The convergent canal and otolith inputs in VOR pathways were characterized by specific tuning curves of sound-sensitive neurons, which also resulted in defined eye movements measurable by eye tracking devices for testing vestibular function.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Cell Biology
Marta Barandela, Carmen Nunez-Gonzalez, Daichi G. Suzuki, Cecilia Jimenez-Lopez, Manuel A. Pombal, Juan Perez-Fernandez
Summary: Animals constantly adjust their gaze to stabilize their vision, with stabilizing movements appearing before goal-oriented responses during the development of the lamprey visual system. This finding provides valuable insights into the evolutionary and developmental processes of vertebrate vision.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Martin Hitier, Yan-Feng Zhang, Go Sato, Stephane Besnard, Yiwen Zheng, Paul F. Smith
Summary: This study demonstrates the importance of vestibular information for hippocampal function and spatial memory, showing that stimulation of the same vestibular sensor can activate different specific areas in the hippocampus. The results suggest bilateral input to the hippocampus, with a high level of redundancy in the representation of vestibular information.
Article
Clinical Neurology
Ning Ma, Handi Liu, Bing Liu, Li Zhang, Bei Li, Yang Yang, Wei Liu, Min Chen, Jianbo Shao, Xiao Zhang, Xin Ni, Jie Zhang
Summary: This study aimed to evaluate the effectiveness and acceptance of Vestibulo-Ocular Reflex (VOR) adaptation training in children with recurrent vertigo. The results showed that VOR adaptation training can effectively improve vertigo symptoms and is more accepted by children compared to classic Cawthorne-Cooksey training.
FRONTIERS IN NEUROLOGY
(2022)
Article
Sport Sciences
Daniel A. Brown, Felix T. Leung, Kerrie Evans, Gary Grant, Julie A. Hides
Summary: This study investigated the differences in vestibulo-ocular function between active male combat sport athletes and a healthy control group. The findings revealed a higher prevalence of oculomotor abnormalities in the combat sport athletes, but no significant differences in other aspects of vestibulo-ocular function. The combat sport athletes also had higher symptom-based outcome scores. These findings can assist clinicians in identifying combat sport athletes with underlying vestibulo-ocular dysfunction and prompting further investigation.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2022)
Article
Clinical Neurology
Jacob M. Pogson, Rachael L. Taylor, Andrew P. Bradshaw, Leigh McGarvie, Mario D'Souza, Sean Flanagan, Jonathan Kong, Nigel Biggs, Brindha Shivalingam, Simon Greenberg, Glen Croxson, G. Michael Halmagyi, Miriam S. Welgampola
Summary: The vestibulo-ocular reflex (VOR) and compensatory-saccades undergo changes after surgical unilateral vestibular deafferentation (UVD). Compensatory-saccades adapt within one week post-surgery and remain stable over one year.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Jennifer Wing Yee Lee, Fatemeh Hassannia, John Alexander Rutka
Summary: The study investigated the impact of unilateral vestibular schwannoma on VOR function, finding both ipsilesional and contralesional VOR impairment in patients, with bilateral VOR impairment correlating with tumor size. Brainstem compression was associated with reduced ipsilesional VOR gain, but not contralesional VOR gain.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Clinical Neurology
Carlo N. Rinaudo, Michael C. Schubert, Phillip D. Cremer, William V. C. Figtree, Christopher J. Todd, Americo A. Migliaccio
Summary: Incremental VOR training shows significant improvement in VOR gain, balance during gait with head rotation, and symptoms in patients with chronic peripheral vestibular hypofunction. This training method may be more effective than conventional x1 gaze-stabilizing exercises.
JOURNAL OF NEUROLOGIC PHYSICAL THERAPY
(2021)
Article
Clinical Neurology
Akiyoshi Matsugi, Tomoyuki Shiozaki, Hiroaki Tanaka
Summary: The study investigated the effects of noisy galvanic vestibular stimulation (nGVS) on the vestibulo-ocular reflex (VOR) and body sway. Results showed that nGVS at 0.2 mA inhibited the VOR, while nGVS at 0.6 mA increased body sway during upright standing. However, there may not be a significant relationship between these effects in healthy individuals.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Deniz Ugur Cengiz, Hatice Seyra Erbek, Sanem Can Colak, Buesra Kurtcu, Suemeyye Demirel Birisik, Ercan Karababa, Busra Kusman, Emre Akguen Ozdemir, Mehmet Isik, Ismail Demir
Summary: This study aimed to determine the normative values of the functional head impulse test (fHIT) in healthy young adults. The results showed differences in fHIT values between different semicircular canals and genders, providing important data for future studies.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Courtney E. Stewart, Ariane C. Kanicki, Richard A. Altschuler, W. M. King
JOURNAL OF NEUROPHYSIOLOGY
(2018)
Article
Neurosciences
C. E. Stewart, D. S. Bauer, A. C. Kanicki, R. A. Altschuler, W. M. King
JOURNAL OF NEUROPHYSIOLOGY
(2020)
Article
Ophthalmology
Natela Shanidze, Preeti Verghese
Article
Medicine, General & Internal
Courtney E. Stewart, Ariane C. Kanicki, David S. Bauer, Richard A. Altschuler, W. Michael King
Article
Neurosciences
Natela M. Shanidze, Anca Velisar
JOURNAL OF NEUROPHYSIOLOGY
(2020)
Review
Clinical Neurology
Courtney Elaine Stewart, Avril Genene Holt, Richard A. Altschuler, Anthony Thomas Cacace, Courtney D. Hall, Owen D. Murnane, W. Michael King, Faith W. Akin
FRONTIERS IN NEUROLOGY
(2020)
Article
Neurosciences
Courtney E. Stewart, David S. Bauer, Richard A. Altschuler, William Michael King
Summary: The study demonstrates that exposure to less intense noise can lead to temporary peripheral vestibular dysfunction that may recover within a short period of time. These findings suggest a correlation between the extent and duration of vestibular dysfunction with noise intensity and exposure duration.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Review
Neurosciences
Preeti Verghese, Cecile Vullings, Natela Shanidze
Summary: This article discusses the consequences of losing the foveal oculomotor reference on eye movements and how individuals adapt to using an eccentric fixation locus as a new oculomotor reference. Eye movements play a crucial role in everyday activities, but using an eccentric locus for fixation may impact certain tasks.
ANNUAL REVIEW OF VISION SCIENCE, VOL 7, 2021
(2021)
Article
Neurosciences
Natela M. Shanidze, Zachary Lively, Rachel Lee, Preeti Verghese
Summary: Macular degeneration (MD) leads to variability in the direction of saccades during pursuit, making them less appropriately directed. PRL eccentricity significantly correlates with an increase in saccades in non-target directions.
Article
Behavioral Sciences
Dylan Bartikofsky, Mikayla Jade Hertz, David S. Bauer, Richard Altschuler, W. Michael King, Courtney Elaine Stewart
Summary: This study examined the impact of noise exposure on motor performance in rats using a balance beam crossing task, and found that noise exposure significantly affected the rats' ability to perform the task.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2023)
Article
Psychology, Mathematical
Anca Velisar, Natela M. Shanidze
Summary: In this study, the Pupil Core, a head-mounted video-based eye tracking device, was systematically assessed for measurement uncertainty in three eye-tracking domains. The assessment included the 2D scene camera image, eye rotation relative to the scene camera 3D space, and the projection of gaze point location onto the target plane or world coordinates. The study also explored the importance of eye camera motion during active tasks and its impact on gaze detection alignment. The findings highlighted the impact of eye camera motion, inaccurate gaze point depth estimation, and erroneous eye models on data noise and emphasized the need for consistent eye models and additional reliability assessments in experiments utilizing eye movements and gaze point measurements.
BEHAVIOR RESEARCH METHODS
(2023)
Article
Psychology, Mathematical
Al Lotze, Kassia Love, Anca Velisar, Natela M. Shanidze
Summary: In this study, a low-cost robotic oculomotor simulator called EyeRobot was proposed to evaluate the performance of eye trackers and the effects of different oculomotor deficits on tracking accuracy and performance. The results showed that EyeRobot could simulate realistic eye movements and be tracked by a head-mounted eye tracker.
BEHAVIOR RESEARCH METHODS
(2022)
Meeting Abstract
Ophthalmology
Mustafa Safi, Preeti Verghese, Natela Shanidze
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2020)
Meeting Abstract
Ophthalmology
Natela Shanidze, Preeti Verghese
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)
Article
Neurosciences
Stephanie E. Haggerty, W. Michael King
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2018)