Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Functional Analysis of the Transmembrane and Cytoplasmic Domains of Pcdh15a in Zebrafish Hair Cells

(2017) Reo Maeda et al.   JOURNAL OF NEUROSCIENCE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Beyond Cell–Cell Adhesion: Sensational Cadherins for Hearing and Balance

(2017) Avinash Jaiganesh et al.   Cold Spring Harbor Perspectives in Biology

Molecular Identity of the Mechanotransduction Channel in Hair Cells: Not Quiet There Yet

(2016) Z. Wu et al.   JOURNAL OF NEUROSCIENCE

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

(2016) D. P. Corey et al.   JOURNAL OF NEUROSCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

An elastic element in the protocadherin-15 tip link of the inner ear

(2016) Raul Araya-Secchi et al.   Nature Communications

Cryo-EM single particle analysis with the Volta phase plate

(2016) Radostin Danev et al.   eLife

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

TMIE Is an Essential Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2014) Bo Zhao et al.   NEURON

The how and why of identifying the hair cell mechano-electrical transduction channel

(2014) Thomas Effertz et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Subunit determination of the conductance of hair-cell mechanotransducer channels

(2014) Maryline Beurg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2

(2014) R. Maeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

Multicolour Fluorescence-Detection Size-Exclusion Chromatography for Structural Genomics of Membrane Multiprotein Complexes

(2013) David Parcej et al.   PLoS One

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Use of knowledge-based restraints inphenix.refineto improve macromolecular refinement at low resolution

(2012) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Large Membrane Domains in Hair Bundles Specify Spatially Constricted Radixin Activation

(2012) H. Zhao et al.   JOURNAL OF NEUROSCIENCE

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction

(2012) Marcos Sotomayor et al.   NATURE

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

(2011) S. W. Webb et al.   DEVELOPMENT

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

On the combination of molecular replacement and single-wavelength anomalous diffraction phasing for automated structure determination

(2009) Santosh Panjikar et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanotransduction by Hair Cells: Models, Molecules, and Mechanisms

(2009) Peter G. Gillespie et al.   CELL

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

Gene structure and mutant alleles of PCDH15: nonsyndromic deafness DFNB23 and type 1 Usher syndrome

(2008) Zubair M. Ahmed et al.   HUMAN GENETICS

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE