Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

Precise multimodal optical control of neural ensemble activity

(2018) Alan R. Mardinly et al.   NATURE NEUROSCIENCE

Two-Photon Bidirectional Control and Imaging of Neuronal Excitability with High Spatial Resolution In Vivo

(2018) Angelo Forli et al.   Cell Reports

Axonal GABAA receptors depolarize presynaptic terminals and facilitate transmitter release in cerebellar Purkinje cells

(2017) Javier Zorrilla de San Martin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetic inhibition of behavior with anion channelrhodopsins

(2017) Farhan Mohammad et al.   NATURE METHODS

Temporally precise single-cell-resolution optogenetics

(2017) Or A. Shemesh et al.   NATURE NEUROSCIENCE

Chloride conducting light activated channel GtACR2 can produce both cessation of firing and generation of action potentials in cortical neurons in response to light

(2017) A.Y. Malyshev et al.   NEUROSCIENCE LETTERS

NKCC1 Chloride Importer Antagonists Attenuate Many Neurological and Psychiatric Disorders

(2017) Yehezkel Ben-Ari   TRENDS IN NEUROSCIENCES

The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance and Spectral Sensitivity

(2017) Elena G. Govorunova et al.   Scientific Reports

Optogenetic Neuronal Silencing in Drosophila during Visual Processing

(2017) Alex S. Mauss et al.   Scientific Reports

Biophysical constraints of optogenetic inhibition at presynaptic terminals

(2016) Mathias Mahn et al.   NATURE NEUROSCIENCE

Cellular resolution circuit mapping with temporal-focused excitation of soma-targeted channelrhodopsin

(2016) Christopher A Baker et al.   eLife

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity

(2015) Andre Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo

(2015) Jonas Wietek et al.   Scientific Reports

Equalizing excitation–inhibition ratios across visual cortical neurons

(2014) Mingshan Xue et al.   NATURE

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

(2014) Amy S Chuong et al.   NATURE NEUROSCIENCE

Structure-Guided Transformation of Channelrhodopsin into a Light-Activated Chloride Channel

(2014) A. Berndt et al.   SCIENCE

Conversion of Channelrhodopsin into a Light-Gated Chloride Channel

(2014) J. Wietek et al.   SCIENCE

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

(2013) John Y Lin et al.   NATURE NEUROSCIENCE

rAAV-Mediated Subcellular Targeting of Optogenetic Tools in Retinal Ganglion Cells In Vivo

(2013) Chaowen Wu et al.   PLoS One

Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission

(2012) Joseph V Raimondo et al.   NATURE NEUROSCIENCE

Axonal GABAA Receptors Increase Cerebellar Granule Cell Excitability and Synaptic Activity

(2011) J. R. Pugh et al.   JOURNAL OF NEUROSCIENCE

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Presynaptic GABAA receptors enhance transmission and LTP induction at hippocampal mossy fiber synapses

(2010) Arnaud Ruiz et al.   NATURE NEUROSCIENCE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

(2009) Tommy L Lewis et al.   NATURE NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Axonal GABAAreceptors

(2008) Federico F. Trigo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons Is Caused by the Na-K-2Cl Cotransporter NKCC1

(2008) S. Khirug et al.   JOURNAL OF NEUROSCIENCE