miR-146a promotes the initiation and progression of melanoma by activating Notch signaling

Using theRPackagecrlmmfor Genotyping and Copy Number Estimation

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miR-146a Inhibits Cell Growth, Cell Migration and Induces Apoptosis in Non-Small Cell Lung Cancer Cells

(2013) Gang Chen et al.   PLoS One

Genetic Variants in miRNAs Predict Bladder Cancer Risk and Recurrence

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Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

(2012) W.-B. Tsai et al.   CANCER RESEARCH

Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

(2012) L. Asnaghi et al.   CLINICAL CANCER RESEARCH

Melanoma: from mutations to medicine

(2012) H. Tsao et al.   GENES & DEVELOPMENT

The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma

(2012) Junji Yamashita et al.   MELANOMA RESEARCH

A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma

(2012) Raymond Wai-Ming Lung et al.   MOLECULAR CARCINOGENESIS

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer

(2012) Renata Hezova   WORLD JOURNAL OF GASTROENTEROLOGY

Down-regulation ofBRCA1expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers

(2011) Amandine I. Garcia et al.   EMBO Molecular Medicine

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA regulation of melanoma progression

(2011) Vanessa F. Bonazzi et al.   MELANOMA RESEARCH

Association between the rs2910164 polymorphism in pre-mir-146a and oral carcinoma progression

(2011) Pei-Shi Hung et al.   ORAL ONCOLOGY

Signatures of MicroRNAs and Selected MicroRNA Target Genes in Human Melanoma

(2010) D. Philippidou et al.   CANCER RESEARCH

The Myc-miR-17 92 Axis Blunts TGF  Signaling and Production of Multiple TGF -Dependent Antiangiogenic Factors

(2010) M. Dews et al.   CANCER RESEARCH

Lineage-Specific Transcriptional Regulation of DICER by MITF in Melanocytes

(2010) Carmit Levy et al.   CELL

Somatic alterations in the melanoma genome: A high-resolution array-based comparative genomic hybridization study

(2010) Andreas Gast et al.   GENES CHROMOSOMES & CANCER

Nuclear Factor-κB Contributes to Anaplastic Thyroid Carcinomas through Up-Regulation of miR-146a

(2010) Francesco Pacifico et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

(2010) Gideon Bollag et al.   NATURE

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

(2010) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

The effect of sequencing errors on metagenomic gene prediction

(2009) Katharina J Hoff   BMC GENOMICS

Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes

(2009) Chelsea C. Pinnix et al.   CANCER RESEARCH

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb

(2008) Wei Kuang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ErbB2 Induces Notch1 Activity and Function in Breast Cancer Cells

(2008) Jaime Lindsay et al.   CTS-Clinical and Translational Science

Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles

(2008) Geneviève Aubin-Houzelstein et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rational targeting of Notch signaling in cancer

(2008) P Rizzo et al.   ONCOGENE

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

(2008) K. Jazdzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA