Direct observation of frequency modulated transcription in single cells using light activation

Single-mRNA counting using fluorescent in situ hybridization in budding yeast

(2012) Tatjana Trcek et al.   Nature Protocols

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

Chromosomal Position Effects Are Linked to Sir2-Mediated Variation in Transcriptional Burst Size

(2011) Cory Batenchuk et al.   BIOPHYSICAL JOURNAL

General properties of transcriptional time series in Escherichia coli

(2011) Lok-hang So et al.   NATURE GENETICS

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics

(2011) D. M. Suter et al.   SCIENCE

Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene

(2011) D. R. Larson et al.   SCIENCE

Dynamic Analysis of Stochastic Transcription Cycles

(2011) Claire V. Harper et al.   PLOS BIOLOGY

Transcriptional Bursting from the HIV-1 Promoter Is a Significant Source of Stochastic Noise in HIV-1 Gene Expression

(2010) Abhyudai Singh et al.   BIOPHYSICAL JOURNAL

Methylation of H3K4 Is Required for Inheritance of Active Transcriptional States

(2010) Tetsuya Muramoto et al.   CURRENT BIOLOGY

Digital nature of the immediate-early transcriptional response

(2010) M. Stevense et al.   DEVELOPMENT

Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells

(2010) Amir Mor et al.   NATURE CELL BIOLOGY

Single-allele analysis of transcription kinetics in living mammalian cells

(2010) Sharon Yunger et al.   NATURE METHODS

A theoretical framework for gene induction and experimental comparisons

(2010) K. M. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones

(2010) R. B. Deal et al.   SCIENCE

HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency

(2010) Ron Skupsky et al.   PLoS Computational Biology

Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds

(2009) Hsien-Ming Lee et al.   ACS Chemical Biology

Imaging Transcription in Living Cells

(2009) Xavier Darzacq et al.   Annual Review of Biophysics

Extracting Kinetics Information from Single-Molecule Fluorescence Resonance Energy Transfer Data Using Hidden Markov Models

(2009) Tae-Hee Lee   JOURNAL OF PHYSICAL CHEMISTRY B

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas

(2009) Neil J. McKenna et al.   MOLECULAR ENDOCRINOLOGY

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

From DNA sequence to transcriptional behaviour: a quantitative approach

(2009) Eran Segal et al.   NATURE REVIEWS GENETICS

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

A single molecule view of gene expression

(2009) Daniel R. Larson et al.   TRENDS IN CELL BIOLOGY

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effects of Molecular Memory and Bursting on Fluctuations in Gene Expression

(2008) J. M. Pedraza et al.   SCIENCE