Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy

Somatic Expression of PyMT or Activated ErbB2 Induces Estrogen-Independent Mammary Tumorigenesis

(2015) Michael J. Toneff et al.   NEOPLASIA

STAT signaling in mammary gland differentiation, cell survival and tumorigenesis

(2013) S. Haricharan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Contribution of an alveolar cell of origin to the high-grade malignant phenotype of pregnancy-associated breast cancer

(2013) S Haricharan et al.   ONCOGENE

Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor

(2011) M. S. Redell et al.   BLOOD

Pregnancy-associated breast cancer

(2011) Virginia F. Borges et al.   CANCER

Stat5 assumes distinct functions in mammary gland development and mammary tumor formation

(2011) Vida Vafaizadeh   Frontiers in Bioscience-Landmark

Loss of Nuclear Localized and Tyrosine Phosphorylated Stat5 in Breast Cancer Predicts Poor Clinical Outcome and Increased Risk of Antiestrogen Therapy Failure

(2011) Amy R. Peck et al.   JOURNAL OF CLINICAL ONCOLOGY

Stat3 controls lysosomal-mediated cell death in vivo

(2011) Peter A. Kreuzaler et al.   NATURE CELL BIOLOGY

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

(2011) Traci R Lyons et al.   NATURE MEDICINE

MAPping out breast cancer chemoprevention

(2011) Lisa Hutchinson   Nature Reviews Clinical Oncology

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

(2010) A. Quintas-Cardama et al.   BLOOD

Cyclin D1 Kinase Activity Is Required for the Self-Renewal of Mammary Stem and Progenitor Cells that Are Targets of MMTV-ErbB2 Tumorigenesis

(2010) Rinath Jeselsohn et al.   CANCER CELL

Genetic manipulation of individual somatic mammary cells in vivo reveals a master role of STAT5a in inducing alveolar fate commitment and lactogenesis even in the absence of ovarian hormones

(2010) Jie Dong et al.   DEVELOPMENTAL BIOLOGY

Rate, molecular spectrum, and consequences of human mutation

(2010) M. Lynch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation

(2010) Jay P. Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival

(2010) T. W. Hand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired Turnover of Prolactin Receptor Contributes to Transformation of Human Breast Cells

(2009) A. Plotnikov et al.   CANCER RESEARCH

Lentivirus Vectors for Stably Introducing Genes into Mammary Epithelial Cells in Vivo

(2009) Wen Bu et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation

(2009) Xuejun Xu et al.   PLoS One

Oncogene-Mediated Inhibition of Glycogen Synthase Kinase 3  Impairs Degradation of Prolactin Receptor

(2008) A. Plotnikov et al.   CANCER RESEARCH

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

(2008) L. Hennighausen et al.   GENES & DEVELOPMENT

Jak2/Stat5 Signaling in Mammogenesis, Breast Cancer Initiation and Progression

(2008) Kay-Uwe Wagner et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE