ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast

DNA Replication Checkpoint Signaling Depends on a Rad53-Dbf4 N-Terminal Interaction in Saccharomyces cerevisiae

(2013) Y.-C. Chen et al.   GENETICS

Direct and Indirect Control of the Initiation of Meiotic Recombination by DNA Damage Checkpoint Mechanisms in Budding Yeast

(2013) Bilge Argunhan et al.   PLoS One

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)

(2013) S. Gray et al.   Open Biology

Budding Yeast ATM/ATR Control Meiotic Double-Strand Break (DSB) Levels by Down-Regulating Rec114, an Essential Component of the DSB-machinery

(2013) Jesús A. Carballo et al.   PLoS Genetics

A Central Coupler for Recombination Initiation Linking Chromosome Architecture to S Phase Checkpoint

(2012) Tomoichiro Miyoshi et al.   MOLECULAR CELL

Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes

(2012) Hannah G. Blitzblau et al.   PLoS Genetics

Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

(2011) Silvia Panizza et al.   CELL

Protection of repetitive DNA borders from self-induced meiotic instability

(2011) Gerben Vader et al.   NATURE

Surviving chromosome replication: the many roles of the S-phase checkpoint pathway

(2011) K. Labib et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatids

(2011) L. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Checkpoint mechanisms: the puppet masters of meiotic prophase

(2011) Amy J. MacQueen et al.   TRENDS IN CELL BIOLOGY

A Mec1- and PP4-Dependent Checkpoint Couples Centromere Pairing to Meiotic Recombination

(2010) Jill E. Falk et al.   DEVELOPMENTAL CELL

Processing of Meiotic DNA Double Strand Breaks Requires Cyclin-dependent Kinase and Multiple Nucleases

(2010) Nicola Manfrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Damage-induced phosphorylation of Sld3 is important to block late origin firing

(2010) Jaime Lopez-Mosqueda et al.   NATURE

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation

(2010) Philip Zegerman et al.   NATURE

Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae

(2009) Marie-Ange Teste et al.   BMC MOLECULAR BIOLOGY

Replicon Dynamics, Dormant Origin Firing, and Terminal Fork Integrity after Double-Strand Break Formation

(2009) Ylli Doksani et al.   CELL

Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation

(2009) L. I. Francis et al.   GENES & DEVELOPMENT

Regulation of Meiotic Recombination via Mek1-Mediated Rad54 Phosphorylation

(2009) Hengyao Niu et al.   MOLECULAR CELL

Phosphorylation of the Axial Element Protein Hop1 by Mec1/Tel1 Ensures Meiotic Interhomolog Recombination

(2008) Jesús A. Carballo et al.   CELL

Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination

(2008) H. Sasanuma et al.   GENES & DEVELOPMENT

Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast

(2008) L. Wan et al.   GENES & DEVELOPMENT

Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle

(2008) H. Cartagena-Lirola et al.   MOLECULAR AND CELLULAR BIOLOGY

The Multiple Roles of Cohesin in Meiotic Chromosome Morphogenesis and Pairing

(2008) Gloria A. Brar et al.   MOLECULAR BIOLOGY OF THE CELL

CDK targets Sae2 to control DNA-end resection and homologous recombination

(2008) Pablo Huertas et al.   NATURE