4.2 Article

Advances in the Evaluation and Management of Esophageal Disease of Systemic Sclerosis

Journal

CURRENT RHEUMATOLOGY REPORTS
Volume 17, Issue 1, Pages -

Publisher

SPRINGER
DOI: 10.1007/s11926-014-0475-y

Keywords

Systemic sclerosis; GERD; Esophageal reflux monitoring; Manometry; Impedance

Categories

Funding

  1. Public Health Service [RO1 DK079902, T32 DK101363-01]
  2. NIH-NIAMS [K23 AR059763]
  3. Scleroderma Research Foundation

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Symptoms of heartburn and dysphagia as well as objective findings of abnormal esophageal acid exposure and csophagcal dysmotility are common in patients with systemic sclerosis (SSc). Treatments for SSc esophageal disease are generally limited to gastrocsophagcal reflux disease (GERD) treatment with proton pump inhibitors. Progresses made in esophageal diagnostic testing offer the potential for improved clinical characterization of esophageal disease in SSc that may help direct management decisions. In addition to reviewing GERD management in patients with SSc, present and potential uses of endoscopy, reflux monitoring, manometry, impedance planimetry, and endoscopic ultrasound are discussed.

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