Article
Clinical Neurology
Praneeta Konduri, Amber Bucker, Anna Boers, Bruna Dutra, Noor Samuels, Kilian Treurniet, Olvert Berkhemer, Albert Yoo, Wim van Zwam, Robert van Oostenbrugge, Aad van der Lugt, Diederik Dippel, Yvo Roos, Joost Bot, Charles Majoie, Henk Marquering
Summary: This study aims to identify patient characteristics that are risk factors of late, subacute lesion growth. The study found that lower collateral capacity, longer time to treatment, unsuccessful recanalization, and larger midline shift were associated with late lesion growth.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Giancarlo Salsano, Giovanni Pracucci, Nicola Mavilio, Valentina Saia, Monica B. di Poggio, Laura Malfatto, Fabrizio Sallustio, Andrea Wlderk, Nicola Limbucci, Patrizia Nencini, Stefano Vallone, Andrea Zini, Guido Bigliardi, Mariano Velo, Isabella Francalanza, Paola Gennari, Rossana Tassi, Mauro Bergui, Paolo Cerrato, Giuseppe Carita, Cristiano Azzini, Roberto Gasparotti, Mauro Magoni, Salvatore Isceri, Christian Commodaro, Francesco Cordici, Roberto Menozzi, Lilia Latte, Mirco Cosottini, Michelangelo Mancuso, Alessio Comai, Enrica Franchini, Andrea Alexandre, Giacomo Della Marca, Edoardo Puglielli, Alfonsina Casalena, Francesco Causin, Claudio Baracchini, Luca Di Maggio, Andrea Naldi, Andrea Grazioli, Stefano Forlivesi, Luigi Chiumarulo, Marco Petruzzellis, Giuseppina Sanfilippo, Gianpaolo Toscano, Nicola Cavasin, Critelli Adriana, Maria Porzia Ganimede, Maria Pia Prontera, Giorgianni Andrea, Marco Mauri, William Auteri, Alfredo Petrone, Carlo Cirelli, Anne Falcou, Simona Corraine, Valeria Piras, Giuseppe Ganci, Tiziana Tassinari, Nunzio Paolo Nuzzi, Manuel Corato, Simona Sacco, Guido Squassina, Paolo Invernizzi, Ivan Gallesio, Delfina Ferrandi, Giovanni Dui, Gianluca Deiana, Pietro Amista, Monia Russo, Francesco Pintus, Antonio Baule, Giuseppe Craparo, Marina Mannino, Lucio Castellan, Danilo Toni, Salvatore Mangiafico
Summary: Complications of endovascular thrombectomy for large vessel occlusion strokes are not uncommon and may lead to poor clinical outcomes. Risk factors such as ongoing antiplatelet therapy, large vessel occlusion site, and demographic factors are associated with higher complication rates. Early recognition of these risk factors can help prevent and manage complications to maximize the benefits of endovascular thrombectomy.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Peripheral Vascular Disease
C. Venkata S. Ram, Sudhir Kumar, Pushpendra Nath Renjen, G. Praveen Kumar, Jayanthi Swaminathan, C. Rajesh Reddy, Sathyanarayana Kondati, Mukesh Sharma, V. L. Arul Selvan, Meenakshi Sundaram, Anupama Vasudevan, Daniel Lackland
Summary: The main risk factors for stroke in India are hypertension and diabetes, which need to be controlled and treated to prevent stroke.
JOURNAL OF HYPERTENSION
(2021)
Review
Geriatrics & Gerontology
Gang Deng, Yun-hui Chu, Jun Xiao, Ke Shang, Luo-Qi Zhou, Chuan Qin, Dai-Shi Tian
Summary: Endovascular therapy is the first-line treatment for acute ischemic stroke, but a phenomenon called futile recanalization still leads to poor functional recovery in nearly half of the treated patients. The complex pathophysiology of futile recanalization includes tissue no-reflow, early arterial reocclusion, poor collateral circulation, hemorrhagic transformation, impaired cerebrovascular autoregulation, and large hypoperfusion volume. Targeted therapy strategies have been researched, but further exploration is needed for translation to the bedside.
Article
Rehabilitation
Priyadarshini Pattath, Erika C. Odom, Xin Tong, Xiaoping Yin, Sallyann M. Coleman King
Summary: This study aimed to compare the factors associated with discharge of acute ischemic stroke survivors to inpatient rehabilitation (IRF) and skilled nursing facility (SNF) rehabilitation services. The results showed that patients discharged to SNF had longer hospital stays, more comorbidities, and higher modified Rankin scores compared to patients discharged to IRF. Nine characteristics were associated with a decreased likelihood of being discharged to IRF, while four characteristics were associated with an increased likelihood of being discharged to IRF. The study findings highlight the differences in demographic, clinical, and hospital characteristics between AIS patients receiving rehabilitation services in IRF and SNF.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Cardiac & Cardiovascular Systems
Matilda Hurskainen, Juho Tynkkynen, Markku Eskola, Terho Lehtimaki, Jussi Hernesniemi
Summary: This study aimed to investigate the risk factors for ischemic stroke (IS) after acute coronary syndromes (ACS). Based on a retrospective registry study of 8049 ACS patients, it was found that previous stroke, atrial fibrillation or flutter, and heart failure indicated by the Killip classification were the most significant risk factors for both early-onset and late-onset IS. Left ventricular ejection fraction and coronary artery disease severity were important risk factors for early-onset IS, while age and peripheral artery disease were important risk factors for late-onset IS. The CHA(2)DS(2)-VASc score and its components were strong predictors for both early-onset and late-onset IS.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Clinical Neurology
Linlin Fan, Wei Han, Yan Zhang, Meijun Zhou, Hong Ye, Weibi Chen, Yingying Su
Summary: Coronary heart disease, unconsciousness before EVT, elevated systolic blood pressure, and general anesthesia were identified as independent risk factors for early ineffective recanalization in patients with acute ischemic stroke receiving endovascular treatment.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Clinical Neurology
Stefania Nannoni, Ali Scherz-Moussa Youma, Michael Amiguet, Ashraf Eskandari, Davide Strambo, Patrik Michel
Summary: In this study, 2% of AIS patients were found to have no established vascular risk factors (EVRFs), who were typically younger with more multiterritorial strokes, and had strong associations with PFO and contraceptive use. These patients showed worse long-term outcomes in terms of adjusted functional outcome, recurrence, and death.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Oncology
Mirjana Mitrovic, Nikola Pantic, Nikica Sabljic, Zoran Bukumiric, Marijana Virijevic, Zlatko Pravdic, Mirjana Cvetkovic, Jovan Rajic, Jelena Bodrozic, Violeta Milosevic, Milena Todorovic-Balint, Ana Vidovic, Nada Suvajdzic-Vukovic, Darko Antic
Summary: Patients with acute myeloid leukemia (AML) have an increased risk of arterial thrombotic events (ATEs), especially if they have comorbidities, previous thrombosis, adverse cytogenetic risk, or a high BMI (>30).
Article
Geriatrics & Gerontology
Shilpa Krishnan, Ickpyo Hong, Grace Couture, Yi-Ting Tzen, Timothy Reistetter
Summary: This study examines the prevalence, comorbidities, and rehabilitation utilization of pressure injuries (PrIs) among older adults with stroke at skilled nursing facilities (SNFs). The findings suggest that individuals with a longer hospital stay, lower socioeconomic status, higher proportions of comorbidities, and higher functional impairments are more likely to present with PrIs at SNF admission assessment. Deep PrIs are associated with younger age, non-Hispanic Black ethnicity, lower socioeconomic status, shorter hospital stay, intensive care unit stay, higher functional impairments, skin integrity issues, system failure, and infections. The study also reveals differences in therapy utilization between individuals with different stages of PrIs.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Immunology
Shiting Tang, Liuyu Liu, Zhouhua Xie, Yaoqin He, Yunli Zhang, Yiju Xie, Shijian Chen, Yayuan Liu, Yunfei Wei, Zhijian Liang
Summary: This study identified independent risk factors for ischemic stroke in tubercular meningitis patients, including red blood cell distribution width, mean platelet volume, C-reactive protein, cerebrospinal fluid glucose, and Modified Research Council Grade II. The identification model established in this study may assist in monitoring tubercular meningitis patients at high risk of developing tubercular meningitis-related ischemic stroke.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Clinical Neurology
Andre Rego, Stefania Nannoni, Ali Scherz, Ashraf Eskandari, Alexander Salerno, Miguel Pereira, Davide Strambo, Patrik Michel
Summary: This retrospective study analyzed clinical data from patients with acute ischemic stroke and previously undiagnosed major vascular risk factors (UMRFs). Among these patients, 25.8% were newly diagnosed with at least one major risk factor, with the most common being hypertension, dyslipidemia, and atrial fibrillation. Compared to patients with previously diagnosed risk factors (DMRFs), UMRF patients were younger, more likely to smoke, and had more patent-foramen-ovale-related strokes.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Changling Li, Mengmeng Ma, Shuju Dong, Ye Hong, Jiajia Bao, Yang Zhang, Lijie Gao, Chaohua Cui, Jian Guo, Li He
Summary: The study found that there were no additional benefits of statin treatment in the acute phase for reducing post-stroke pneumonia among AIS patients. Statin treatment did not significantly increase the risk or severity of post-stroke pneumonia.
FRONTIERS IN NEUROLOGY
(2021)
Article
Nursing
Jianmiao Wang, Yuping Zhang, Yuanyuan Chen, Mei Li, Jingfen Jin
Summary: The feasibility and effectiveness of a nurse-led motor function rehabilitation program for patients with acute ischemic stroke were evaluated. The experimental group showed significantly higher postintervention Motor Assessment Scale and modified Barthel Index scores than the control group. The nurse-led rehabilitation program was feasible and effective in improving motor function for patients with acute ischemic stroke.
JOURNAL OF NURSING RESEARCH
(2022)
Article
Nursing
Tarja Tervo-Heikkinen, Anniina Heikkila, Marita Koivunen, Tiina Kortteisto, Jaana Peltokoski, Susanne Salmela, Merja Sankelo, Tuija Ylitormanen, Kristiina Junttila
Summary: This study explores the prevention of pressure injuries in Finnish acute inpatient care. The results show that risk assessments and preventive interventions for pressure injuries are irregularly conducted, highlighting the gaps in evidence-based nursing practice.
