Crystallographic insights into the structure–activity relationships of diazaborine enoyl-ACP reductase inhibitors

A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA

(2014) Huei-Jiun Li et al.   ACS Chemical Biology

Synthesis, Characterization, and Antibacterial Activity of Structurally Complex 2-Acylated 2,3,1-Benzodiazaborines and Related Compounds

(2014) Divya Kanichar et al.   CHEMISTRY & BIODIVERSITY

Rational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase Inhibitor

(2014) Johannes Schiebel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discrimination of Potent Inhibitors of Toxoplasma gondii Enoyl-Acyl Carrier Protein Reductase by a Thermal Shift Assay

(2013) Gustavo A. Afanador et al.   BIOCHEMISTRY

Activity of AFN-1252, a novel FabI inhibitor, againstStaphylococcus aureusin anin vitropharmacodynamic model simulating human pharmacokinetics

(2013) Brian T Tsuji et al.   JOURNAL OF CHEMOTHERAPY

JBluIce–EPICScontrol system for macromolecular crystallography

(2011) Sergey Stepanov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Is bacterial fatty acid synthesis a valid target for antibacterial drug discovery?

(2011) Joshua B Parsons et al.   CURRENT OPINION IN MICROBIOLOGY

Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 – 2010)

(2011) Xiaoyun Lu et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis

(2010) Kook-Han Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Diversity in enoyl-acyl carrier protein reductases

(2009) R. P. Massengo-Tiassé et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular basis for triclosan activity involves a flipping loop in the active site

(2009) Xiayang Qiu et al.   PROTEIN SCIENCE

Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway

(2008) Hao Lu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis, Characterization, and Antifungal Activity of Boron-Containing Thiosemicarbazones

(2008) Justin W. Hicks et al.   CHEMISTRY & BIODIVERSITY