Review
Veterinary Sciences
Camilla Luzzago, Nicola Decaro
Summary: Pestiviruses, including BVDV-1, BVDV-2, and HoBiPeV, are widely spread in cattle populations with high genetic variability, especially in Italy. This diversity may impact diagnostic tools and cross-protection from vaccines. Coordinated control measures are recommended in Italy.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Jose Rivas, Alesia Hasanaj, Caroline Deblon, Philippe Gisbert, Mutien-Marie Garigliany
Summary: This study aimed to determine the genetic diversity of BVDV strains currently circulating in France. By sampling and analyzing genetic sequences, the research found a higher genetic diversity of BVDV genotypes in France, including known genotypes and several new genotypes.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
N. S. Prosser, M. J. Green, E. Ferguson, M. J. Tildesley, E. M. Hill, M. J. Keeling, J. Kaler
Summary: Psychosocial factors such as trust and psychological proximity are associated with strategies for BVD control in UK cattle farmers. The psychological proximity to veterinarians is an important factor for proactive BVD control.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Veterinary Sciences
Yinghao Wu, Guangzhi Zhang, Hui Jiang, Ting Xin, Li Jia, Yichen Zhang, Yifei Yang, Tong Qin, Chuang Xu, Jie Cao, Gobena Ameni, Arfan Ahmad, Jiabo Ding, Limin Li, Yuzhong Ma, Xuezheng Fan
Summary: This study isolated and identified nine strains of BVDV from persistently infected cattle in China. The phylogenetic analysis showed that these new isolates were classified as the BVDV-1b subgenotype, sharing high homology with the CP7 strain. In addition, some genome variations and unique amino acid mutations were found in these new isolates. Further research on the virulence and pathogenesis of these new strains is recommended.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Anwar A. G. Al-Kubati, Mahmoud Kandeel, Jamal Hussen, Maged Gomaa Hemida, Abdullah I. A. Al-Mubarak
Summary: This study compared the protein antigenicity and pathogenicity of different BVDV genotypes and sub-genotypes using computational methods. Differences were identified between them, and the possibility of developing novel diagnostic assays and vaccines against BVDV was suggested.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Veterinary Sciences
Orla Shortall
Summary: This paper explores the lessons learned from bovine viral diarrhea (BVD) eradication schemes in Scotland and Ireland and applies the theoretical framework of co-productive governance to analyze stakeholder views. The results highlight the importance of clear goal narratives, engaging all actors, basing decisions on scientific research, and industry-government collaboration in achieving biosecurity goals.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Virology
Bin Tian, Dongjie Cai, Weiqiang Li, Qinglong Bu, Mingshu Wang, Gang Ye, Jianzhu Liu, Ya Wang, Liping Gou, Jun Yi, Zhicai Zuo
Summary: In 2019, diarrhea cases were reported on cattle farms in Qionglai and Guang'an, Sichuan Province. Two non-cytopathic strains of BVDV were isolated, with different genetic subtypes identified.
ARCHIVES OF VIROLOGY
(2021)
Article
Veterinary Sciences
Endeshaw Demil, Tsegaw Fentie, Gema Vidal, Wendi Jackson, Jennifer Lane, Sefinew Alemu Mekonnen, Woutrina Smith
Summary: The study found that the animal-level antibody prevalence of Bovine Viral Diarrhea Virus (BVDV) in the study area was 26.84%, and the herd-level seroprevalence was 68.3%. Logistic regression analysis identified age over 2 years, herd size over 11, and poor farm hygiene as potential risk factors associated with BVDV infection.
PREVENTIVE VETERINARY MEDICINE
(2021)
Review
Veterinary Sciences
Nuo Su, Qi Wang, Hong-Ying Liu, Lian-Min Li, Tian Tian, Ji-Ying Yin, Wei Zheng, Qing-Xia Ma, Ting-Ting Wang, Ting Li, Tie-Lin Yang, Jian-Ming Li, Nai-Chao Diao, Kun Shi, Rui Du
Summary: This meta-analysis investigates the prevalence and risk factors of bovine viral diarrhea (BVDV) worldwide in the past 10 years, aiming to provide reference and theoretical basis for BVDV control plans in different regions.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Immunology
Feng Pang, Qinqin Long, Min Wei
Summary: This article provides an overview of how bovine viral diarrhea virus (BVDV) evades the host's immune response through various immune evasion strategies, thereby promoting the virus's survival and replication. Understanding BVDV's immune evasion strategies can enhance our knowledge of its pathogenesis and contribute to the development of more effective prevention, control, and eradication measures.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Veterinary Sciences
Ninnet Gomez-Romero, Julia F. Ridpath, Francisco Javier Basurto-Alcantara, Antonio Verdugo-Rodriguez
Summary: Bovine viral diarrhea (BVD) is a globally-distributed infectious disease caused by bovine Pestiviruses, affecting cattle and other ruminant populations. The disease leads to economic losses in the cattle industry due to its wide range of clinical manifestations. In Mexico, studies have shown varying seroprevalence rates of BVDV, with at least four subgenotypes circulating in animal populations in the country.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Lorena Catalina Martinez-Rodriguez, Blanca Lisseth Guzman-Barragan, Diego Ordonez, Gabriel Andres Tafur-Gomez
Summary: This study investigated the seroprevalence and risk factors associated with Bovine Viral Diarrhea (BVD) in the Valledupar region of Colombia. It revealed a high seroprevalence of BVD and identified specific risk factors such as pasture lease, needle reuse, molasses supplementation, and native Creole breed. The presence of serological persistent cattle was also confirmed for the first time in Colombia.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Veterinary Sciences
Asami Nishimori, Shizuka Hirose, Saho Ogino, Kiyohiko Andoh, Norikazu Isoda, Yoshihiro Sakoda
Summary: This study genetically characterized 909 BVDV isolates obtained between 2014 and 2020 in Japan. The results showed that BVDV-1 and BVDV-2 were the predominant subtypes, and the major domestic clusters were consistent with previous studies. These findings provide updated information for appropriate vaccine selection.
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2022)
Article
Virology
Yusuke Goto, Gakuji Yaegashi, Kazuhiro Fukunari, Tohru Suzuki
Summary: Bovine viral diarrhea virus (BVDV) is a viral pathogen that causes serious issues in the cattle industry, with persistently infected cattle serving as sources of transmission. Acutely infected cattle generally recover, but there is a lack of information on the clinical characteristics. More data is needed for accurate diagnosis.
Article
Agriculture, Dairy & Animal Science
Xiaomei Yue, Wilma Steeneveld, Mariska van der Voort, Gerdien van Schaik, Johannes C. M. Vernooij, Linda van Duijn, Anouk M. B. Veldhuis, Henk Hogeveen
Summary: The study focused on the impact of introducing bovine viral diarrhea virus (BVDV) on milk production in dairy herds. Results showed that the reduction in milk yield was most significant in the first year after the introduction of BVDV, with relatively small effects in subsequent years. This study provides valuable insights for dairy farmers and policymakers on the quantitative effects of BVDV on milk production in a control program.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Entomology
Annalisa Andreani, Chiara Beltramo, Maria Paola Ponzetta, Antonio Belcari, Patrizia Sacchetti, Pier Luigi Acutis, Simone Peletto
Summary: This study aimed to characterize the bacterial communities of L. fortisetosa in different life stages. Results showed significant differences in composition and relative abundance of bacterial taxa among the groups. Pathogenic genera of concern for human health were detected, suggesting the potential role of L. fortisetosa as a reservoir of harmful microorganisms and the need for further investigation.
MEDICAL AND VETERINARY ENTOMOLOGY
(2023)
Article
Medicine, General & Internal
Aldo Pezzuto, Giuseppe Tonini, Massimo Ciccozzi, Pierfilippo Crucitti, Michela D'Ascanio, Fiammetta Cosci, Antonella Tammaro, Antonella Di Sotto, Teresa Palermo, Elisabetta Carico, Alberto Ricci
Summary: The aim of this study was to determine the benefits of smoking cessation combined with a single inhaler triple therapy in patients with COPD. The study found that 51% of patients successfully quit smoking within a month, and these patients showed better outcomes after six months compared to those who continued smoking, including improvements in lung function and physical activity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Virology
Serena Messali, Alessandro Rondina, Marta Giovanetti, Carlo Bonfanti, Massimo Ciccozzi, Arnaldo Caruso, Francesca Caccuri
Summary: During the COVID-19 pandemic, consensus genomic sequences were used to monitor the global spread of the virus quickly. However, there was less focus on intrahost genetic diversity. This study shows that intrahost single nucleotide variants (iSNVs) can be used for contact tracing analysis. The research demonstrates that iSNVs can propagate among individuals during the acute phase of infection, and transmission chains can be reconstructed by investigating iSNVs during SARS-CoV-2 outbreaks.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Virology
Anielly S. da Silva, Gabriel Montenegro de Campos, Marta Giovanetti, Victoria Simonatto Zucherato, Alex Ranieri Jeronimo Lima, Elaine Vieira Santos, Rodrigo Haddad, Massimo Ciccozzi, Luiz Carlos Junior Alcantara, Maria Carolina Elias, Sandra Coccuzzo Sampaio, Dimas Tadeu Covas, Simone Kashima, Svetoslav Nanev Slavov
Summary: In this study, metagenomics was used to identify viral infections among pediatric patients with acute respiratory disease. Two pools of samples were found to contain the little-known Malawi polyomavirus (MWPyV). Further testing revealed that MWPyV-positive samples also tested positive for respiratory syncytial virus. Phylogenetic analysis of MWPyV genome sequences from index samples was conducted, providing insights into its viral origin. This study represents the first molecular and genomic characterization of MWPyV in pediatric patients in South America.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Biology
Paola Dall'Ara, Stefania Lauzi, Jari Zambarbieri, Francesco Servida, Laura Barbieri, Roberto Rosenthal, Lauretta Turin, Elena Scarparo, Joel Filipe
Summary: Canine vaccination is crucial for preventing widespread diseases. Recommended vaccines include CPV-2, CDV, and CAdV-1. This study aimed to determine the levels of seroprotection in Italian dogs using the VacciCheck test.
Article
Veterinary Sciences
Paola Dall'Ara, Joel Filipe, Chiara Pilastro, Lauretta Turin, Stefania Lauzi, Elisa Maria Gariboldi, Damiano Stefanello
Summary: The life expectancy of pets has increased in recent years, but the incidence of cancer has also risen. This study aimed to investigate the effect of anticancer chemotherapy on the antibody response to core vaccines in dogs with cancer. The results showed that chemotherapy did not significantly suppress the post-vaccine antibody response.
VETERINARY SCIENCES
(2023)
Article
Microbiology
Monica Giammarioli, Maurilia Marcacci, Maria Teresa Scicluna, Antonella Cersini, Claudia Torresi, Valentina Curini, Massimo Ancora, Antonio Rinaldi, Marcello Giovanni Sala, Elisabetta Rossi, Cristina Casciari, Michela Pela, Claudia Pellegrini, Carmen Iscaro, Cesare Camma, Francesco Feliziani
Summary: In April 2022, the complete genome sequence of African swine fever virus (ASFV) genotype II, strain 20355/RM/2022_Italy, was identified in a wild boar in the city of Rome, Italy.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2023)
Review
Biochemistry & Molecular Biology
Sonia Moretti, Ivan Schietroma, Giuseppe Sberna, Maria Teresa Maggiorella, Leonardo Sernicola, Stefania Farcomeni, Marta Giovanetti, Massimo Ciccozzi, Alessandra Borsetti
Summary: HIV-1 replication in the gastrointestinal tract causes CD4+ T-cell depletion and disruption of the intestinal mucosa, leading to microbial translocation, inflammation, and immune activation. The gut serves as a viral reservoir with higher levels of HIV DNA compared to the blood. The interaction between HIV and key subsets of CD4+ T cells in the gut, as well as the role of gut microbiome and its metabolites in HIV-associated inflammation and immune activation, are important in the pathogenesis of HIV infection and related comorbidities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Fabio Scarpa, Ilenia Azzena, Alessandra Ciccozzi, Marta Giovanetti, Chiara Locci, Marco Casu, Pier Luigi Fiori, Alessandra Borsetti, Eleonora Cella, Miriana Quaranta, Stefano Pascarella, Daria Sanna, Massimo Ciccozzi, Igor Rogozin
Summary: The XBB.1.16 variant of SARS-CoV-2 has the potential to evade immune response but its evolutionary rate is slower than dangerous lineages. Structural analysis shows no significant differences from previous lineages, indicating no exceptional danger or high expansion capability. Continuous genome-based monitoring is important for understanding its descendants and other lineages.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Letter
Virology
Francesca Caccuri, Serena Messali, Fabio Scarpa, Marta Giovanetti, Massimo Ciccozzi, Arnaldo Caruso
JOURNAL OF MEDICAL VIROLOGY
(2023)
Letter
Virology
Fabio Scarpa, Massimo Ciccozzi
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Microbiology
Gabriele Ratti, Angelica Stranieri, Donatella Scavone, Alessandra Cafiso, Sara Meazzi, Camilla Luzzago, Paola Dall 'Ara, Filippo Tagliasacchi, Laura Cavicchioli, Francesco Ferrari, Alessia Giordano, Saverio Paltrinieri, Stefania Lauzi
Summary: The presence of a novel domestic cat hepadnavirus (DCH) in serum and peritoneal effusion samples from cats has been investigated. The study revealed the presence of DCH in cats with and without cavitary effusions, suggesting its potential role in hepatic diseases. Further research is needed to determine the pathogenicity of DCH in cats.
VETERINARY MICROBIOLOGY
(2023)
Review
Microbiology
Eleonora Cella, Marta Giovanetti, Francesca Benedetti, Fabio Scarpa, Catherine Johnston, Alessandra Borsetti, Giancarlo Ceccarelli, Taj Azarian, Davide Zella, Massimo Ciccozzi
Summary: Antibiotic resistance is a significant global health concern that requires a collaborative One Health approach. It poses a threat to human and animal health, as well as the effectiveness of medical treatments and veterinary interventions.
Article
Infectious Diseases
Gabriele Ratti, Alessia Facchin, Angelica Stranieri, Alessia Giordano, Saverio Paltrinieri, Paola Scarpa, Deborah Maragno, Alessia Gazzonis, Martina Penati, Camilla Luzzago, Paola Dall'Ara, Stefania Lauzi
Summary: This study aimed to investigate the presence and risk factors associated with the fecal carriage of ESBL/AmpC-producing E. coli in cats. Fecal samples from pet and stray cats were screened and confirmed for the presence of ESBL/AmpC-producing E. coli. Multidrug-resistant isolates were detected, and unhealthy cats and previous antibiotic therapy were significantly associated with fecal carriage of ESBL/AmpC-producing E. coli. These findings highlight the importance of antimicrobial stewardship and surveillance programs in companion animals, including stray cats.
Article
Veterinary Sciences
Paola Dall'Ara, Stefania Lauzi, Lauretta Turin, Giulia Castaldelli, Francesco Servida, Joel Filipe
Summary: This study measured the specific serum antibody titers against vaccine-preventable diseases in elderly dogs and found that more than half of the population were well protected. The larger elderly dogs were shown to be more protected than smaller ones. The study suggests considering closer vaccination for older dogs.
VETERINARY SCIENCES
(2023)