The Dynamic of the Apical Ectoplasmic Specialization between Spermatids and Sertoli Cells: The Case of the Small GTPase Rap1

Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca2+-dependent activation of platelet Rap1b GTPase

(2013) Gianni Francesco Guidetti et al.   BIOCHEMICAL JOURNAL

Differential Binding of RhoA, RhoB, and RhoC to Protein Kinase C-Related Kinase (PRK) Isoforms PRK1, PRK2, and PRK3: PRKs Have the Highest Affinity for RhoB

(2013) Catherine L. Hutchinson et al.   BIOCHEMISTRY

Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction

(2013) Magdalena Chrzanowska-Wodnicka   EXPERIMENTAL CELL RESEARCH

Human chorionic gonadotropin controls luteal vascular permeability via vascular endothelial growth factor by down-regulation of a cascade of adhesion proteins

(2013) Daniel Herr et al.   FERTILITY AND STERILITY

Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

(2013) Koji Ando et al.   JOURNAL OF CELL BIOLOGY

Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-β1

(2013) Mi-Young Moon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

RhoA, RhoB and RhoC have different roles in cancer cell migration

(2013) A.J. RIDLEY   JOURNAL OF MICROSCOPY

Rap-afadin axis in control of Rho signaling and endothelial barrier recovery

(2013) Anna A. Birukova et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor

(2012) Linlin Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells

(2012) Kathinka W. E. M. van Hooren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The association between CDC42 and caveolin-1 is involved in the regulation of capacitation and acrosome reaction of guinea pig and mouse sperm

(2012) R Baltiérrez-Hoyos et al.   REPRODUCTION

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

(2011) Willem-Jan Pannekoek et al.   CELLULAR SIGNALLING

Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids

(2011) Anna A. Birukova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of small GTPases at epithelial cell-cell junctions

(2011) Sandra Citi et al.   MOLECULAR MEMBRANE BIOLOGY

Regulating Rap small G-proteins in time and space

(2011) Martijn Gloerich et al.   TRENDS IN CELL BIOLOGY

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

Rap1A regulates generation of T regulatory cells via LFA-1-dependent and LFA-1-independent mechanisms

(2010) Lequn Li et al.   CELLULAR IMMUNOLOGY

Role of Afadin in Vascular Endothelial Growth Factor– and Sphingosine 1-Phosphate–Induced Angiogenesis

(2010) Hideto Tawa et al.   CIRCULATION RESEARCH

Signaling Role of Cdc42 in Regulating Mammalian Physiology

(2010) Jaime Melendez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

Ras and Rap Signaling in Synaptic Plasticity and Mental Disorders

(2010) Ruth L. Stornetta et al.   NEUROSCIENTIST

Sertoli-germ cell junctions in the testis: a review of recent data

(2010) I. A. Kopera et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cdc42 and Vesicle Trafficking in Polarized Cells

(2010) Kathryn P. Harris et al.   TRAFFIC

Regulation by Afadin of Cyclical Activation and Inactivation of Rap1, Rac1, and RhoA Small G Proteins at Leading Edges of Moving NIH3T3 Cells

(2009) Muneaki Miyata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis

(2009) V. T. Dao et al.   JOURNAL OF CELL SCIENCE

Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP

(2009) Anna A. Birukova et al.   MICROVASCULAR RESEARCH

Vascular Endothelial-Cadherin Stabilizes at Cell–Cell Junctions by Anchoring to Circumferential Actin Bundles through α- and β-Catenins in Cyclic AMP-Epac-Rap1 Signal-activated Endothelial Cells

(2009) Kazuomi Noda et al.   MOLECULAR BIOLOGY OF THE CELL

The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein Afadin

(2008) Yoshimi Takai et al.   Annual Review of Cell and Developmental Biology

Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

(2008) Willem-Jan Pannekoek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tubulobulbar Complexes Are Intercellular Podosome-Like Structures That Internalize Intact Intercellular Junctions During Epithelial Remodeling Events in the Rat Testis1

(2008) J'Nelle S. Young et al.   BIOLOGY OF REPRODUCTION

Meiotic progression of rat spermatocytes requires mitogen-activated protein kinases of Sertoli cells and close contacts between the germ cells and the Sertoli cells

(2008) Murielle Godet et al.   DEVELOPMENTAL BIOLOGY

E-cadherin dis-engagement activates the Rap1 GTPase

(2008) Sirisha Asuri et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector

(2008) Evanthia Aivatiadou et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Anchoring Junctions As Drug Targets: Role in Contraceptive Development

(2008) D. D. Mruk et al.   PHARMACOLOGICAL REVIEWS

Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis

(2008) E. W. P. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis

(2007) Elissa W.P. Wong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES