Pulmonary Arterial Hypertension in Adults: Novel Drugs and Catheter Ablation Techniques Show Promise? Systematic Review on Pharmacotherapy and Interventional Strategies

Vasoactive Intestinal Peptide in Pulmonary Arterial Hypertension

(2013) Nazzareno Galie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Addition of Sildenafil to Long-Term Intravenous Epoprostenol Therapy in Patients with Pulmonary Arterial Hypertension

(2013) Gérald Simonneau   ANNALS OF INTERNAL MEDICINE

Efficacy and Safety of Oral Treprostinil Monotherapy for the Treatment of Pulmonary Arterial Hypertension

(2013) Zhi-Cheng Jing et al.   CIRCULATION

Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial Hypertension

(2013) Marius M. Hoeper et al.   CIRCULATION

Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension

(2013) Shao-Liang Chen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

New Treatment Strategies for Pulmonary Arterial Hypertension

(2013) Nazzareno Galiè et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2013) Gerald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension

(2013) Tomás Pulido et al.   NEW ENGLAND JOURNAL OF MEDICINE

Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Riociguat for the Treatment of Pulmonary Arterial Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Percutaneous pulmonary artery denervation completely abolishes experimental pulmonary arterial hypertension in vivo

(2013) Shao-Liang Chen et al.   EuroIntervention

An Evaluation of Long-term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From the REVEAL Registry

(2012) Raymond L. Benza et al.   CHEST

Selexipag: an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension

(2012) Gérald Simonneau et al.   EUROPEAN RESPIRATORY JOURNAL

Targeting RhoA/ROCK pathway in pulmonary arterial hypertension

(2012) Sabina Antonela Antoniu   EXPERT OPINION ON THERAPEUTIC TARGETS

Combination Therapy Improves Exercise Capacity and Reduces Risk of Clinical Worsening in Patients With Pulmonary Arterial Hypertension

(2012) Bing Zhu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Atrial Septostomy in Patients with End-Stage Pulmonary Hypertension. No More Needles but Wires, Energy and Close Anatomical Definition

(2012) ROBERTO BAGLINI   JOURNAL OF INTERVENTIONAL CARDIOLOGY

Slow Receptor Dissociation Kinetics Differentiate Macitentan from Other Endothelin Receptor Antagonists in Pulmonary Arterial Smooth Muscle Cells

(2012) John Gatfield et al.   PLoS One

Meta-Analysis of Monotherapy Versus Combination Therapy for Pulmonary Arterial Hypertension

(2011) Benjamin D. Fox et al.   AMERICAN JOURNAL OF CARDIOLOGY

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

(2011) David Montani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long-term Treatment With Sildenafil Citrate in Pulmonary Arterial Hypertension

(2011) Lewis J. Rubin et al.   CHEST

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

(2011) Johannes-Peter Stasch et al.   CIRCULATION

Effect of atrial septostomy on the survival of patients with severe pulmonary arterial hypertension

(2011) J. Sandoval et al.   EUROPEAN RESPIRATORY JOURNAL

Pro-apoptotic effects of imatinib on PDGF-stimulated pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension

(2011) Kazufumi Nakamura et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension

(2011) Daryl O. Schwenke et al.   JOURNAL OF APPLIED PHYSIOLOGY

From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension

(2011) Roxane Paulin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

(2010) Hossein A. Ghofrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST

(2010) Jean-Yves Blay   CANCER TREATMENT REVIEWS

Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension

(2010) B. K. Dahal et al.   EUROPEAN RESPIRATORY JOURNAL

Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil

(2010) K. T. B. Mouchaers et al.   EUROPEAN RESPIRATORY JOURNAL

Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension

(2010) Hiroshi Fujita et al.   HEART AND VESSELS

Addition of Inhaled Treprostinil to Oral Therapy for Pulmonary Arterial Hypertension

(2010) Vallerie V. McLaughlin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Changing Paradigm of the Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

(2010) Ryuzo Ohno   Current Hematologic Malignancy Reports

Molecular and cellular bases of chronic myeloid leukemia

(2010) Yaoyu Chen et al.   Protein & Cell

Tadalafil Therapy for Pulmonary Arterial Hypertension

(2009) Nazzareno Galiè et al.   CIRCULATION

Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)

(2009) et al.   EUROPEAN HEART JOURNAL

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

(2009) F. Grimminger et al.   EUROPEAN RESPIRATORY JOURNAL

ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension

(2009) Vallerie V. McLaughlin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Circulating Angiogenic Precursors in Idiopathic Pulmonary Arterial Hypertension

(2008) Kewal Asosingh et al.   AMERICAN JOURNAL OF PATHOLOGY

Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension

(2008) Gerhard-Paul Diller et al.   CIRCULATION

Ambrisentan for the Treatment of Pulmonary Arterial Hypertension

(2008) Nazzareno Galiè et al.   CIRCULATION

Inhalation of vasoactive intestinal peptide in pulmonary hypertension

(2008) H. H. Leuchte et al.   EUROPEAN RESPIRATORY JOURNAL

Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial

(2008) N Galiè et al.   LANCET

Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension

(2008) Zhu JunHui et al.   RESPIRATORY MEDICINE