Aaptamines from the Marine SpongeAaptossp. Display Anticancer Activities in Human Cancer Cell Lines and Modulate AP-1-, NF-κB-, and p53-Dependent Transcriptional Activity in Mouse JB6 Cl41 Cells

ATF2: A transcription factor that elicits oncogenic or tumor suppressor activities

(2014) Anindita Bhoumik et al.   CELL CYCLE

Activity of aaptamine and two derivatives, demethyloxyaaptamine and isoaaptamine, in cisplatin-resistant germ cell cancer

(2013) Sergey A. Dyshlovoy et al.   Journal of Proteomics

The Extracts of Some Marine Invertebrates and Algae Collected off the Coast Waters of Vietnam Induce the Inhibitory Effects on the Activator Protein-1 Transcriptional Activity in JB6 Cl41 Cells

(2013) S. N. Fedorov et al.   Journal of Chemistry

ATF2 – at the crossroad of nuclear and cytosolic functions

(2012) Eric Lau et al.   JOURNAL OF CELL SCIENCE

Proteomic Profiling of Germ Cell Cancer Cells Treated with Aaptamine, a Marine Alkaloid with Antiproliferative Activity

(2012) Sergey A. Dyshlovoy et al.   JOURNAL OF PROTEOME RESEARCH

TCR stimulation upregulates MS4a4B expression through induction of AP-1 transcription factor during T cell activation

(2012) Yaping Yan et al.   MOLECULAR IMMUNOLOGY

A meta-analysis on alcohol drinking and gastric cancer risk

(2011) I. Tramacere et al.   ANNALS OF ONCOLOGY

Antiproliferative Effect of Aaptamine on Human Chronic Myeloid Leukemia K562 Cells

(2011) Meihua Jin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The anticancer activity of 3- and 10-bromofascaplysins is mediated by caspase-8, -9, -3-dependent apoptosis

(2010) Alexandra S. Kuzmich et al.   BIOORGANIC & MEDICINAL CHEMISTRY

AP-1 — The Jun proteins: Oncogenes or tumor suppressors in disguise?

(2010) Eitan Shaulian   CELLULAR SIGNALLING

Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-κB oncogenesis

(2010) A S Liss et al.   ONCOGENE

Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways

(2010) S-H Lee et al.   ONCOGENE

NF-κB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells

(2009) Alessandra Mangolini et al.   APOPTOSIS

NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy

(2009) Han-Ming Shen et al.   APOPTOSIS

Aaptamine and related products. Their isolation, chemical syntheses, and biological activity

(2009) Enrique L. Larghi et al.   TETRAHEDRON

Selectivity of the NF- B Response

(2009) R. Sen et al.   Cold Spring Harbor Perspectives in Biology

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Antiviral and Anticancer Optimization Studies of the DNA-binding Marine Natural Product Aaptamine

(2008) John J. Bowling et al.   Chemical Biology & Drug Design

Anticarcinogenesis by dietary phytochemicals: Cytoprotection by Nrf2 in normal cells and cytotoxicity by modulation of transcription factors NF-κB and AP-1 in abnormal cancer cells

(2007) Avanthika Gopalakrishnan et al.   FOOD AND CHEMICAL TOXICOLOGY