Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes

A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes

(2011) Ejaz Ahmad et al.   BIOCHIMIE

Correction

(2011) Ping Jiang et al.   BIOPHYSICAL JOURNAL

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

(2011) Pál Brasnyó et al.   BRITISH JOURNAL OF NUTRITION

Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy

(2011) Vincent T. Marchesi   FASEB JOURNAL

Resveratrol and health - A comprehensive review of human clinical trials

(2011) James M. Smoliga et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives

(2011) Seung-Jae Lee et al.   NEUROSCIENCE RESEARCH

Amyloid in the islets of Langerhans: Thoughts and some historical aspects

(2011) Per Westermark   UPSALA JOURNAL OF MEDICAL SCIENCES

Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer’s and Parkinson’s diseases

(2010) Tomohiro Nakamura et al.   APOPTOSIS

Design and study of peptide-based inhibitors of amylin cytotoxicity

(2010) Karen Muthusamy et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells

(2010) Karen Muthusamy et al.   BIOPOLYMERS

Polymorphism in Alzheimer Aβ Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape

(2010) Yifat Miller et al.   CHEMICAL REVIEWS

Islet amyloid polypeptide acts on glucose- stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca2+ concentration, and insulin secretion

(2010) Tiehong Zhu et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The Prion Diseases

(2010) Khalilah Brown et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

The Sulfated Triphenyl Methane Derivative Acid Fuchsin Is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation

(2010) Fanling Meng et al.   JOURNAL OF MOLECULAR BIOLOGY

Efficient Microwave-Assisted Synthesis of Human Islet Amyloid Polypeptide Designed to Facilitate the Specific Incorporation of Labeled Amino Acids

(2010) Peter Marek et al.   ORGANIC LETTERS

Ageing and protein aggregation-mediated disorders: from invertebrates to mammals

(2010) A. Dillin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Aβ and human amylin share a common toxicity pathwayviamitochondrial dysfunction

(2010) Yun-An Lim et al.   PROTEOMICS

Identifying and validating biomarkers for Alzheimer's disease

(2010) Christian Humpel   TRENDS IN BIOTECHNOLOGY

Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

(2010) Elina Zotova et al.   Alzheimers Research & Therapy

Evidence for Proteotoxicity in β Cells in Type 2 Diabetes

(2009) Tatyana Gurlo et al.   AMERICAN JOURNAL OF PATHOLOGY

Annexin A5 Directly Interacts with Amyloidogenic Proteins and Reduces Their Toxicity

(2009) Sahar Bedrood et al.   BIOCHEMISTRY

Amyloid inhibitors enhance survival of cultured human islets

(2009) Kathryn J. Potter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol

(2009) Rajesh Mishra et al.   CHEMBIOCHEM

Membrane permeabilization by Islet Amyloid Polypeptide

(2009) Maarten F.M. Engel   CHEMISTRY AND PHYSICS OF LIPIDS

Tetracycline Treatment Retards the Onset and Slows the Progression of Diabetes in Human Amylin/Islet Amyloid Polypeptide Transgenic Mice

(2009) J. F. Aitken et al.   DIABETES

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

(2009) S. Zraika et al.   DIABETOLOGIA

Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol

(2009) Diana Radovan et al.   FEBS LETTERS

Calcium-activated Calpain-2 Is a Mediator of Beta Cell Dysfunction and Apoptosis in Type 2 Diabetes

(2009) Chang-jiang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin☆

(2009) Stefania Rigacci et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Inhibition of IAPP and IAPP(20−29)Fibrillation by Polymeric Nanoparticles

(2009) C. Cabaleiro-Lago et al.   LANGMUIR

Are fibrilgrowth and membrane damage linked processes? An experimental and computational study of IAPP12–18and IAPP21–27peptides

(2009) Michele F. M. Sciacca et al.   NEW JOURNAL OF CHEMISTRY

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

(2009) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amylin Proprotein Processing Generates Progressively More Amyloidogenic Peptides that Initially Sample the Helical State†

(2008) Isaac T. Yonemoto et al.   BIOCHEMISTRY

Structure – Function Relationships of Pre-Fibrillar Protein Assemblies in Alzheimers Disease and Related Disorders

(2008) F. Rahimi et al.   Current Alzheimer Research

Islet Amyloid in Type 2 Diabetes, and the Toxic Oligomer Hypothesis

(2008) Leena Haataja et al.   ENDOCRINE REVIEWS

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

(2008) M. F. M. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: Implications for the study of amyloid formation

(2002) Melanie R. Nilsson et al.   PROTEIN SCIENCE