Review
Behavioral Sciences
Rachel A. Gilfarb, Benedetta Leuner
Summary: This article summarizes the effects of hormonal fluctuation on the female brain throughout the lifespan, with a focus on the changes in the GABA system. The functional impacts of these changes are discussed, along with potential avenues for further research to improve treatments for women experiencing brain function changes during hormonal transition periods.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Pharmacology & Pharmacy
Lan Yao, J. Carolyn Graff, Lotfi Aleya, Yan Jiao, Weikuan Gu, Geng Tian
Summary: Different human life stages have distinct physiological conditions and immune responses, and incorporating these life stages into medicine and drug usage can enhance the efficacy and precision of medication in disease treatment.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Danica H. Chang, Sandra M. Dumanski, Sofia B. Ahmed
Summary: Cardiovascular disease is the leading cause of death in women, yet females are underrepresented in cardiovascular research, leading to poorer health outcomes. A framework is proposed to address this issue by including female models, considering sex as a biological variable, and increasing female participation in clinical trials. It is essential to collect sex-specific data and stratify data by sex to ensure reproducibility and relevance of findings. Increasing female representation and considering female-specific cardiovascular risk factors will improve cardiovascular health for all.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Review
Obstetrics & Gynecology
Ramanarayana Boyapati, Sai Cherukuri, Ruparani Bodduru, Ambati Kiranmaye
Summary: The primary etiologic factor for periodontal diseases is dental plaque, but a susceptible host is also crucial, with hormonal levels being one of the contributing factors. Fluctuation in sex steroid hormones in females during different phases of their lifetime can have an exaggerated effect on the periodontium's response to dental plaque.
JOURNAL OF MID-LIFE HEALTH
(2021)
Article
Geriatrics & Gerontology
Weikuan Gu
Summary: There have been three major changes in human lifespan in the past half-century: decreased age of sexual maturity, slight increase in age of menopause/andropause, and a trend of increased life expectancy. Puberty and menopause are crucial life stages, with early puberty resulting in shorter lifespan and delayed menopause leading to longer lifespan. Strategies for increased lifespan have mainly focused on the post-reproductive stage, but they may face challenges and limitations. Therefore, it might be worth exploring the potential of delaying puberty and extending the period of body growth to achieve longer reproductive stages and a healthier lifespan.
REJUVENATION RESEARCH
(2022)
Article
Oncology
Elvin S. Cheng, Louiza S. Velentzis, Marianne Weber, Julia Steinberg, Karen Canfell, Xue Qin Yu
Summary: There is emerging evidence suggesting that oestrogen may be involved in lung cancer development, especially among never-smoking women. A large-scale study in China found that factors such as age at menarche, age at menopause, time since menopause, prior use of oral contraceptives, number of livebirths, breastfeeding, and age at first livebirth were associated with increased risk of lung cancer death among never-smoking women. These findings highlight the potential role of reproductive factors in lung cancer development.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Rheumatology
Liyi Dai, Dan Xu, Xinyi Li, Sicheng Huang, Xiangyue Duan, Ai Zheng, Jing Yang, Jie Zhao, Lin Zeng, Rong Mu
Summary: The study found that 31.8% of female patients with systemic sclerosis had reproductive health problems, with earlier menopausal age compared to national data. Reproductive health status was significantly associated with age of disease onset and digital ulcers.
Review
Obstetrics & Gynecology
Jiaxi Yang, Yiqing Song, Audrey J. Gaskins, Ling-Jun Li, Zhongwei Huang, Johan G. Eriksson, Frank B. Hu, Yap Seng Chong, Cuilin Zhang
Summary: This systematic review and meta-analysis indicates that adherence to the Mediterranean diet has positive effects on female reproductive health, particularly in reducing the risks of gestational diabetes mellitus and preterm birth. Additionally, following the Mediterranean diet may be associated with improved fertility and gestational weight management.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Fang Zhu, Hongchao Qi, Maxime Bos, Eric Boersma, Maryam Kavousi
Summary: This study found that female reproductive history is associated with the risk of heart failure, particularly with younger age at menarche, younger age at menopause, younger maternal age at first and last live birth, and having a higher number of children.
JACC-HEART FAILURE
(2023)
Review
Endocrinology & Metabolism
Michelle Maher, Lisa Owens
Summary: The COVID-19 pandemic has had a significant global impact, particularly affecting women. Studies have shown associations between the pandemic and menstrual cycle and psychological disturbances. Pregnancy increases the risk of severe COVID-19 disease. Furthermore, there are links between COVID-19 infection, vaccination, Long COVID syndrome, and reproductive health disturbances. However, research in this area is limited, with geographical variations and biases in published studies. Longitudinal population-based studies are needed to investigate further.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Reproductive Biology
M. A. Karadag, S. Schaefer-Somi, M. C. Demir, M. Kuru, S. Aslan, D. Kaya
Summary: This study investigated the clinical and hormonal effects of GnRH agonist application during the late-prepubertal stage. The results showed that it had an impact on hormone levels and cytological changes. These findings highlight the importance of accurate timing and breed-specific considerations when using GnRH agonists in late-prepubertal bitches.
Article
Ophthalmology
Donel S. Kelly, Sabhyta Sabharwal, David J. Ramsey, Melina I. Morkin
Summary: This review examines the effects of female sex hormone changes on corneal structure and function, including the hormonal milestones of menarche, pregnancy, and menopause, as well as the consequences of using exogenous sex hormones for fertility control and replacement therapy. Articles were identified through a search of PubMed, and the primary outcomes evaluated were changes in central corneal thickness, intraocular pressure, and tear film quality. The potential impact of hormone-associated changes on the diagnosis and surgical management of common eye diseases, as well as the potential use of sex hormones as therapeutic agents, is also discussed. Understanding the physiological effects of female sex hormones on the cornea is important for guiding management decisions related to ocular health throughout a woman's life stages.
Article
Oncology
Susan Luong, Claire Mockler, Jessica Pudwell, Wenbin Li, Jill Dudebout, Maria P. Velez
Summary: This study examined the effects of Hodgkin's lymphoma and its treatment on reproductive health in adolescent and young adult females. The risk of infertility and premature ovarian insufficiency was higher in Hodgkin's lymphoma patients, particularly those who received combined chemotherapy and radiotherapy. These findings highlight the importance of pre-treatment fertility counseling and reproductive health surveillance for AYAs diagnosed with Hodgkin's lymphoma.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Pharmacology & Pharmacy
Daniel J. Corsi, Malia S. Q. Murphy, Jocelynn Cook
Summary: Research indicates that cannabis may have effects on female reproductive health such as fertility, pregnancy outcomes, and menopause, but there is still a lack of comprehensive literature on this topic, especially in vulnerable populations like pregnant women, breastfeeding women, and infants. Further robust investigations into the potential risks of cannabis exposure on female reproductive health are needed.
CANNABIS AND CANNABINOID RESEARCH
(2021)
Article
Dermatology
L. Misery, S. Morisset, S. Seite, E. Brenaut, A. -S. Ficheux, J. W. Fluhr, V. Delvigne, C. Taieb
Summary: Sensitive skin is associated with factors such as sleep disorders, fatigue, and diet, as well as female hormonal status, pregnancy, and menstrual pain. These factors may play a role in neurogenic inflammation in sensitive skin.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
