Graphene oxide modified with aptamer-conjugated gold nanoparticles and heparin: a potent targeted anticoagulant

Uniform Ultrasmall Graphene Oxide Nanosheets with Low Cytotoxicity and High Cellular Uptake

(2013) Huan Zhang et al.   ACS Applied Materials & Interfaces

Nanomaterial-Based Fluorescent DNA Analysis: A Comparative Study of the Quenching Effects of Graphene Oxide, Carbon Nanotubes, and Gold Nanoparticles

(2013) Fan Li et al.   ADVANCED FUNCTIONAL MATERIALS

Binding Assistance Triggering Attachments of Hairpin DNA onto Gold Nanoparticles

(2013) Cheng Zhang et al.   ANALYTICAL CHEMISTRY

Thrombin inhibitors based on single-stranded DNA aptamers

(2013) Irina V. Gribkova et al.   BLOOD COAGULATION & FIBRINOLYSIS

Graphene-based materials biocompatibility: A review

(2013) Artur M. Pinto et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Novel thrombin and factor Xa inhibitors

(2013) Sean Yates et al.   CURRENT OPINION IN HEMATOLOGY

An update on recent patents on thrombin inhibitors (2010 – 2013)

(2013) Akul Y Mehta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

(2012) Bing Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemical Maturation of a Bivalent Aptamer by Single Domain Variation

(2012) Falk Rohrbach et al.   CHEMBIOCHEM

Functionalization of Graphene: Covalent and Non-Covalent Approaches, Derivatives and Applications

(2012) Vasilios Georgakilas et al.   CHEMICAL REVIEWS

Parenteral Anticoagulants

(2012) David A. Garcia et al.   CHEST

Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications

(2012) Anna Avino et al.   CURRENT PHARMACEUTICAL DESIGN

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer

(2012) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Adsorption of DNA onto gold nanoparticles and graphene oxide: surface science and applications

(2012) Juewen Liu   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

DNA-Length-Dependent Fluorescence Signaling on Graphene Oxide Surface

(2012) Po-Jung Jimmy Huang et al.   Small

The role of structural information in the discovery of direct thrombin and factor Xa inhibitors

(2012) Herbert Nar   TRENDS IN PHARMACOLOGICAL SCIENCES

Green and easy synthesis of biocompatible graphene for use as an anticoagulant

(2012) Yi Wang et al.   RSC Advances

DNA-Directed Self-Assembly of Graphene Oxide with Applications to Ultrasensitive Oligonucleotide Assay

(2011) Longhua Tang et al.   ACS Nano

Aptamer-conjugated nanomaterials and their applications

(2011) Liu Yang et al.   ADVANCED DRUG DELIVERY REVIEWS

Blood Compatible Graphene/Heparin Conjugate through Noncovalent Chemistry

(2011) Da Young Lee et al.   BIOMACROMOLECULES

Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals

(2011) Meghan A. Campbell et al.   CHEMICAL SOCIETY REVIEWS

Highly Efficient Control of Thrombin Activity by Multivalent Nanoparticles

(2011) Chia-Lun Hsu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Improving the Stability of Aptamers by Chemical Modification

(2011) R. E. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy

(2011) Joshua T. Robinson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures

(2011) Abhijit Rangnekar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Competing Interactions in DNA Assembly on Graphene

(2011) Saliha Akca et al.   PLoS One

Highly flexible and stable aptamer-caged nanoparticles for control of thrombin activity

(2011) Chia-Lun Hsu et al.   RSC Advances

Improved Synthesis of Graphene Oxide

(2010) Daniela C. Marcano et al.   ACS Nano

Aptamer-Conjugated Nanoparticles Efficiently Control the Activity of Thrombin

(2010) Yen-Chun Shiang et al.   ADVANCED FUNCTIONAL MATERIALS

Distribution and biocompatibility studies of graphene oxide in mice after intravenous administration

(2010) Xiaoyong Zhang et al.   CARBON

Engineering Dendritic Aptamer Assemblies as Superior Inhibitors of Protein Function

(2010) Youngmi Kim et al.   Chemistry-An Asian Journal

Direct thrombin inhibitors: pharmacology and application in intensive care medicine

(2010) Eva Schaden et al.   INTENSIVE CARE MEDICINE

Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood

(2010) Manash S. Chatterjee et al.   PLoS Computational Biology

Blood Coagulation: Hemostasis and Thrombin Regulation

(2009) Kenichi A. Tanaka et al.   ANESTHESIA AND ANALGESIA

Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function

(2009) Nicolas S. Petrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyvalent DNA Nanoparticle Conjugates Stabilize Nucleic Acids

(2008) Dwight S. Seferos et al.   NANO LETTERS

Molecular assembly for high-performance bivalent nucleic acid inhibitor

(2008) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombin generation, fibrin clot formation and hemostasis

(2008) Alisa S. Wolberg et al.   TRANSFUSION AND APHERESIS SCIENCE