Enzyme responsive materials: design strategies and future developments

Phosphatase responsive peptide surfaces

(2012) Mischa Zelzer et al.   JOURNAL OF MATERIALS CHEMISTRY

Live Monitoring of Cargo Release From Peptide-Based Hybrid Nanocapsules Induced by Enzyme Cleavage

(2012) Julien Andrieu et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Thermosensitive Peptide-Hybrid ABC Block Copolymers Obtained by ATRP: Synthesis, Self-Assembly, and Enzymatic Degradation

(2012) Albert J. de Graaf et al.   MACROMOLECULES

Sequence/structure relationships in aromatic dipeptide hydrogels formed under thermodynamic control by enzyme-assisted self-assembly

(2012) Meghan Hughes et al.   Soft Matter

Charge complementary enzymatic reconfigurable polymeric nanostructures

(2012) Pier-Francesco Caponi et al.   Soft Matter

Biological stimuli and biomolecules in the assembly and manipulation of nanoscale polymeric particles

(2012) Lyndsay M. Randolph et al.   Chemical Science

Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules

(2011) Anuradha Biswas et al.   ACS Nano

Multiplex Sensing of Protease and Kinase Enzyme Activity via Orthogonal Coupling of Quantum Dot–Peptide Conjugates

(2011) Stuart B. Lowe et al.   ACS Nano

Matrix metalloproteinase-sensitive thermogelling polymer for bioresponsive local drug delivery

(2011) Vivek Kumar Garripelli et al.   Acta Biomaterialia

Stimuli-responsive LbL capsules and nanoshells for drug delivery

(2011) Mihaela Delcea et al.   ADVANCED DRUG DELIVERY REVIEWS

Controlled Protein Delivery Based on Enzyme-Responsive Nanocapsules

(2011) Jing Wen et al.   ADVANCED MATERIALS

Functional Materials for Rechargeable Batteries

(2011) Fangyi Cheng et al.   ADVANCED MATERIALS

A sensitive colorimetric label-free assay for trypsin and inhibitor screening with gold nanoparticles

(2011) Wangxin Xue et al.   ANALYST

Intermolecular and Intramolecular Quencher Based Quantum Dot Nanoprobes for Multiplexed Detection of Endonuclease Activity and Inhibition

(2011) Yong Huang et al.   ANALYTICAL CHEMISTRY

A sensitive and selective quantum dots-based FRET biosensor for the detection of cancer marker type IV collagenase

(2011) Hongying Liu et al.   Analytical Methods

Quantum-Dot-Based FRET Detection of Histone Acetyltransferase Activity

(2011) James E. Ghadiali et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme-Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports

(2011) Carmen Coll et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalent Nanoparticle Networks as Ultrasensitive Enzyme Sensors

(2011) Roberto de laRica et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Nanoparticles Consisting of Lipopeptides and Fluorescein-Modified Polyanions for Monitoring of Protein Kinase Activity

(2011) Haruka Koga et al.   BIOCONJUGATE CHEMISTRY

Selective Enzymatic Degradation of Self-Assembled Particles from Amphiphilic Block Copolymers Obtained by the Combination ofN-Carboxyanhydride and Nitroxide-Mediated Polymerization

(2011) Gijs J. M. Habraken et al.   BIOMACROMOLECULES

Single-step kinase inhibitor screening using a peptide-modified gold nanoparticle platform

(2011) Shalini Gupta et al.   CHEMICAL COMMUNICATIONS

Bio-functionalisation to enzymatically control the solution properties of a self-supporting polymeric material

(2011) Paul D. Thornton et al.   CHEMICAL COMMUNICATIONS

Enzyme-directed assembly and manipulation of organic nanomaterials

(2011) Michael E. Hahn et al.   CHEMICAL COMMUNICATIONS

A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particles

(2011) Wenru Zhao et al.   CHEMICAL COMMUNICATIONS

Enzyme-Inspired Controlled Release of Cucurbit[7]uril Nanovalves by Using Magnetic Mesoporous Silica

(2011) Jinshui Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Guest-Release Control in Enzyme-Sensitive, Amphiphilic-Dendrimer-Based Nanoparticles through Photochemical Crosslinking

(2011) Krishna R. Raghupathi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multiplex Detection of Endonucleases by Using a Multicolor Gold Nanobeacon

(2011) Yong Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cytosine-phosphodiester-guanine oligodeoxynucleotide (CpG ODN)-capped hollow mesoporous silica particles for enzyme-triggered drug delivery

(2011) Yufang Zhu et al.   DALTON TRANSACTIONS

Review paper: Progress in the Field of Conducting Polymers for Tissue Engineering Applications

(2011) Anca-Dana Bendrea et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Hollow Mesoporous Silica/Poly(l-lysine) Particles for Codelivery of Drug and Gene with Enzyme-Triggered Release Property

(2011) Yufang Zhu et al.   Journal of Physical Chemistry C

Controlling and Switching the Morphology of Micellar Nanoparticles with Enzymes

(2011) Ti-Hsuan Ku et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Site Specific, Protease Cleavable, Hydrophobic Peptide–Polymer Nanoparticles

(2011) Matthias Maier et al.   MACROMOLECULES

Enzyme-Induced Formation of Thermoreversible Micellar Gels from Aqueous Solutions of Multiresponsive Hydrophilic ABA Triblock Copolymers

(2011) Jeremiah W. Woodcock et al.   MACROMOLECULES

Enzymatically degradable nanogels by inverse miniemulsion copolymerization of acrylamide with dextran methacrylates as crosslinkers

(2011) Daniel Klinger et al.   Polymer Chemistry

Dual enzymes regulate the molecular self-assembly of tetra-peptide derivatives

(2011) Jie Gao et al.   Soft Matter

Protease-promoted drug delivery using peptide-functionalized gold nanoparticles

(2011) Jianhao Wang et al.   Soft Matter

Biocatalytic self-assembly of 2D peptide-based nanostructures

(2011) Meghan Hughes et al.   Soft Matter

Switching of self-assembly in a peptide nanostructure with a specific enzyme

(2011) Matthew J. Webber et al.   Soft Matter

A self-immolative dendritic glucuronide prodrug of doxorubicin

(2011) Marion Grinda et al.   MedChemComm

Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs)

(2011) Shann S Yu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Protein Kinase-Actuated Resonance Energy Transfer in Quantum Dot−Peptide Conjugates

(2010) James E. Ghadiali et al.   ACS Nano

Enzyme-Responsive Intracellular Controlled Release Using Nanometric Silica Mesoporous Supports Capped with “Saccharides”

(2010) Andrea Bernardos et al.   ACS Nano

Nanotechnology-Enabled Closed Loop Insulin Delivery Device: In Vitro and In Vivo Evaluation of Glucose-Regulated Insulin Release for Diabetes Control

(2010) Claudia R. Gordijo et al.   ADVANCED FUNCTIONAL MATERIALS

Glucose-Responsive Bioinorganic Nanohybrid Membrane for Self-Regulated Insulin Release

(2010) Claudia R. Gordijo et al.   ADVANCED FUNCTIONAL MATERIALS

Self-Assembled DNA Hydrogels with Designable Thermal and Enzymatic Responsiveness

(2010) Yongzheng Xing et al.   ADVANCED MATERIALS

Protease sensing with nanoparticle based platforms

(2010) Katharina Welser et al.   ANALYST

Label-Free Fluorescent Detection of Protein Kinase Activity Based on the Aggregation Behavior of Unmodified Quantum Dots

(2010) Xiahong Xu et al.   ANALYTICAL CHEMISTRY

A Spatially Propagating Biochemical Reaction

(2010) Xiaoli Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Programmable Shape-Shifting Micelles

(2010) Miao-Ping Chien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Enzyme-Responsive Polymeric Superamphiphile

(2010) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry

(2010) Maarten van Dijk et al.   BIOMACROMOLECULES

Protease degradable tethers for controlled and cell-mediated release of nanoparticles in 2- and 3-dimensions

(2010) Talar Tokatlian et al.   BIOMATERIALS

An optical biosensing platform for proteinase activity using gold nanoparticles

(2010) Yao-Chen Chuang et al.   BIOMATERIALS

Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran–hyaluronic acid conjugates for cartilage tissue engineering

(2010) R. Jin et al.   BIOMATERIALS

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

Enzyme-instructed self-assembly of peptide derivatives to form nanofibers and hydrogels

(2010) Yuan Gao et al.   BIOPOLYMERS

Exploiting biocatalysis in peptide self-assembly

(2010) Richard J. Williams et al.   BIOPOLYMERS

A rapid and sensitive “add-mix-measure” assay for multiple proteinases based on one gold nanoparticle–peptide–fluorophore conjugate

(2010) Xiaohui Wang et al.   BIOSENSORS & BIOELECTRONICS

Sulfhydryl-based dendritic chain reaction

(2010) Eran Sella et al.   CHEMICAL COMMUNICATIONS

Micelle to fibre biocatalytic supramolecular transformation of an aromatic peptide amphiphile

(2010) Jan W. Sadownik et al.   CHEMICAL COMMUNICATIONS

Bioresponsive peptide–inorganic hybrid nanomaterials

(2010) Daniel Aili et al.   CHEMICAL SOCIETY REVIEWS

Applications of peptide and protein-based materials in bionanotechnology

(2010) Roberto de la Rica et al.   CHEMICAL SOCIETY REVIEWS

Next-generation peptide nanomaterials: molecular networks, interfaces and supramolecular functionality

(2010) Mischa Zelzer et al.   CHEMICAL SOCIETY REVIEWS

Injectable enzymatically crosslinked hydrogel system with independent tuning of mechanical strength and gelation rate for drug delivery and tissue engineering

(2010) Motoichi Kurisawa et al.   JOURNAL OF MATERIALS CHEMISTRY

Rate Enhancement of an Interfacial Biochemical Reaction through Localization of Substrate and Enzyme by an Adaptor Domain

(2010) Jing Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Thin Film Detection/Response System for Pathogenic Bacteria

(2010) Jin Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Specific Dual Enzyme-Mediated Payload Release from Peptide-Coated Silica Particles

(2010) Paul D. Thornton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEGylated Amyloid Peptide Nanocontainer Delivery and Release System

(2010) V. Castelletto et al.   LANGMUIR

Hydrogels for the Detection and Management of Protease Levels

(2010) Alison G. Patrick et al.   MACROMOLECULAR BIOSCIENCE

Synthesis and Characterization of Enzymatically Degradable PEG-Based Peptide-Containing Hydrogels

(2010) Jiyuan Yang et al.   MACROMOLECULAR BIOSCIENCE

Probing Protein Kinase (CK2) and Alkaline Phosphatase with CdSe/ZnS Quantum Dots

(2010) Ronit Freeman et al.   NANO LETTERS

Biocatalytic induction of supramolecular order

(2010) Andrew R. Hirst et al.   Nature Chemistry

Novel trimethyl lock based enzyme switch for the self-assembly and disassembly of gold nanoparticles

(2010) Rongrong Liu et al.   NEW JOURNAL OF CHEMISTRY

Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline)

(2010) Pier-Francesco Caponi et al.   Polymer Chemistry

Self-immolative linkers in polymeric delivery systems

(2010) Christopher A. Blencowe et al.   Polymer Chemistry

Bioartificial matrices for therapeutic vascularization

(2010) Edward A. Phelps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subtilases: The superfamily of subtilisin-like serine proteases

(2010) Roland J. Siezen et al.   PROTEIN SCIENCE

Kinase-Actuated Immunoaggregation of Peptide-Conjugated Gold Nanoparticles

(2010) Shalini Gupta et al.   Small

Controlling Cell Behavior Through the Design of Polymer Surfaces

(2010) Natália M. Alves et al.   Small

Lipase-supported synthesis of peptidic hydrogels

(2010) Laura Chronopoulou et al.   Soft Matter

A Simple, Universal Colorimetric Assay for Endonuclease/Methyltransferase Activity and Inhibition Based on an Enzyme-Responsive Nanoparticle System

(2009) Guangtao Song et al.   ACS Nano

Biotransformation on Polymer-Peptide Conjugates: A Versatile Tool to Trigger Microstructure Formation

(2009) Hans Kühnle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biotin-Avidin as a Protease-Responsive Cap System for Controlled Guest Release from Colloidal Mesoporous Silica

(2009) Axel Schlossbauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme-Responsive Controlled Release Using Mesoporous Silica Supports Capped with Lactose

(2009) Andrea Bernardos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of thermostable FMN-dependent NADH azoreductase from the moderate thermophile Geobacillus stearothermophilus

(2009) Ken’ichiro Matsumoto et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Activity-Linked Labeling of Enzymes by Self-Immolative Polymers

(2009) Roy Weinstain et al.   BIOCONJUGATE CHEMISTRY

Human Neutrophil Elastase Responsive Delivery from Poly(ethylene glycol) Hydrogels

(2009) Alex A. Aimetti et al.   BIOMACROMOLECULES

Stimuli-responsive interfaces and systems for the control of protein–surface and cell–surface interactions

(2009) Martin A. Cole et al.   BIOMATERIALS

Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery

(2009) Alex A. Aimetti et al.   BIOMATERIALS

Enhanced cytotoxicity of a polymer–drug conjugate with triple payload of paclitaxel

(2009) Rotem Erez et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Enzymatic activation of hydrophobic self-immolative dendrimers: The effect of reporters with ionizable functional groups

(2009) Michal Avital-Shmilovici et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparative Enzymatic Analysis of Azoreductases fromBacillussp. B29

(2009) Toshihiko OOI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

PEGylation modulates the interfacial kinetics of proteases on peptide-capped gold nanoparticles

(2009) Paul Free et al.   CHEMICAL COMMUNICATIONS

Colorimetric screening of bacterial enzyme activity and inhibition based on the aggregation of gold nanoparticles

(2009) Tingting Jiang et al.   CHEMICAL COMMUNICATIONS

Real-time monitoring of drug release

(2009) Roy Weinstain et al.   CHEMICAL COMMUNICATIONS

Proteinase-mediated drastic morphological change of peptide–amphiphile to induce supramolecular hydrogelation

(2009) Daisuke Koda et al.   CHEMICAL COMMUNICATIONS

An Adaptor Domain-Mediated Autocatalytic Interfacial Kinase Reaction

(2009) Xiaoli Liao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Exploiting SERS Hot Spots for Disease-Specific Enzyme Detection

(2009) R. C. Maher et al.   Journal of Physical Chemistry C

Making “smart polymers” smarter: Modern concepts to regulate functions in polymer science

(2009) Hans G. Börner et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Enzymatically Triggered Self-Assembly of Block Copolymers

(2009) Roey J. Amir et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sensing Caspase 3 Activity with Quantum Dot−Fluorescent Protein Assemblies

(2009) Kelly Boeneman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Triggered Disassembly of Dendrimer-Based Amphiphilic Nanocontainers

(2009) Malar A. Azagarsamy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme Responsive Nanocontainers with Cyclodextrin Gatekeepers and Synergistic Effects in Release of Guests

(2009) Chiyoung Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous Colorimetric Assay for Acetylcholinesterase and Inhibitor Screening with Gold Nanoparticles

(2009) Ming Wang et al.   LANGMUIR

Enzyme-Activated RGD Ligands on Functionalized Poly(ethylene glycol) Monolayers: Surface Analysis and Cellular Response

(2009) Simon J. Todd et al.   LANGMUIR

Self-Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

(2009) Adam Blanazs et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Protein Nanocapsule Weaved with Enzymatically Degradable Polymeric Network

(2009) Zhen Gu et al.   NANO LETTERS

Future perspectives and recent advances in stimuli-responsive materials

(2009) Debashish Roy et al.   PROGRESS IN POLYMER SCIENCE

Proteolytic Fluorescent Signal Amplification on Gold Nanoparticles for a Highly Sensitive and Rapid Protease Assay

(2009) Joong H. Kim et al.   Small

Branched peptide actuators for enzyme responsive hydrogel particles

(2009) Tom O. McDonald et al.   Soft Matter

Enzymatic Hydrogelation of Small Molecules

(2008) Zhimou Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enzymatically crosslinked carboxymethylcellulose–tyramine conjugate hydrogel: Cellular adhesiveness and feasibility for cell sheet technology

(2008) Shinji Sakai et al.   Acta Biomaterialia

Stimuli-Responsive Polymeric Systems for Biomedical Applications

(2008) J. F. Mano   ADVANCED ENGINEERING MATERIALS

Enzyme-Responsive Nanoparticle Systems

(2008) James E. Ghadiali et al.   ADVANCED MATERIALS

Energy Transfer-Based Multiplexed Assay of Proteases by Using Gold Nanoparticle and Quantum Dot Conjugates on a Surface

(2008) Young-Pil Kim et al.   ANALYTICAL CHEMISTRY

High-Tech Applications of Self-Assembling Supramolecular Nanostructured Gel-Phase Materials: From Regenerative Medicine to Electronic Devices

(2008) Andrew R. Hirst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Near-Infrared-Fluorescence-Quenched Gold-Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination

(2008) Seulki Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides – A model for biofunctional scaffolds

(2008) Ying Chau et al.   BIOMATERIALS

The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential

(2008) Olayiwola A. Adekoya et al.   Chemical Biology & Drug Design

A combined SPS–LCD sensor for screening protease specificity

(2008) Louise S. Birchall et al.   CHEMICAL COMMUNICATIONS

Cell adhesive hydrogels synthesised by copolymerisation of arg-protected Gly-Arg-Gly-Asp-Ser methacrylate monomers and enzymatic deprotection

(2008) Lynne Perlin et al.   CHEMICAL COMMUNICATIONS

Time-modulated Release of Multiple Proteins from Enzyme-responsive Multilayered Capsules

(2008) Yuki Itoh et al.   CHEMISTRY LETTERS

Self-Immolative Comb-Polymers: Multiple-Release of Side-Reporters by a Single Stimulus Event

(2008) Roy Weinstain et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hollow DNA/PLL microcapsules with tunable degradation property as efficient dual drug delivery vehicles by α-chymotrypsin degradation

(2008) Zhongjun Wang et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Enzyme-Responsive Snap-Top Covered Silica Nanocontainers

(2008) Kaushik Patel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Switchable Electrode Controlled by Enzyme Logic Network System: Approaching Physiologically Regulated Bioelectronics

(2008) Marina Privman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetics of Enzyme Attack on Substrates Covalently Attached to Solid Surfaces: Influence of Spacer Chain Length, Immobilized Substrate Surface Concentration and Surface Charge

(2008) Joseph Deere et al.   LANGMUIR

Synthesis and enzymatic cleavage of dual-ligand quantum dots

(2008) Sarah L. Sewell et al.   Materials Science & Engineering C-Materials for Biological Applications

Protease-Triggered Unveiling of Bioactive Nanoparticles

(2008) Todd J. Harris et al.   Small

Exploiting Enzymatic (Reversed) Hydrolysis in Directed Self-Assembly of Peptide Nanostructures

(2008) Apurba K. Das et al.   Small

Enzymatic hydrogelation to immobilize an enzyme for high activity and stability

(2008) Qigang Wang et al.   Soft Matter

Enzyme-responsive hydrogel particles for the controlled release of proteins: designing peptide actuators to match payload

(2008) Paul D. Thornton et al.   Soft Matter

An injectable enzymatically crosslinked hyaluronic acid–tyramine hydrogel system with independent tuning of mechanical strength and gelation rate

(2008) Fan Lee et al.   Soft Matter

Tryptophan-contained peptide-functional nanomaterials as general spectrofluorometric reagents for enzyme

(2008) Shu Jun Zhen et al.   TALANTA

Enzymatic Control of the Size of DNA Block Copolymer Nanoparticles

(2007) Fikri E. Alemdaroglu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoimprint lithography based fabrication of shape-specific, enzymatically-triggered smart nanoparticles

(2007) Luz Cristal Glangchai et al.   JOURNAL OF CONTROLLED RELEASE