Journal
ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 3, Issue 4, Pages 462-465Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201400010
Keywords
bromoenals; cyclocondensation; dihydropyridinones; imines; N-heterocyclic carbenes
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Funding
- National Science Foundation of China [21272237]
- Ministry of Science and Technology of China [2011CB808600]
- Chinese Academy of Sciences
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The N-heterocyclic carbene-catalyzed enantioselective [3+3] cyclocondensation of bromoenals and ketimines was developed. The reaction gives the corresponding dihydropyridinones in high yields with high enantioselectivity.
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