Article
Materials Science, Multidisciplinary
Muteb H. Alshammari, Ahmed Onayzan Alshammari, Mohamed Tharwat Elabbasy, Rafat Zreiq, M. A. El-Morsy, A. A. Menazea, M. F. H. Abd El-Kader
Summary: In order to enhance the antimicrobial potential of hydroxyapatite (HAp), it has been incorporated into various nanocomposites (NCs) with different structures. The HAp/tungsten oxide/graphene oxide (GO) ternary nanocomposite shows an improved cell viability of 96.7 +/-3% for osteoblast cells. Analytical techniques such as XRD, FTIR, XPS, and EDS confirm the chemical compositions. The HAp/WO3/GO composite exhibits a significant improvement in anti-microbial activity with 85.6 +/- 1.6% and 110.1 +/- 2.0% for E. coli and S. aureus, respectively.
RESULTS IN PHYSICS
(2023)
Article
Engineering, Multidisciplinary
Daniela Predoi, Simona Liliana Iconaru, Steluta Carmen Ciobanu, Nicolas Buton, Mihai Valentin Predoi
Summary: A magnesium-doped hydroxyapatite in chitosan matrix (MgHApC) sample, obtained through coprecipitation, showed potential for various applications in pharmaceutical, medical, and food industries. The sample exhibited good antimicrobial properties in vitro and showed promise for future biomedical applications.
Review
Chemistry, Multidisciplinary
Xianwen Wang, Xiaoyan Zhong, Jianxiang Li, Zhuang Liu, Liang Cheng
Summary: Inorganic nanomaterials have great potential in biomedicine, but long-term accumulation in healthy tissues can cause toxicity. The emergence of biodegradable and clearable inorganic nanomaterials provides a way to prevent such toxicity, and a comprehensive understanding of their design and metabolic pathways is essential for expanding therapeutic applications for various diseases.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
Svetlana Kotova, Sergei Kostjuk, Yuri Rochev, Yuri Efremov, Anastasia Frolova, Peter Timashev
Summary: Smart thermoresponsive polymers, such as PNIPAM, have great potential for biomedical applications, but face challenges such as low biodegradability and drug loading capacity. Combining natural polymers with PNIPAM can overcome these issues and create dual-functional materials. However, the addition of hydrophobic and hydrophilic fragments to PNIPAM can affect its transition temperature. This review focuses on the use of natural polymers, including polysaccharides, fibrous and non-fibrous proteins, and DNA, in combination with PNIPAM for biomedical purposes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Ceramics
D. Muthu, G. Suresh Kumar, M. Gowri, M. Prasath, V. Viswabaskaran, V. S. Kattimani, E. K. Girija
Summary: Researchers have shown interest in using eggshells to synthesize nanocrystalline hydroxyapatite with suitable nanoscale characteristics by adjusting reaction parameters, choosing appropriate preparation methods, and utilizing organic modifiers. Rapid synthesis of eggshell derived HA with different organic modifiers using a custom built microwave reactor can be a potential approach for the rapid preparation of precursor materials for bone fillers, drug delivery carriers, tissue engineering scaffolds, and other biomedical applications.
CERAMICS INTERNATIONAL
(2022)
Review
Chemistry, Analytical
Sinem Orbay, Ozgur Kocaturk, Rana Sanyal, Amitav Sanyal
Summary: Molecularly imprinted polymers (MIPs) are functional materials with unique characteristics, such as high stability, simple preparation, robustness, better binding capacity, and low cost. By integrating MIPs with inorganic nanoparticles, highly multifunctional materials can be obtained, which have a wide range of biomedical applications.
Review
Biotechnology & Applied Microbiology
Shanghui Huang, Xiangqian Hong, Mingyi Zhao, Nanbo Liu, Huiling Liu, Jun Zhao, Longquan Shao, Wei Xue, Han Zhang, Ping Zhu, Rui Guo
Summary: Nanomaterials and hydrogels have significant application value in biomedicine. Nanocomposite hydrogel systems can overcome their respective shortcomings and have broad prospects for application.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2022)
Review
Chemistry, Multidisciplinary
Pedro Lavrador, Marco R. Esteves, Vitor M. Gaspar, Joao F. Mano
Summary: Recent advances in the design of stimuli-responsive nanocomposite hydrogels have expanded their potential for operating as advanced systems in various biomedical applications, benefitting from tailored single or multi-responsiveness. The combination of hydrogels and nanoparticles showcases an intrinsic ability to react to external or internal/physiological stimuli, developing intelligent systems with application-oriented features.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Pharmacology & Pharmacy
Carla Serri, Iriczalli Cruz-Maya, Irene Bonadies, Giovanna Rassu, Paolo Giunchedi, Elisabetta Gavini, Vincenzo Guarino
Summary: Significant advances in nanotechnologies have enabled the design of innovative devices suitable for biomedical applications, through increasing knowledge and refining of technical practices in green chemistry and bioengineering. New bio-sustainable methodologies are developing to fabricate drug delivery systems that combine properties of materials and bioactive molecules efficiently, meeting the demands of the health market. This work provides an overview of recent developments in bio-fabrication methods for designing green platforms, emphasizing their impact on biomedical and pharmaceutical applications.
Review
Polymer Science
Diego Cuartas-Marulanda, Laura Forero Cardozo, Adriana Restrepo-Osorio, Patricia Fernandez-Morales
Summary: Magnesium alloys have unique properties but degrade easily when in contact with body fluids, hence the need for protective coatings. This review focuses on the application of natural biopolymer coatings and modification techniques on magnesium alloys, and compares them with inorganic coatings in terms of corrosion resistance, cell adhesion, proliferation, and biodegradability.
Article
Engineering, Biomedical
A. Harini, Sharon P. S. Sofini, Deepika Balasubramanian, Agnishwar Girigoswami, Koyeli Girigoswami
Summary: Nanocomposites, including natural and synthetic polymer nanocomposites, have emerged as important biomaterials with prominent medical applications. These materials possess high stability, non-immunogenicity, sustained drug delivery, and can be widely used in medical implants, wound healing, and bone repair.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2023)
Review
Polymer Science
Maria Puertas-Bartolome, Ana Mora-Boza, Luis Garcia-Fernandez
Summary: Natural polymers have been widely used in biomedical applications for their resemblance to native tissues and biocompatibility, although they lack mechanical strength. Recent advances in biofabrication techniques such as 3D printing and microfluidics allow for the manufacturing of complex polymer matrixes with properties similar to the extracellular matrix, offering the possibility of incorporating different cell lines for tissue regeneration applications.
Article
Polymer Science
Ruijie Tang, Xiaoxue Yao, Jingyi Chen, Sreepathy Sridar, Xianglei He, Yuan Pu, Jie-Xin Wang, Dan Wang, Steven Wang
Summary: By encapsulating modified zirconia nanoparticles in PUA-based hybrid films, both hardness and refractive index of the materials can be significantly enhanced. Successful manipulation of the interfacial reaction conditions between nanoparticles and PUA film results in nanocomposites with ultrahigh hardness and superior refractive index.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Ameya Sharma, Ishnoor Kaur, Divya Dheer, Manju Nagpal, Pradeep Kumar, D. Nagasamy Venkatesh, Vivek Puri, Inderbir Singh
Summary: Numerous compounds in the oceans have extensive applications in biomedical and biotechnological fields, which make them a prime renewable source of natural substances and promote the development of novel medical systems and devices. Polysaccharides, abundantly present in the marine ecosystem, have advantages such as low extraction costs, solubility in extraction media, interactions with biological compounds, and the ability to be modified for various shapes and sizes. These properties have led to their use as raw materials for drug delivery carrier systems.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Karen Lilian Hernandez-Ruiz, Jaime Lopez-Cervantes, Dalia Isabel Sanchez-Machado, Maria del Rosario Martinez-Macias, Ma. Araceli Correa-Murrieta, Ana Sanches-Silva
Summary: This review discusses the environmental deterioration caused by solid waste generated during industrial fish processing and explores the utilization of hydroxyapatite (HAp) extracted from this waste. HAp, a compound similar to human bone, has been extensively studied and developed for biomedical material applications.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2022)
Article
Biotechnology & Applied Microbiology
Kaveh Kurd, Amir Ahmad Khandagi, Soodabeh Davaran, Abolfazl Akbarzadeh
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2016)
Article
Pharmacology & Pharmacy
Abdolrahim Abbaszad Rafi, Mehrdad Mahkam, Soodabeh Davaran, Hamed Hamishehkar
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2016)
Article
Biochemistry & Molecular Biology
Ali Jahanban-Esfahlan, Siavoush Dastmalchi, Soodabeh Davaran
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2016)
Article
Materials Science, Biomaterials
Fatemeh Asghari, Roya Salehi, Marziyeh Agazadeh, Effat Alizadeh, Khosro Adibkia, Mohammad Samiei, Abolfazl Akbarzadeh, Negar Abbasi Aval, Soodabeh Davaran
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2016)
Article
Pharmacology & Pharmacy
H. Danafar, K. Rostamizadeh, S. Davaran, M. Hamidi
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2017)
Review
Biotechnology & Applied Microbiology
Fatemeh Gorjikhah, Soodabeh Davaran, Roya Salehi, Mohsen Bakhtiari, Arash Hasanzadeh, Yunes Panahi, Masumeh Emamverdy, Abolfazl Akbarzadeh
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
Soheila Motaali, Maryam Pashaeiasl, Abolfazl Akbarzadeh, Soodabeh Davaran
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2017)
Review
Biotechnology & Applied Microbiology
Nahideh Asadi, Soodabeh Davaran, Yunes Panahi, Arash Hasanzadeh, Javad Malakootikhah, Hadi Fallah Moafi, Abolfazl Akbarzadeh
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2017)
Review
Biotechnology & Applied Microbiology
Fatemeh Asghari, Mohammad Samiei, Khosro Adibkia, Abolfazl Akbarzadeh, Soodabeh Davaran
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2017)
Review
Biotechnology & Applied Microbiology
Sonia Fathi Karkan, Majid Mohammadhosseini, Yunes Panahi, Morteza Milani, Nosratollah Zarghami, Abolfazl Akbarzadeh, Elham Abasi, Arastoo Hosseini, Soodabeh Davaran
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2017)
Review
Biotechnology & Applied Microbiology
Saeid Shabestari Khiabani, Masoud Farshbaf, Abolfazl Akbarzadeh, Soodabeh Davaran
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2017)
Article
Chemistry, Physical
Soodabeh Davaran, Aliyeh Ghamkhari, Effat Alizadeh, Bakhshali Massoumi, Mehdi Jaymand
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2017)
Review
Materials Science, Biomaterials
Sepideh Zununi Vahed, Roya Salehi, Soodabeh Davaran, Simin Sharifi
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2017)
Article
Biotechnology & Applied Microbiology
Eommolbanin Ebrahimi, Amir Ahmad Khandaghi, Fereshteh Valipour, Soraia Babaie, Fatemeh Asghari, Soheila Motaali, Elham Abbasi, Abolfazl Akbarzadeh, Soodabeh Davaran
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2016)
Review
Chemistry, Medicinal
Bahar Khalandi, Nahideh Asadi, Morteza Milani, Soodabeh Davaran, Azam Jafari Najaf Abadi, Elham Abasi, Abolfazl Akbarzadeh