The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness

(2012) Nuno Raimundo et al.   CELL

Modular recognition of nucleic acids by PUF, TALE and PPR proteins

(2012) Aleksandra Filipovska et al.   Molecular BioSystems

C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation

(2012) Bas F. J. Wanschers et al.   NUCLEIC ACIDS RESEARCH

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome

(2012) Joanna Rorbach et al.   NUCLEIC ACIDS RESEARCH

Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases

(2011) Tsutomu Suzuki et al.   Annual Review of Genetics

Human diseases with impaired mitochondrial protein synthesis

(2011) Agnès Rötig   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Traces of post-transcriptional RNA modifications in deep sequencing data

(2011) Sven Findeiß et al.   BIOLOGICAL CHEMISTRY

The Human Mitochondrial Transcriptome

(2011) Tim R. Mercer et al.   CELL

Processing mitochondrial (t)RNAs: New enzyme, old job

(2011) Walter Rossmanith et al.   CELL CYCLE

RNA processing in a tiny transcriptome

(2011) Christiane Kupsch et al.   CELL CYCLE

RNA processing in human mitochondria

(2011) Maria I.G. Lopez Sanchez et al.   CELL CYCLE

Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

(2011) Elena J. Tucker et al.   Cell Metabolism

MTERF4 Regulates Translation by Targeting the Methyltransferase NSUN4 to the Mammalian Mitochondrial Ribosome

(2011) Yolanda Cámara et al.   Cell Metabolism

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

(2011) Benedetta Ruzzenente et al.   EMBO JOURNAL

Termination of Protein Synthesis in Mammalian Mitochondria

(2011) Zofia M. A. Chrzanowska-Lightowlers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revisiting the Yeast PPR Proteins—Application of an Iterative Hidden Markov Model Algorithm Reveals New Members of the Rapidly Evolving Family

(2011) Kamil A. Lipinski et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural Basis for Dimerization and Activity of Human PAPD1, a Noncanonical Poly(A) Polymerase

(2011) Yun Bai et al.   MOLECULAR CELL

Pentatricopeptide Repeat Proteins Stimulate mRNA Adenylation/Uridylation to Activate Mitochondrial Translation in Trypanosomes

(2011) Inna Aphasizheva et al.   MOLECULAR CELL

Structure of human mitochondrial RNA polymerase

(2011) Rieke Ringel et al.   NATURE

The evolution of RNA editing and pentatricopeptide repeat genes

(2011) Sota Fujii et al.   NEW PHYTOLOGIST

Protein-mediated protection as the predominant mechanism for defining processed mRNA termini in land plant chloroplasts

(2011) Petya Zhelyazkova et al.   NUCLEIC ACIDS RESEARCH

Short non-coding RNA fragments accumulating in chloroplasts: footprints of RNA binding proteins?

(2011) Hannes Ruwe et al.   NUCLEIC ACIDS RESEARCH

TEFM (c17orf42) is necessary for transcription of human mtDNA

(2011) Michal Minczuk et al.   NUCLEIC ACIDS RESEARCH

A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression

(2011) Inge Kühl et al.   NUCLEIC ACIDS RESEARCH

PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria

(2011) Joanna Rorbach et al.   NUCLEIC ACIDS RESEARCH

Localization of Human RNase Z Isoforms: Dual Nuclear/Mitochondrial Targeting of the ELAC2 Gene Product by Alternative Translation Initiation

(2011) Walter Rossmanith   PLoS One

Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription

(2011) Y. V. Surovtseva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection patterns on restorer-like genes reveal a conflict between nuclear and mitochondrial genomes throughout angiosperm evolution

(2011) S. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

(2011) Lien K. Brzezniak et al.   RNA Biology

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

(2011) O. Rackham et al.   RNA

The Bicoid Stability Factor Controls Polyadenylation and Expression of Specific Mitochondrial mRNAs in Drosophila melanogaster

(2011) Ana Bratic et al.   PLoS Genetics

Structure of transfer RNAs: similarity and variability

(2011) Richard Giegé et al.   Wiley Interdisciplinary Reviews-RNA

Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs

(2011) Suzuki Tsutomu et al.   Wiley Interdisciplinary Reviews-RNA

Defective Mitochondrial mRNA Maturation Is Associated with Spastic Ataxia

(2010) Andrew H. Crosby et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LRPPRC is a mitochondrial matrix protein that is conserved in metazoans

(2010) Fredrik H. Sterky et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit

(2010) Sven Dennerlein et al.   BIOCHEMICAL JOURNAL

Translation termination in human mitochondrial ribosomes

(2010) Ricarda Richter et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The human mitochondrial replication fork in health and disease

(2010) Sjoerd Wanrooij et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Human mitochondrial mRNAs—like members of all families, similar but different

(2010) Richard J. Temperley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

RNA turnover in human mitochondria: More questions than answers?

(2010) Lukasz S. Borowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

DMR1 (CCM1/YGR150C) of Saccharomyces cerevisiae Encodes an RNA-Binding Protein from the Pentatricopeptide Repeat Family Required for the Maintenance of the Mitochondrial 15S Ribosomal RNA

(2010) O. Puchta et al.   GENETICS

Current Views of the Structure of the Mammalian Mitochondrial Ribosome

(2010) Emine C. Koc et al.   ISRAEL JOURNAL OF CHEMISTRY

Mitochondrial and Nuclear Genomic Responses to Loss ofLRPPRCExpression

(2010) Vishal M. Gohil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

NOA1 is an essential GTPase required for mitochondrial protein synthesis

(2010) Mateusz Kolanczyk et al.   MOLECULAR BIOLOGY OF THE CELL

The energetics of genome complexity

(2010) Nick Lane et al.   NATURE

RNA sequencing: advances, challenges and opportunities

(2010) Fatih Ozsolak et al.   NATURE REVIEWS GENETICS

A single Arabidopsis organellar protein has RNase P activity

(2010) Anthony Gobert et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

(2010) Takeshi Uchiumi et al.   NUCLEIC ACIDS RESEARCH

Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition

(2010) Mateusz Wydro et al.   NUCLEIC ACIDS RESEARCH

Unique features of animal mitochondrial translation systems

(2010) Kimitsuna WATANABE   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Mechanism of RNA stabilization and translational activation by a pentatricopeptide repeat protein

(2010) J. Prikryl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hungry Codons Promote Frameshifting in Human Mitochondrial Ribosomes

(2010) R. Temperley et al.   SCIENCE

Evidence for an Active Role of IF3mtin the Initiation of Translation in Mammalian Mitochondria†

(2009) Brooke E. Christian et al.   BIOCHEMISTRY

Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome

(2009) Metodi D. Metodiev et al.   Cell Metabolism

Something Old, Something New, Something Borrowed …

(2009) Eric A. Shoubridge   Cell Metabolism

Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation

(2009) Stefan M.K. Davies et al.   FEBS LETTERS

Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness

(2009) Justin Cotney et al.   HUMAN MOLECULAR GENETICS

Human Mitochondrial SUV3 and Polynucleotide Phosphorylase Form a 330-kDa Heteropentamer to Cooperatively Degrade Double-stranded RNA with a 3′-to-5′ Directionality

(2009) Dennis Ding-Hwa Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

tRNA recognition, processing, and disease: Hypotheses around an unorthodox type of RNase P in human mitochondria

(2009) Johann Holzmann et al.   MITOCHONDRION

EF-G2mt Is an Exclusive Recycling Factor in Mammalian Mitochondrial Protein Synthesis

(2009) Masafumi Tsuboi et al.   MOLECULAR CELL

Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome

(2009) Woranontee Weraarpachai et al.   NATURE GENETICS

Construction of Parallel Analysis of RNA Ends (PARE) libraries for the study of cleaved miRNA targets and the RNA degradome

(2009) Marcelo A German et al.   Nature Protocols

Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells

(2009) Oliver Rackham et al.   NUCLEIC ACIDS RESEARCH

Meta-analysis of small RNA-sequencing errors reveals ubiquitous post-transcriptional RNA modifications

(2009) H. Alexander Ebhardt et al.   NUCLEIC ACIDS RESEARCH

Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance

(2009) Roman J. Szczesny et al.   NUCLEIC ACIDS RESEARCH

Unconventional decoding of the AUA codon as methionine by mitochondrial tRNA Met with the anticodon f 5 CAU as revealed with a mitochondrial in vitro translation system

(2009) Chie Takemoto et al.   NUCLEIC ACIDS RESEARCH

Biogenesis of glutaminyl-mt tRNAGln in human mitochondria

(2009) A. Nagao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial DNA replication and repair: all a flap

(2009) Ian J. Holt   TRENDS IN BIOCHEMICAL SCIENCES

A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

(2009) Joshua M. Baughman et al.   PLoS Genetics

Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochromebexpression and a marked reduction in ubiquinol–cytochromecreductase activity in mouse heart mitochondria

(2008) Fenghao Xu et al.   BIOCHEMICAL JOURNAL

Polyadenylation and degradation of mRNA in mammalian mitochondria: a missing link?: Table 1

(2008) Agnieszka J. Bobrowicz et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Polyadenylation in mammalian mitochondria: Insights from recent studies

(2008) Takashi Nagaike et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

(2008) Johann Holzmann et al.   CELL

hNOA1 Interacts with Complex I and DAP3 and Regulates Mitochondrial Respiration and Apoptosis

(2008) Tingdong Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single Mammalian Mitochondrial Translation Initiation Factor Functionally Replaces Two Bacterial Factors

(2008) Rahul Gaur et al.   MOLECULAR CELL

Global identification of microRNA–target RNA pairs by parallel analysis of RNA ends

(2008) Marcelo A German et al.   NATURE BIOTECHNOLOGY

The human mitochondrial ribosome recycling factor is essential for cell viability

(2008) Joanna Rorbach et al.   NUCLEIC ACIDS RESEARCH

Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet

(2008) Hrvoje Lusic et al.   NUCLEIC ACIDS RESEARCH

Sequence-specific binding of a chloroplast pentatricopeptide repeat protein to its native group II intron ligand

(2008) R. Williams-Carrier et al.   RNA

Pentatricopeptide repeat proteins: a socket set for organelle gene expression

(2008) C SCHMITZLINNEWEBER et al.   TRENDS IN PLANT SCIENCE