Vascular Pathology as a Potential Therapeutic Target in SCI

Preclinical use of longitudinal MRI for screening the efficacy of s-nitrosoglutathione in treating spinal cord injury

(2011) Peter Cheng-te Chou et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Effect of Vascular Endothelial Growth Factor Treatment in Experimental Traumatic Spinal Cord Injury: In Vivo Longitudinal Assessment

(2011) Laura M. Sundberg et al.   JOURNAL OF NEUROTRAUMA

Reversal of Lysosomal Storage in Brain of Adult MPS-I Mice with Intravenous Trojan Horse-Iduronidase Fusion Protein

(2011) Ruben J. Boado et al.   MOLECULAR PHARMACEUTICS

Targeting Microvasculature for Neuroprotection after SCI

(2011) Janelle M. Fassbender et al.   Neurotherapeutics

Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury

(2011) Haoqian Zhang et al.   Neurotherapeutics

Biomarkers for Severity of Spinal Cord Injury in the Cerebrospinal Fluid of Rats

(2011) Joanna M. Lubieniecka et al.   PLoS One

Blast-induced phenotypic switching in cerebral vasospasm

(2011) P. W. Alford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

Immunolocalization of Aquaporins in Rat Brain

(2011) M. Yang et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Rescuing vasculature with intravenous angiopoietin-1 and  v 3 integrin peptide is protective after spinal cord injury

(2010) S. Han et al.   BRAIN

Neuroprotection in experimental stroke in the rat with an IgG–erythropoietin fusion protein

(2010) Ailing Fu et al.   BRAIN RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Inflammatory and structural biomarkers in acute traumatic spinal cord injury

(2010) Brian K. Kwon et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Spinal Microvascular Expression of PV-1 is Associated with Inflammation, Perivascular Astrocyte Loss, and Diminished EC Glucose Transport Potential in Acute SCI

(2010) Anthony B. Mozer et al.   CURRENT NEUROVASCULAR RESEARCH

Activating Notch signaling post-SCI modulates angiogenesis in penumbral vascular beds but does not improve hindlimb locomotor recovery

(2010) Janelle M. Fassbender et al.   EXPERIMENTAL NEUROLOGY

Laser speckle contrast imaging in biomedical optics

(2010) David A. Boas et al.   JOURNAL OF BIOMEDICAL OPTICS

Neuropathological differences between rats and mice after spinal cord injury

(2010) Kimberly R. Byrnes et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Sustained Expression of Vascular Endothelial Growth Factor and Angiopoietin-1 Improves Blood–Spinal Cord Barrier Integrity and Functional Recovery after Spinal Cord Injury

(2010) Juan J. Herrera et al.   JOURNAL OF NEUROTRAUMA

Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family: Biological Function and Structure

(2010) Theo Klein et al.   JOURNAL OF PROTEOME RESEARCH

Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma

(2010) Ming Zhang et al.   JOURNAL OF SURGICAL ONCOLOGY

Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre-Clinical Models

(2010) DAI FUKUMURA et al.   MICROCIRCULATION

CD47 knockout mice exhibit improved recovery from spinal cord injury

(2010) Scott A. Myers et al.   NEUROBIOLOGY OF DISEASE

Aquaporins in spinal cord injury: the janus face of aquaporin 4

(2010) O. Nesic et al.   NEUROSCIENCE

Matrix Metalloproteinases and Neurotrauma: Evolving Roles in Injury and Reparative Processes

(2010) Haoqian Zhang et al.   NEUROSCIENTIST

Brief Suppression of Abcc8 Prevents Autodestruction of Spinal Cord After Trauma

(2010) J. M. Simard et al.   Science Translational Medicine

Plasminogen activator inhibitor-1 is an aggregate response factor with pleiotropic effects on cell signaling in vascular disease and the tumor microenvironment

(2010) Mark W. Gramling et al.   THROMBOSIS RESEARCH

Neutralizing Endogenous VEGF Following Traumatic Spinal Cord Injury Modulates Microvascular Plasticity but not Tissue Sparing or Functional Recovery

(2009) Richard Benton et al.   CURRENT NEUROVASCULAR RESEARCH

Comparison of Blood-Brain Barrier Transport of Glial-Derived Neurotrophic Factor (GDNF) and an IgG-GDNF Fusion Protein in the Rhesus Monkey

(2009) R. J. Boado et al.   DRUG METABOLISM AND DISPOSITION

The urokinase receptor: Focused cell surface proteolysis, cell adhesion and signaling

(2009) Francesco Blasi et al.   FEBS LETTERS

Axial Diffusivity Is the Primary Correlate of Axonal Injury in the Experimental Autoimmune Encephalomyelitis Spinal Cord: A Quantitative Pixelwise Analysis

(2009) M. D. Budde et al.   JOURNAL OF NEUROSCIENCE

Neurovascular effects of CD47 signaling: Promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitro

(2009) Changhong Xing et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Genetic Ablation of Transcription Repressor Bach1 Reduces Neural Tissue Damage and Improves Locomotor Function after Spinal Cord Injury in Mice

(2009) Haruo Kanno et al.   JOURNAL OF NEUROTRAUMA

Neuronal and Axonal Degeneration in Experimental Spinal Cord Injury: In Vivo Proton Magnetic Resonance Spectroscopy and Histology

(2009) Junchao Qian et al.   JOURNAL OF NEUROTRAUMA

Cerebrospinal Fluid Inflammatory Cytokines and Biomarkers of Injury Severity in Acute Human Spinal Cord Injury

(2009) Brian K. Kwon et al.   JOURNAL OF NEUROTRAUMA

Diffusion Tensor Imaging at 3 Hours after Traumatic Spinal Cord Injury Predicts Long-Term Locomotor Recovery

(2009) Joong H. Kim et al.   JOURNAL OF NEUROTRAUMA

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

(2009) Volodymyr Gerzanich et al.   NATURE MEDICINE

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging

(2009) Benjamin J Vakoc et al.   NATURE MEDICINE

Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury

(2009) Krishna Kumar Veeravalli et al.   NEUROBIOLOGY OF DISEASE

Quantitative analysis by in vivo imaging of the dynamics of vascular and axonal networks in injured mouse spinal cord

(2009) C. Dray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Evaluating regional blood spinal cord barrier dysfunction following spinal cord injury using longitudinal dynamic contrast-enhanced MRI

(2009) Ilkan Tatar et al.   BMC MEDICAL IMAGING

Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice

(2008) S. Saadoun et al.   BRAIN

Glibenclamide Reduces Inflammation, Vasogenic Edema, and Caspase-3 Activation after Subarachnoid Hemorrhage

(2008) J Marc Simard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Transcriptomic Screening of Microvascular Endothelial Cells Implicates Novel Molecular Regulators of Vascular Dysfunction after Spinal Cord Injury

(2008) Richard L Benton et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

ADAM8 is selectively up-regulated in endothelial cells and is associated with angiogenesis after spinal cord injury in adult mice

(2008) Edward T. Mahoney et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Ceruloplasmin Protects Injured Spinal Cord from Iron-Mediated Oxidative Damage

(2008) K. I. Rathore et al.   JOURNAL OF NEUROSCIENCE

Induction of MMP-9 Expression and Endothelial Injury by Oxidative Stress after Spinal Cord Injury

(2008) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Indocyanine green angiography: A new method to quantify collateral flow in mice

(2008) Jan C. Wuestenfeld et al.   JOURNAL OF VASCULAR SURGERY

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke

(2008) Nobuo Nagai et al.   NEUROSCIENCE LETTERS

Brain Perfusion Territory Imaging: Methods and Clinical Applications of Selective Arterial Spin-labeling MR Imaging

(2008) Peter Jan van Laar et al.   RADIOLOGY

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy

(2007) Dimitrios Davalos et al.   JOURNAL OF NEUROSCIENCE METHODS