Reporter Assay for Endo/Lysosomal Escape of Toxin-Based Therapeutics

Real-time analysis of membrane permeabilizing effects of oleanane saponins

(2013) Roger Gilabert-Oriol et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Macromolecular interactions of triterpenoids and targeted toxins: Role of saponins charge

(2013) Mayank Thakur et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Modified Trastuzumab and Cetuximab Mediate Efficient Toxin Delivery While Retaining Antibody-Dependent Cell-Mediated Cytotoxicity in Target Cells

(2013) Roger Gilabert-Oriol et al.   MOLECULAR PHARMACEUTICS

Small structural differences of targeted anti-tumor toxins result in strong variation of protein expression

(2013) Roger Gilabert-Oriol et al.   PROTEIN EXPRESSION AND PURIFICATION

Ribosome-inactivating proteins

(2013) Matthew J Walsh et al.   Virulence

Saponins modulate the intracellular trafficking of protein toxins

(2012) Alexander Weng et al.   JOURNAL OF CONTROLLED RELEASE

The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins

(2012) Alexander Weng et al.   Molecular Oncology

Targeted tumor therapy by epidermal growth factor appended toxin and purified saponin: An evaluation of toxicity and therapeutic potential in syngeneic tumor bearing mice

(2012) Mayank Thakur et al.   Molecular Oncology

Specific functions of lysosomal proteases in endocytic and autophagic pathways

(2011) Sabrina Müller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Mechanism of Diphtheria Toxin Catalytic Domain Delivery to the Eukaryotic Cell Cytosol and the Cellular Factors that Directly Participate in the Process

(2011) John R. Murphy   Toxins

Hsp90 Is Required for Transfer of the Cholera Toxin A1 Subunit from the Endoplasmic Reticulum to the Cytosol

(2010) Michael Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

A Simple Method for Isolation ofGypsophilaSaponins for the Combined Application of Targeted Toxins and Saponins in Tumor Therapy

(2009) Alexander Weng et al.   PLANTA MEDICA

Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition

(2008) Deepa Sikriwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY