Botulinum Neurotoxins and Botulism: A Novel Therapeutic Approach

A Broadly Flavivirus Cross-Neutralizing Monoclonal Antibody that Recognizes a Novel Epitope within the Fusion Loop of E Protein

(2011) Yong-Qiang Deng et al.   PLoS One

Research and development of next generation of antibody-based therapeutics

(2010) Jing Li et al.   ACTA PHARMACOLOGICA SINICA

A Human Single Chain Transbody Specific to Matrix Protein (M1) Interferes with the Replication of Influenza A Virus

(2010) Ornnuthchar Poungpair et al.   BIOCONJUGATE CHEMISTRY

A VHH That Neutralizes the Zinc Metalloproteinase Activity of Botulinum Neurotoxin Type A

(2010) Jeeraphong Thanongsaksrikul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding Region

(2010) Jianbo Dong et al.   JOURNAL OF MOLECULAR BIOLOGY

Llama Single Domain Antibodies Specific for the 7 Botulinum Neurotoxin Serotypes as Heptaplex Immunoreagents

(2010) Jerry O. Conway et al.   PLoS One

Characterization of Botulinum Neurotoxin Type A Neutralizing Monoclonal Antibodies and Influence of Their Half-Lives on Therapeutic Activity

(2010) Christelle Mazuet et al.   PLoS One

Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating

(2010) J. Lou et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Peptide-mediated cancer targeting of nanoconjugates

(2010) Sumita Raha et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Antibody Protection against Botulinum Neurotoxin Intoxication in Mice

(2009) L. W. Cheng et al.   INFECTION AND IMMUNITY

Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxin

(2009) Kasem Kulkeaw et al.   Journal of Proteomics

Human single chain monoclonal antibody that recognizes matrix protein of heterologous influenza A virus subtypes

(2009) Ornnuthchar Poungpair et al.   JOURNAL OF VIROLOGICAL METHODS

Development trends for therapeutic antibody fragments

(2009) Aaron L Nelson et al.   NATURE BIOTECHNOLOGY

Receptor-mediated endocytosis in renal proximal tubule

(2009) Erik Ilsø Christensen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Evidence that Plasmid-Borne Botulinum Neurotoxin Type B Genes Are Widespread among Clostridium botulinum Serotype B Strains

(2009) Giovanna Franciosa et al.   PLoS One

Humanized-monoclonal antibody against heterologous Leptospira infection

(2009) S. Maneewatch et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Immune recognition of BoNTs A and B: How anti-toxin antibodies that bind to the heavy chain obstruct toxin action

(2009) M. Zouhair Atassi   TOXICON

Receptor and substrate interactions of clostridial neurotoxins

(2009) Axel T. Brunger et al.   TOXICON

Cell-penetrating peptides: from molecular mechanisms to therapeutics

(2008) May C. Morris et al.   BIOLOGY OF THE CELL

Highly specific interactions between botulinum neurotoxins and synaptic vesicle proteins

(2008) A. T. Brunger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Isolation of human monoclonal antibodies by mammalian cell display

(2008) R. R. Beerli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel function of botulinum toxin-associated proteins: HA proteins disrupt intestinal epithelial barrier to increase toxin absorption

(2008) Y. Fujinaga et al.   TOXICON