Induced Pluripotent Stem Cells Reveal Functional Differences Between Drugs Currently Investigated in Patients With Hutchinson-Gilford Progeria Syndrome

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome

(2012) John J. Graziotto et al.   Autophagy

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

(2012) L. B. Gordon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

(2012) Xavier Nissan et al.   Cell Reports

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

(2011) Guang-Hui Liu et al.   Cell Stem Cell

Les cellules souches pluripotentes humaines

(2011) Yves Maury et al.   M S-MEDECINE SCIENCES

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

(2011) K. Cao et al.   Science Translational Medicine

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined mRNA and microRNA profiling reveals that miR-148a and miR-20b control human mesenchymal stem cell phenotype via EPAS1

(2010) Karine Giraud-Triboult et al.   PHYSIOLOGICAL GENOMICS

Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging

(2009) Sofia Rodriguez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients

(2009) Gabriela Viteri et al.   MECHANISMS OF AGEING AND DEVELOPMENT

HGPS and related premature aging disorders: From genomic identification to the first therapeutic approaches

(2008) Sandrine Pereira et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

(2008) B. C. Capell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA