Intercellular protein–protein interactions at synapses

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease

(2017) Ana María Simón et al.   JOURNAL OF ALZHEIMERS DISEASE

Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking

(2013) Jason Aoto et al.   CELL

F3/Contactin promotes hippocampal neurogenesis, synaptic plasticity, and memory in adult mice

(2013) Daniela Puzzo et al.   HIPPOCAMPUS

Neural Cell Adhesion Molecule-Mediated Fyn Activation Promotes GABAergic Synapse Maturation in Postnatal Mouse Cortex

(2013) B. Chattopadhyaya et al.   JOURNAL OF NEUROSCIENCE

Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation

(2013) O. Gokce et al.   JOURNAL OF NEUROSCIENCE

NGL-2 Regulates Pathway-Specific Neurite Growth and Lamination, Synapse Formation, and Signal Transmission in the Retina

(2013) F. Soto et al.   JOURNAL OF NEUROSCIENCE

Axonal Translation of  -Catenin Regulates Synaptic Vesicle Dynamics

(2013) A. M. Taylor et al.   JOURNAL OF NEUROSCIENCE

A role for the neurexin–neuroligin complex in Alzheimer's disease

(2013) Ikhlas A. Sindi et al.   NEUROBIOLOGY OF AGING

Leucine-Rich Repeat Transmembrane Proteins Are Essential for Maintenance of Long-Term Potentiation

(2013) Gilberto J. Soler-Llavina et al.   NEURON

An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells

(2013) Tabrez J. Siddiqui et al.   NEURON

A Key Role for Nectin-1 in the Ventral Hippocampus in Contextual Fear Memory

(2013) Martina Fantin et al.   PLoS One

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases

(2013) Y. S. Yim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNAP-25 regulates spine formation through postsynaptic binding to p140Cap

(2013) Romana Tomasoni et al.   Nature Communications

Neurexins

(2013) Carsten Reissner et al.   GENOME BIOLOGY

Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites

(2013) O. Mercati et al.   Biology Open

LRRTM1-deficient mice show a rare phenotype of avoiding small enclosures—A tentative mouse model for claustrophobia-like behaviour

(2012) V. Voikar et al.   BEHAVIOURAL BRAIN RESEARCH

C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β

(2012) Aksana Andreyeva et al.   BRAIN

Involvement of the γ-Secretase-Mediated EphA4 Signaling Pathway in Synaptic Pathogenesis of Alzheimer's Disease

(2012) Chiyuki Matsui et al.   BRAIN PATHOLOGY

β3 integrin is dispensable for conditioned fear and Hebbian forms of plasticity in the hippocampus

(2012) A. B. McGeachie et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Disruption of Contactin 4 in two subjects with autism in Chinese population

(2012) Hui Guo et al.   GENE

EphA Signaling Promotes Actin-based Dendritic Spine Remodeling through Slingshot Phosphatase

(2012) Lei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions between ICAM-5 and β1 integrins regulate neuronal synapse formation

(2012) Lin Ning et al.   JOURNAL OF CELL SCIENCE

The role of nectins in different types of cell-cell adhesion

(2012) Y. Rikitake et al.   JOURNAL OF CELL SCIENCE

Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity

(2012) Katherine E. Horn et al.   JOURNAL OF NEUROCHEMISTRY

Ephrin regulation of synapse formation, function and plasticity

(2012) Martin Hruska et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction

(2012) Hideto Takahashi et al.   NATURE NEUROSCIENCE

The kinase activity of EphA4 mediates homeostatic scaling-down of synaptic strength via activation of Cdk5

(2012) Yi-Rong Peng et al.   NEUROPHARMACOLOGY

The Synaptic Adhesion Molecule SynCAM 1 Contributes to Cocaine Effects on Synapse Structure and Psychostimulant Behavior

(2012) Joanna I Giza et al.   NEUROPSYCHOPHARMACOLOGY

Cadherins in Brain Morphogenesis and Wiring

(2012) Shinji Hirano et al.   PHYSIOLOGICAL REVIEWS

 3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons

(2012) K. Pozo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contactin 4 as an autism susceptibility locus

(2011) Catherine E. Cottrell et al.   Autism Research

Eph receptors at synapses: Implications in neurodegenerative diseases

(2011) Yu Chen et al.   CELLULAR SIGNALLING

Cadherin-catenin adhesion complexes at the synapse

(2011) G Stefano Brigidi et al.   CURRENT OPINION IN NEUROBIOLOGY

Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation

(2011) Adam I Fogel et al.   EMBO JOURNAL

Consensus Document on European Brain Research

(2011) Monica Di Luca et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dileucine and PDZ-binding Motifs Mediate Synaptic Adhesion-like Molecule 1 (SALM1) Trafficking in Hippocampal Neurons

(2011) Gail K. Seabold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons

(2011) Jaewon Ko et al.   JOURNAL OF CELL BIOLOGY

Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic β1-integrin

(2011) Steven Mortillo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Characterization of nectin processing mediated by presenilin-dependent gamma-secretase

(2011) Jinsook Kim et al.   JOURNAL OF NEUROCHEMISTRY

N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production

(2011) Megumi Asada-Utsugi et al.   JOURNAL OF NEUROCHEMISTRY

EphA4 expression promotes network activity and spine maturation in cortical neuronal cultures

(2011) Meredith A Clifford et al.   Neural Development

Social responsiveness scale-aided analysis of the clinical impact of copy number variations in autism

(2011) Emma van Daalen et al.   NEUROGENETICS

Postsynaptic TrkC and Presynaptic PTPσ Function as a Bidirectional Excitatory Synaptic Organizing Complex

(2011) Hideto Takahashi et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

The dynamic role of beta-catenin in synaptic plasticity

(2011) Kimberly A. Maguschak et al.   NEUROPHARMACOLOGY

Presenilin/γ-Secretase Regulates Neurexin Processing at Synapses

(2011) Carlos A. Saura et al.   PLoS One

The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo

(2011) G. J. Soler-Llavina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ephrin reverse signaling in axon guidance and synaptogenesis

(2011) Nan-Jie Xu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ectodomain structures of Eph receptors

(2011) Juha P. Himanen   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Non-SH2/PDZ reverse signaling by ephrins

(2011) Ira O. Daar   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Structure of Neurexin 1α Reveals Features Promoting a Role as Synaptic Organizer

(2011) Fang Chen et al.   STRUCTURE

Munc18 and Munc13 regulate early neurite outgrowth

(2010) Jurjen H.P. Broeke et al.   BIOLOGY OF THE CELL

SnapShot: Neuroligin-Neurexin Complexes

(2010) Stéphane Baudouin et al.   CELL

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

Perisomatic GABAergic Innervation in Prefrontal Cortex Is Regulated by Ankyrin Interaction with the L1 Cell Adhesion Molecule

(2010) H. Guan et al.   CEREBRAL CORTEX

Organization of central synapses by adhesion molecules

(2010) Alexandra Tallafuss et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genome-scan for IQ discrepancy in autism: evidence for loci on chromosomes 10 and 16

(2010) Nicola H. Chapman et al.   HUMAN GENETICS

N-cadherin and Neuroligins Cooperate to Regulate Synapse Formation in Hippocampal Cultures

(2010) Mytyl Aiga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

(2010) Nathalie Bot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans-synaptic Adhesions between Netrin-G Ligand-3 (NGL-3) and Receptor Tyrosine Phosphatases LAR, Protein-tyrosine Phosphatase δ (PTPδ), and PTPσ via Specific Domains Regulate Excitatory Synapse Formation

(2010) Seok-Kyu Kwon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-cadherin mediates plasticity-induced long-term spine stabilization

(2010) Pablo Mendez et al.   JOURNAL OF CELL BIOLOGY

Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability

(2010) A. T. Pagnamenta et al.   JOURNAL OF MEDICAL GENETICS

β-Catenin Promoter ChIP-Chip Reveals Potential Schizophrenia and Bipolar Disorder Gene Network

(2010) Erika Pedrosa et al.   JOURNAL OF NEUROGENETICS

Selected SALM (Synaptic Adhesion-Like Molecule) Family Proteins Regulate Synapse Formation

(2010) W. Mah et al.   JOURNAL OF NEUROSCIENCE

Persistence of Coordinated Long-Term Potentiation and Dendritic Spine Enlargement at Mature Hippocampal CA1 Synapses Requires N-Cadherin

(2010) O. Bozdagi et al.   JOURNAL OF NEUROSCIENCE

Ephrin-B3 regulates glutamate receptor signaling at hippocampal synapses

(2010) Marcia D. Antion et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

(2010) Amy K Y Fu et al.   NATURE NEUROSCIENCE

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits

(2010) Megan E. Williams et al.   NEURON

SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

(2010) Elissa M. Robbins et al.   NEURON

Synaptic formation in subsets of glutamatergic terminals in the mouse hippocampal formation is affected by a deficiency in the neural cell recognition molecule NB-3

(2010) Kunie Sakurai et al.   NEUROSCIENCE LETTERS

The 14-3-3ζ Protein Binds to the Cell Adhesion Molecule L1, Promotes L1 Phosphorylation by CKII and Influences L1-Dependent Neurite Outgrowth

(2010) Elisa M. Ramser et al.   PLoS One

Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation

(2010) A. Stan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many Paths to Synaptic Specificity

(2009) Joshua R. Sanes et al.   Annual Review of Cell and Developmental Biology

Involvement of afadin in the formation and remodeling of synapses in the hippocampus

(2009) Takashi Majima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The intracellular interactions of the L1 family of cell adhesion molecules

(2009) Lissa R. Herron et al.   BIOCHEMICAL JOURNAL

IgLON cell adhesion molecules regulate synaptogenesis in hippocampal neurons

(2009) Takashi Hashimoto et al.   CELL BIOCHEMISTRY AND FUNCTION

Contribution of the neural cell recognition molecule NB-3 to synapse formation between parallel fibers and Purkinje cells in mouse

(2009) Kunie Sakurai et al.   Developmental Neurobiology

Identification of ANKRD11 and ZNF778 as candidate genes for autism and variable cognitive impairment in the novel 16q24.3 microdeletion syndrome

(2009) Marjolein H Willemsen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Peptide EphB2/CTF2 Generated by the γ-Secretase Processing of EphB2 Receptor Promotes Tyrosine Phosphorylation and Cell Surface Localization ofN-Methyl-d-aspartate Receptors

(2009) Jindong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

(2009) Eiji Inoue et al.   JOURNAL OF CELL BIOLOGY

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

A Neuroligin-4 Missense Mutation Associated with Autism Impairs Neuroligin-4 Folding and Endoplasmic Reticulum Export

(2009) C. Zhang et al.   JOURNAL OF NEUROSCIENCE

SynCAM1 recruits NMDA receptors via Protein 4.1B

(2009) Jennifer L. Hoy et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Replication of GWAS of bipolar disorder: association of SNPs near CDH7 with bipolar disorder and visual processing

(2009) P Soronen et al.   MOLECULAR PSYCHIATRY

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

(2009) Esperanza Fernández et al.   Molecular Systems Biology

Common genetic variants on 5p14.1 associate with autism spectrum disorders

(2009) Kai Wang et al.   NATURE

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

(2009) Minerva M Carrasquillo et al.   NATURE GENETICS

Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses

(2009) Jooyeon Woo et al.   NATURE NEUROSCIENCE

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

(2009) Alessandro Filosa et al.   NATURE NEUROSCIENCE

Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis

(2009) Stephanie L Barrow et al.   Neural Development

An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers

(2009) Michael W. Linhoff et al.   NEURON

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

The Post-Synaptic Density of Human Postmortem Brain Tissues: An Experimental Study Paradigm for Neuropsychiatric Illnesses

(2009) Chang-Gyu Hahn et al.   PLoS One

Cell Adhesion, the Backbone of the Synapse: "Vertebrate" and "Invertebrate" Perspectives

(2009) N. Giagtzoglou et al.   Cold Spring Harbor Perspectives in Biology

A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-α

(2009) Bryony A Dickinson et al.   Molecular Brain

Recurrent CNVs Disrupt Three Candidate Genes in Schizophrenia Patients

(2008) Terry Vrijenhoek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons

(2008) Takashi Hashimoto et al.   BRAIN RESEARCH

CASK Functions as a Mg2+-Independent Neurexin Kinase

(2008) Konark Mukherjee et al.   CELL

The SALM Family of Adhesion-like Molecules Forms Heteromeric and Homomeric Complexes

(2008) Gail K. Seabold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons

(2008) Seung T. Lim et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions

(2008) Lisa A. Thomas et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth

(2008) Philip Y. Wang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Whole-genome association study of bipolar disorder

(2008) P Sklar et al.   MOLECULAR PSYCHIATRY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE

EphB Receptors Couple Dendritic Filopodia Motility to Synapse Formation

(2008) Matthew S. Kayser et al.   NEURON

Activity-Dependent Regulation of Synaptic AMPA Receptor Composition and Abundance by β3 Integrins

(2008) Lorenzo A. Cingolani et al.   NEURON

Alternative splicing of neurexins: A role for neuronal polypyrimidine tract binding protein

(2008) Mika Resnick et al.   NEUROSCIENCE LETTERS

Neurexin 1α structural variants associated with autism

(2008) Jin Yan et al.   NEUROSCIENCE LETTERS

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons

(2008) K. Deininger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts

(2008) M. Heine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Autism Loci and Genes by Tracing Recent Shared Ancestry

(2008) E. M. Morrow et al.   SCIENCE

Bergmann Glia and the Recognition Molecule CHL1 Organize GABAergic Axons and Direct Innervation of Purkinje Cell Dendrites

(2008) Fabrice Ango et al.   PLOS BIOLOGY