Article
Multidisciplinary Sciences
Wajd Abbas Hassan Hansen, Vivi Schlunssen, Erik Jors, Daniel Sekabojja, John C. Ssempebwa, Ruth Mubeezi, Philipp Staudacher, Samuel Fuhrimann, Martin Rune Hassan Hansen
Summary: The study evaluated the accuracy and precision of the copd-6 mini-spirometer for FEV1 in a rural Ugandan population, finding that it underestimated FEV1 at low flows and overestimated FEV1 at high flows, with a slight overall overestimation of 0.04 liters. The conclusion suggested that the copd-6 could be considered as an affordable tool for research on lung function impairment in resource-constrained settings, but further validation in a population with obstructive lung disease is needed.
Article
Medicine, General & Internal
Ching-Hsiung Lin, Shih-Lung Cheng, Hao-Chien Wang, Wu-Huei Hsu, Kang-Yun Lee, Diahn-Warng Perng, Hen-I. Lin, Ming-Shian Lin, Jong-Rung Tsai, Chin-Chou Wang, Sheng-Hao Lin, Cheng-Yi Wang, Chiung-Zuei Chen, Tsung-Ming Yang, Ching-Lung Liu, Tsai-Yu Wang, Meng-Chih Lin
Summary: The use of an app-based spirometer, Spirobank Smart, facilitates early detection of COPD in outpatient clinics, helping undiagnosed and untreated patients. Early diagnosis and appropriate therapy based on GOLD guidelines can significantly impact respiratory symptoms and quality of life.
Article
Critical Care Medicine
Yunus Colak, Shoaib Afzal, Borge G. Nordestgaard, Peter Lange, Jorgen Vestbo
Summary: This study suggests that it is possible to identify individuals who may develop chronic obstructive pulmonary disease (COPD) at an early age. Smoking exposure is an important factor associated with the development of COPD, with smokers having a higher risk compared to non-smokers.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Allergy
Bulent Enis Sekerel, Hilal Unsal, Umit Murat Sahiner, Ozge Uysal Soyer, Ebru Damadoglu, Gul Karakaya, Ali Fuat Kalyoncu
Summary: This study examined the accuracy and repeatability of lung function measurements using the Spirohome Clinic hand-held ultrasonic spirometer compared to the EasyOne Air reference device. The results showed strong correlation between the two spirometers in measuring key pulmonary function parameters and both met the accuracy requirements stated in relevant guidelines and standards for spirometry. These findings support the clinical use of the Spirohome Clinic for high-quality lung function testing.
JOURNAL OF ASTHMA AND ALLERGY
(2022)
Article
Economics
Kate M. Johnson, Mohsen Sadatsafavi, Amin Adibi, Larry Lynd, Mark Harrison, Hamid Tavakoli, Don D. Sin, Stirling Bryan
Summary: This study evaluated the cost effectiveness of 16 case detection strategies for COPD and found that primary care-based case detection programs are likely to be cost effective under certain conditions, if best-practice recommendations for treatment are adhered to, alleviating symptoms in newly diagnosed patients.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2021)
Article
Public, Environmental & Occupational Health
Xin Yin, Zixuan Zheng, Yue Dong, Junqing Li, Shuang Yang, Qian Xu, Shanshan Hou, Yi Zang, Heyuan Ding, Juan Xie, Zhijun Jie, Qingwu Jiang, Jindong Shi, Na Wang
Summary: This study investigated whether spirometry screening is necessary for the general population in Minhang, Shanghai, China, especially those without characteristic symptoms of chronic obstructive pulmonary disease (COPD). The results showed that half of the newly diagnosed mild to moderate COPD patients were asymptomatic. Multivariate analysis revealed that age, sex, and respiratory symptoms were associated with the severity of airflow limitation in COPD patients. Therefore, a targeted case finding strategy is currently preferred over general screening.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Engineering, Electrical & Electronic
Ana Catarina Nepomuceno, Nelia Alberto, Paulo Andre, Paulo Fernando da Costa Antunes, Maria de Fatima Domingues
Summary: The evaluation of lung functionality through spirometry provides information on various respiratory parameters, such as forced vital capacity, first second forced expiratory volume, peak expiratory flow, and FEV1/FVC ratio. This study proposed a spirometer based on fiber Bragg gratings integrated in a 3D printed structure, showing promising results compared to a commercial handheld spirometer.
IEEE SENSORS JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Piotr Jankowski, Katarzyna Gorska, Katarzyna Mycroft, Piotr Korczynski, Mateusz Solinski, Lukasz Koltowski, Rafal Krenke
Summary: This study investigated the feasibility of using the AioCare(R) mobile spirometer in primary care, finding that operator age and repetition of the examination were associated with technically correct examinations. Airway obstruction was found in a significant portion of correctly performed spirometry examinations.
RESPIRATORY MEDICINE
(2021)
Article
Primary Health Care
Shuli Qu, Xuedan You, Tianyi Liu, Lijiao Wang, Zheng Yin, Yanjun Liu, Chong Ye, Ting Yang, Mao Huang, Hongchao Li, Liwen Fang, Jinping Zheng
Summary: A decision-analytic model was used to compare the cost-effectiveness of portable spirometer and questionnaire screening for COPD among chronic bronchitis patients in China. The results indicated that portable spirometer screening was cost-saving, with sensitivity analyses confirming the robustness of the findings. In summary, portable spirometer screening may be the optimal option for COPD screening in this population.
NPJ PRIMARY CARE RESPIRATORY MEDICINE
(2021)
Article
Critical Care Medicine
Catherine John, Anna L. Guyatt, Nick Shrine, Richard Packer, Thorunn A. Olafsdottir, Jiangyuan Liu, Lystra P. Hayden, Su H. Chu, Jukka T. Koskela, Jian'an Luan, Xingnan Li, Natalie Terzikhan, Hanfei Xu, Traci M. Bartz, Hans Petersen, Shuguang Leng, Steven A. Belinsky, Aivaras Cepelis, Ana I. Hernandez Cordero, Ma'en Obeidat, Gudmar Thorleifsson, Deborah A. Meyers, Eugene R. Bleecker, Lori C. Sakoda, Carlos Iribarren, Yohannes Tesfaigzi, Sina A. Gharib, Josee Dupuis, Guy Brusselle, Lies Lahousse, Victor E. Ortega, Ingileif Jonsdottir, Don D. Sin, Yohan Bosse, Maarten van den Berge, David Nickle, Jennifer K. Quint, Ian Sayers, Ian P. Hall, Claudia Langenberg, Samuli Ripatti, Tarja Laitinen, Ann C. Wu, Jessica Lasky-Su, Per Bakke, Amund Gulsvik, Craig P. Hersh, Caroline Hayward, Arnulf Langhammer, Ben Brumpton, Kari Stefansson, Michael H. Cho, Louise Wain, Martin D. Tobin
Summary: This study identified genetic variants associated with asthma-COPD overlap and discovered shared genetic influences that may predispose individuals to type 2 inflammation and serious long-term consequences of asthma.
Review
Infectious Diseases
Kira Elsbernd, Karl M. F. Emmert-Fees, Amanda Erbe, Veronica Ottobrino, Arne Kroidl, Till Barnighausen, Benjamin P. Geisler, Stefan Kohler
Summary: This scoping review summarizes the available evidence on the cost and cost-effectiveness of HIV early infant diagnosis (EID). The results suggest that most interventions designed to improve EID are cost-effective or cost-saving. However, comparing costs across studies is challenging due to heterogeneity in reporting. More studies are needed to capture the costs and benefits of delivering EID services in real-world settings.
INFECTIOUS DISEASES OF POVERTY
(2022)
Review
Cardiac & Cardiovascular Systems
D. Pellegrino, S. Casas-Recasens, R. Faner, P. Palange, A. Agusti
Summary: The term GETomics refers to the concept that human health and disease are the result of dynamic gene-environment interactions occurring throughout a person's lifetime. This approach has led to a dramatic shift in our understanding of chronic obstructive pulmonary disease (COPD), as it is not solely caused by smoking and affects both genders and different age groups. By applying a GETomics approach, new perspectives on the relationship between COPD, exercise limitation, and aging can be gained.
RESPIRATORY MEDICINE
(2023)
Article
Clinical Neurology
Jose Contador, Ana Magdalena Vargas-Martinez, Raquel Sanchez-Valle, Marta Trapero-Bertran, Albert Llado
Summary: This study compares the cost-effectiveness of amyloid-positron emission tomography (PET) and Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers for the diagnosis of AD in patients with early-onset cognitive impairment. The findings suggest that Amyloid-PET can provide more accurate diagnoses of AD compared to AD CSF biomarkers, but it is not cost-effective unless the funder is willing to pay a certain amount.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Gatien De Broucker, Phillip P. Salvatore, Simon Mutembo, Nkumbula Moyo, Jane N. Mutanga, Philip E. Thuma, William J. Moss, Catherine G. Sutcliffe
Summary: The study found that point-of-care (PoC) testing can improve the timeliness and coverage of diagnosis and ART treatment for HIV-infected infants with favorable cost-effectiveness.
Article
Critical Care Medicine
Nathan Yee, Daniela Markovic, Russell G. Buhr, Spyridon Fortis, Mehrdad Arjomandi, David Couper, Wayne H. Anderson, Robert Paine, Prescott G. Woodruff, Meilan K. Han, Fernando J. Martinez, R. Graham Barr, James M. Wells, Victor E. Ortega, Eric A. Hoffman, Victor Kim, M. Bradley Drummond, Russell P. Bowler, Jeffrey L. Curtis, Christopher B. Cooper, Donald P. Tashkin, Igor Z. Barjaktarevic
Summary: The study found that FEV3/FEV6 below the lower limit of normal is associated with the development and worsening of various respiratory-related diseases, including COPD. This spirometric index can be used to identify early airflow abnormalities and has important implications for patient evaluation and prediction.